World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
60
Citations
11701
World Ranking
3174
National Ranking
49

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Mutation
  • Enzyme

His main research concerns Genetics, Mutation, Gene, Male infertility and Molecular biology. His Mutation research is multidisciplinary, incorporating elements of Cancer research, Respiratory chain, Pyruvate dehydrogenase complex and Candidate gene. In the subject of general Gene, his work in Intron, Haplotype and Founder effect is often linked to Cubilin, thereby combining diverse domains of study.

His Male infertility research is multidisciplinary, incorporating perspectives in Endocrinology, Y chromosome, Allele and Cystic fibrosis transmembrane conductance regulator. His Cystic fibrosis transmembrane conductance regulator research integrates issues from Congenital absence of the vas deferens, Heterozygote advantage, Genotype and Pathology. The concepts of his Molecular biology study are interwoven with issues in Gene mutation, Promoter, Exon, SOX9 and Binding site.

His most cited work include:

  • Mutations in the Cystic Fibrosis Gene in Patients with Congenital Absence of the Vas Deferens (795 citations)
  • Microsurgical epididymal sperm aspiration and intracytoplasmic sperm injection: a new effective approach to infertility as a result of congenital bilateral absence of the vas deferens * (287 citations)
  • The use of epididymal and testicular spermatozoa for intracytoplasmic sperm injection : the genetic implications for male infertility. (211 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Genetics, Gene, Molecular biology, Internal medicine and Endocrinology. Mutation, Exon, Mutation, Allele and Missense mutation are the core of his Genetics study. As a part of the same scientific family, Willy Lissens mostly works in the field of Mutation, focusing on Pyruvate dehydrogenase complex and, on occasion, Lactic acidosis.

His studies deal with areas such as Cystic fibrosis, Preimplantation genetic diagnosis and Genotype as well as Allele. His Gene study combines topics from a wide range of disciplines, such as Andrology, Spermatogenesis and Male infertility. His research on Molecular biology also deals with topics like

  • Polymerase chain reaction which intersects with area such as Embryo,
  • Respiratory chain and related Mitochondrial disease.

He most often published in these fields:

  • Genetics (38.46%)
  • Gene (21.74%)
  • Molecular biology (18.39%)

What were the highlights of his more recent work (between 2007-2019)?

  • Genetics (38.46%)
  • Gene (21.74%)
  • Mutation (15.38%)

In recent papers he was focusing on the following fields of study:

Genetics, Gene, Mutation, Male infertility and Mitochondrial DNA are his primary areas of study. His Gene research focuses on Spermatogenesis and how it relates to Maturation arrest, Meiosis and Cell biology. He has included themes like Intron and Exon in his Mutation study.

His Male infertility research incorporates elements of Meta-analysis, Y chromosome, X chromosome and Comparative genomic hybridization. His work carried out in the field of Mitochondrial DNA brings together such families of science as Molecular biology and Ion semiconductor sequencing. Respiratory chain is closely connected to Internal medicine in his research, which is encompassed under the umbrella topic of Mitochondrial disease.

Between 2007 and 2019, his most popular works were:

  • Genetic causes of spermatogenic failure (128 citations)
  • What about gr/gr deletions and male infertility? Systematic review and meta-analysis (63 citations)
  • Cancer predisposing missense and protein truncating BARD1 mutations in non-BRCA1 or BRCA2 breast cancer families. (58 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Mutation
  • Enzyme

Willy Lissens focuses on Genetics, Mutation, Male infertility, Internal medicine and Spermatogenesis. His is involved in several facets of Genetics study, as is seen by his studies on Gene, Allele, Missense mutation, Phenotype and Genotype. His work on Compound heterozygosity as part of general Allele study is frequently linked to Arylsulfatases, therefore connecting diverse disciplines of science.

His study on Point mutation is often connected to Polymicrogyria as part of broader study in Mutation. His Male infertility study combines topics in areas such as Y chromosome and X chromosome. Willy Lissens has researched Internal medicine in several fields, including Gastroenterology and Endocrinology.

