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Hajime Takizawa

Hajime Takizawa

D-Index & Metrics

Immunology

D-Index
45
Citations
7945
World Ranking
4700
National Ranking
179

Overview

Hajime Takizawa is affiliated with the University of Tokyo in Japan and focuses their research primarily within the field of Medicine. Their work encompasses several subfields including Hematology, Immunology, Molecular Biology, Oncology, and Genetics.

The scientist has contributed to research covering a range of main topics, particularly:

  • Hematopoietic Stem Cell Transplantation
  • Acute Myeloid Leukemia Research
  • Immune cells in cancer
  • Immune responses and vaccinations
  • Immune Response and Inflammation
  • Immune Cell Function and Interaction
  • Neuroinflammation and Neurodegeneration Mechanisms

Takizawa has collaborated frequently with other researchers including Maiko Sezaki, Tatsuya Morishima, Terumasa Umemoto, Toshio Suda, and T. Matsubara.

Their publications have appeared predominantly in the following venues:

  • Experimental Hematology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Zenodo (CERN European Organization for Nuclear Research)
  • Blood

Significant recent papers authored or co-authored by Takizawa include:

  • IL-1 mediates microbiome-induced inflammaging of hematopoietic stem cells in mice, 2021, Blood
  • Remote control of neural function by X-ray-induced scintillation, 2021, Nature Communications
  • Unique molecular and functional features of extramedullary hematopoietic stem and progenitor cell reservoirs in humans, 2022, Blood
  • Fit-For-All iPSC-Derived Cell Therapies and Their Evaluation in Humanized Mice With NK Cell Immunity, 2021, Frontiers in Immunology
  • Inflammation Regulates Haematopoietic Stem Cells and Their Niche, 2022, International Journal of Molecular Sciences

Best Publications

  • Intervention of thymus and activation-regulated chemokine attenuates the development of allergic airway inflammation and hyperresponsiveness in mice

    Shin Kawasaki;Hajime Takizawa;Hiroyuki Yoneyama;Takashi Nakayama

  • Erythromycin modulates IL-8 expression in normal and inflamed human bronchial epithelial cells.

    Hajime Takizawa;Masashi Desaki;Takayuki Ohtoshi;Shin Kawasaki

  • Clinical implications of the immunomodulatory effects of macrolides.

    Jun Tamaoki;Junichi Kadota;Hajime Takizawa

  • Diesel exhaust particles induce NF-kappa B activation in human bronchial epithelial cells in vitro: importance in cytokine transcription.

    Hajime Takizawa;Takayuki Ohtoshi;Shin Kawasaki;Tadashi Kohyama

  • Diesel exhaust particles stimulate human airway epithelial cells to produce cytokines relevant to airway inflammation in vitro

    Takayuki Ohtoshi;Hajime Takizawa;Hitoshi Okazaki;Shin Kawasaki

  • Erythromycin suppresses nuclear factor-kappaB and activator protein-1 activation in human bronchial epithelial cells.

    Masashi Desaki;Hajime Takizawa;Takayuki Ohtoshi;Tsuyoshi Kasama

  • Potential action of IL-4 and IL-13 as fibrogenic factors on lung fibroblasts in vitro.

    Akira Saito;Hitoshi Okazaki;Isamu Sugawara;Kazuhiko Yamamoto

  • Diesel Exhaust Particles Activate p38 MAP Kinase to Produce Interleukin 8 and RANTES by Human Bronchial Epithelial Cells and N-Acetylcysteine Attenuates p38 MAP Kinase Activation

    Shu Hashimoto;Yasuhiro Gon;Ikuko Takeshita;Ken Matsumoto

  • Virus-induced exacerbations in asthma and COPD

    Unknown

  • Diesel Exhaust (DE)-Induced Cytokine Expression in Human Bronchial Epithelial Cells A Study with a New Cell Exposure System to Freshly Generated DE In Vitro

    Shinji Abe;Hajime Takizawa;Isamu Sugawara;Shoji Kudoh

  • Growth inhibition of human lung cancer cell lines by interleukin 6 in vitro: a possible role in tumor growth via an autocrine mechanism.

