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D-Index & Metrics

Medicine

D-Index
83
Citations
17722
World Ranking
15825
National Ranking
7964

Overview

Anantha Shekhar is affiliated with Indiana University in the United States and works primarily within the fields of Medicine and Neuroscience. Their publication record highlights a substantial focus on molecular and physiological aspects of brain function and disorders.

Their research spans several subfields including Molecular Biology, Physiology, Cellular and Molecular Neuroscience, Biological Psychiatry, and Cognitive Neuroscience. This interdisciplinary approach supports investigations into complex neurobiological mechanisms and pharmacological interventions.

Main topics featured across their publications include:

  • Tryptophan and brain disorders
  • Sleep and Wakefulness Research
  • Circadian rhythm and melatonin
  • Neuroscience and Neuropharmacology Research
  • Treatment of Major Depression
  • Nitric Oxide and Endothelin Effects
  • Sleep and related disorders

They have contributed to several peer-reviewed journals with frequent publications in:

  • Molecular Psychiatry
  • Journal of Clinical and Translational Science
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Pharmacology and Experimental Therapeutics
  • Translational Psychiatry

Notable recent papers authored or co-authored by Anantha Shekhar include:

  • Precision medicine for mood disorders: objective assessment, risk prediction, pharmacogenomics, and repurposed drugs (2021, Molecular Psychiatry)
  • Translational evaluation of novel selective orexin-1 receptor antagonist JNJ-61393215 in an experimental model for panic in rodents and humans (2020, Translational Psychiatry)
  • Disrupting nNOS-PSD95 Interaction Improves Neurological and Cognitive Recoveries after Traumatic Brain Injury (2020, Cerebral Cortex)
  • Ubiquitination and degradation of SUMO1 by small-molecule degraders extends survival of mice with patient-derived tumors (2021, Science Translational Medicine)
  • Specific Lowering of Asymmetric Dimethylarginine by Pharmacological Dimethylarginine Dimethylaminohydrolase Improves Endothelial Function, Reduces Blood Pressure and Ischemia-Reperfusion Injury (2020, Journal of Pharmacology and Experimental Therapeutics)

They have collaborated frequently with several co-authors, notably including H Le-Niculescu, Sunil M. Kurian, Andrei I. Molosh, Alexander B. Niculescu, and William A. Truitt, each having multiple joint publications.

Best Publications

  • Selective Muscarinic Receptor Agonist Xanomeline as a Novel Treatment Approach for Schizophrenia

    Anantha Shekhar;William Z. Potter;Jeffrey Lightfoot;John Lienemann

  • Convergent functional genomics of schizophrenia: from comprehensive understanding to genetic risk prediction.

    M. Ayalew;H. Le-Niculescu;D. F. Levey;N. Jain

  • Modulation of anxiety circuits by serotonergic systems.

    Christopher A. Lowry;Philip L. Johnson;Anders Hay-Schmidt;Jens Mikkelsen

  • Suppression of inflammatory and neuropathic pain by uncoupling CRMP-2 from the presynaptic Ca2+ channel complex

    Joel M. Brittain;Djane B. Duarte;Sarah M. Wilson;Weiguo Zhu

  • Differential effects of exposure to low-light or high-light open-field on anxiety-related behaviors: Relationship to c-Fos expression in serotonergic and non-serotonergic neurons in the dorsal raphe nucleus

    J. Adriaan Bouwknecht;Francesca Spiga;Daniel R. Staub;Matthew W. Hale

  • Discovery and validation of blood biomarkers for suicidality

    H Le-Niculescu;H Le-Niculescu;D F Levey;M Ayalew;L Palmer

  • Stress-related serotonergic systems: implications for symptomatology of anxiety and affective disorders.

    Matthew W. Hale;Anantha Shekhar;Christopher A. Lowry

  • GABA receptors in the region of the dorsomedial hypothalamus of rats regulate anxiety in the elevated plus-maze test. II. Physiological measures

    Anantha Shekhar;L. S. Sims;R. R. Bowsher

  • Brain imaging studies in mood and anxiety disorders: special emphasis on the amygdala.

    Amit Anand;Anantha Shekhar

  • Excitatory amino acid receptors in the basolateral amygdala regulate anxiety responses in the social interaction test

    T. J. Sajdyk;Anantha Shekhar

  • Multicenter, randomized, double-blind, active comparator and placebo-controlled trial of a corticotropin-releasing factor receptor-1 antagonist in generalized anxiety disorder.

    Vladimir Coric;Howard H. Feldman;Dan A. Oren;Anantha Shekhar

  • LY354740, a potent group II metabotropic glutamate receptor agonist prevents lactate-induced panic-like response in panic-prone rats.

    Anantha Shekhar;S. R. Keim

  • Understanding and predicting suicidality using a combined genomic and clinical risk assessment approach

    A B Niculescu;D F Levey;P L Phalen;H Le-Niculescu

  • Steady state visual evoked potential abnormalities in schizophrenia.

    Giri P. Krishnan;Jenifer L. Vohs;William P. Hetrick;Christine A. Carroll

  • The amygdala, panic disorder, and cardiovascular responses.

    Anantha Shekhar;Tammy J. Sajdyk;Donald R. Gehlert;Donald G. Rainnie

  • Dorsomedial hypothalamic GABA dysfunction produces physiological arousal following sodium lactate infusions

    A. Shekhar;S.R. Keim;J.R. Simon;W.J. McBride

  • Blockade of GABAA receptors in the region of the anterior basolateral amygdala of rats elicits increases in heart rate and blood pressure.

    S. K. Sanders;Anantha Shekhar

  • Steady State and Induced Auditory Gamma Deficits in Schizophrenia

    Giri P. Krishnan;William P. Hetrick;C. A. Brenner;A. Shekhar

  • Stress and central Urocortin increase anxiety-like behavior in the social interaction test via the CRF1 receptor

    Donald R. Gehlert;Anantha Shekhar;S. Michelle Morin;Phillip A. Hipskind

  • Anxiety and motor performance in Parkinson's disease.

    Eric R. Siemers;Anantha Shekhar;Kimberly Quaid;Hal Dickson

Frequent Co-Authors

Philip L. Johnson
Philip L. Johnson Indiana University
William P. Hetrick
William P. Hetrick Indiana University
Andrew Goddard
Andrew Goddard University of California, San Francisco
Nicholas J. Schork
Nicholas J. Schork Translational Genomics Research Institute
John I. Nurnberger
John I. Nurnberger Indiana University
Anders Hay-Schmidt
Anders Hay-Schmidt University of Copenhagen
Fletcher A. White
Fletcher A. White Indiana University
Joseph E. Steinmetz
Joseph E. Steinmetz The Ohio State University
Yunlong Liu
Yunlong Liu Indiana University
William J. McBride
William J. McBride Indiana University

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