    Hajime Takizawa;Takayuki Ohtoshi;Ken Ohta;Naomi Yamashita

  • Benzene-extracted components are important for the major activity of diesel exhaust particles: effect on interleukin-8 gene expression in human bronchial epithelial cells.

    Shin Kawasaki;Hajime Takizawa;Kazutaka Takami;Masashi Desaki

  • Molecular Mechanisms of Anti-Inflammatory Action of Erythromycin in Human Bronchial Epithelial Cells: Possible Role in the Signaling Pathway That Regulates Nuclear Factor-κB Activation

    Masashi Desaki;Hitoshi Okazaki;Toshiaki Sunazuka;Satoshi Omura

  • Roxithromycin Inhibits Cytokine Production by and Neutrophil Attachment to Human Bronchial Epithelial Cells In Vitro

    Shin Kawasaki;Hajime Takizawa;Takayuki Ohtoshi;Naonobu Takeuchi

  • A novel snake venom vascular endothelial growth factor (VEGF) predominantly induces vascular permeability through preferential signaling via VEGF receptor-1.

    Hiroyuki Takahashi;Shosaku Hattori;Akihiro Iwamatsu;Hajime Takizawa

  • Endotoxin and pro-inflammatory cytokines stimulate endothelin-1 expression and release by airway epithelial cells.

    J. Nakano;H. Takizawa;T. Ohtoshi;S. Shoji

  • Novel aspects on the pathogenesis of Mycoplasma pneumoniae pneumonia and therapeutic implications.

    Takeshi Saraya;Daisuke Kurai;Kazuhide Nakagaki;Yoshiko Sasaki

  • Increased IL‐6 and IL‐8 in bronchoalveolar lavage fluids (BALF) from patients with sarcoidosis: correlation with the clinical parameters

    H. Takizawa;M. Satoh;H. Okazaki;G. Matsuzaki

  • Increased expression of inflammatory mediators in small-airway epithelium from tobacco smokers.

    Hajime Takizawa;Mitsuru Tanaka;Kazutaka Takami;Takayuki Ohtoshi

  • Anti‐gal‐C antibody in autoimmune neuropathies subsequent to mycoplasma infection

    Susumu Kusunoki;Atsuro Chiba;Seiji Hitoshi;Hajime Takizawa

  • Fourteen-member macrolides inhibit interleukin-8 release by human eosinophils from atopic donors.

    Tadashi Kohyama;Hajime Takizawa;Shin Kawasaki;Norihisa Akiyama

  • Macrolide effects on the prevention of COPD exacerbations

    Mutsuo Yamaya;Arata Azuma;Hajime Takizawa;Jun-ichi Kadota

  • Diesel exhaust particles and their effect on induced cytokine expression in human bronchial epithelial cells.

    Hajime Takizawa

  • Diesel exhaust particles activate human bronchial epithelial cells to express inflammatory mediators in the airways: A review

    Hajime Takizawa;Takayuki Ohtoshi;Shin Kawasaki;Shinji Abe

Frequent Co-Authors

Ken Ohta
Ken Ohta Teikyo University
Shoji Kudoh
Shoji Kudoh Nippon Medical School
Isamu Sugawara
Isamu Sugawara Saitama Medical University
Stephen I. Rennard
Stephen I. Rennard University of Nebraska Medical Center
Kouji Matsushima
Kouji Matsushima Tokyo University of Science
Takashi Ueda
Takashi Ueda National Institute for Basic Biology
Satoshi Omura
Satoshi Omura Kitasato University
Kazuo Kobayashi
Kazuo Kobayashi National Institute of Infectious Diseases
Debra J. Romberger
Debra J. Romberger University of Nebraska Medical Center

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