Best Publications

  • Mutations in the Cystic Fibrosis Gene in Patients with Congenital Absence of the Vas Deferens

    Miguel Chillón;Teresa Casals;Bernard Mercier;Lluís Bassas

  • Microsurgical epididymal sperm aspiration and intracytoplasmic sperm injection: a new effective approach to infertility as a result of congenital bilateral absence of the vas deferens *

    Herman Tournaye;Paul Devroey;Jiaen Liu;Zsolt Nagy

  • The use of epididymal and testicular spermatozoa for intracytoplasmic sperm injection : the genetic implications for male infertility.

    Sherman J. Silber;Zsolt Nagy;Jian Liu;Herman Tournaye

  • Mutations in the gene encoding the latency-associated peptide of TGF-beta 1 cause Camurati-Engelmann disease.

    K. Janssens;R. Gershoni-Baruch;N. Guanabens;N. Migone

  • Mutations in the X-linked pyruvate dehydrogenase (E1) alpha subunit gene (PDHA1) in patients with a pyruvate dehydrogenase complex deficiency.

    Willy Lissens;Linda De Meirleir;Sara Seneca;Inge Liebaers

  • Serine protease activity and residual LEKTI expression determine phenotype in Netherton syndrome

    Jean Pierre Hachem;Fredrik Wagberg;Matthias Schmuth;Debra Crumrine

  • Respiratory chain complex V deficiency due to a mutation in the assembly gene ATP12

    L De Meirleir;S Seneca;W Lissens;I De Clercq

  • Genetic causes of spermatogenic failure

    Annelien Massart;Willy Lissens;Herman Tournaye;Katrien Stouffs

  • Is congenital bilateral absence of vas deferens a primary form of cystic fibrosis? Analyses of the CFTR gene in 67 patients

    B Mercier;C Verlingue;W Lissens;S J Silber

  • Loss of DNA-dependent dimerization of the transcription factor SOX9 as a cause for campomelic dysplasia.

    Elisabeth Sock;Roberta A. Pagon;Kathelijn Keymolen;Willy Lissens

  • Embryo implantation after biopsy of one or two cells from cleavage‐stage embryos with a view to preimplantation genetic diagnosis

    Hilde Van de Velde;Anick De Vos;Karen Sermon;Catherine Staessen

  • Study of DNA-methylation patterns at chromosome 15q11-q13 in children born after ICSI reveals no imprinting defects.

    Martina Manning;Willy Lissens;Maryse Bonduelle;Michel Camus

  • Bilateral striatal necrosis with a novel point mutation in the mitochondrial ATPase 6 gene

    Linda De Meirleir;Sara Seneca;Willy Lissens;Eric Schoentjes

  • Fluorescent PCR and automated fragment analysis for the clinical application of preimplantation genetic diagnosis of myotonic dystrophy (Steinert's disease).

    K Sermon;A De Vos;H Van de Velde;S Seneca

  • Birth after preimplantation diagnosis of the cystic fibrosis delta F508 mutation by polymerase chain reaction in human embryos resulting from intracytoplasmic sperm injection with epididymal sperm.

    Jiaen Liu;Willy Lissens;Sherman J. Silber;Paul Devroey

  • Cystic fibrosis and infertility caused by congenital bilateral absence of the vas deferens and related clinical entities

    Willy Lissens;Bernard Mercier;Herman Tournaye;Maryse Bonduelle

  • De novo Alu element insertions targeted to a sequence common to the BRCA1 and BRCA2 genes.

    Erik Teugels;Sylvia De Brakeleer;Guido Goelen;Willy Lissens

  • Possible role of USP26 in patients with severely impaired spermatogenesis.

    Katrien Stouffs;Willy Lissens;Herman Tournaye;Andre Van Steirteghem

  • Preimplantation genetic diagnosis: current status and new developments.

    Willy Lissens;Karen Sermon

  • Clinical and diagnostic characteristics of complex III deficiency due to mutations in the BCS1L gene.

    Linda De Meirleir;Sara Seneca;Eliane Damis;Brigitte Sepulchre

Frequent Co-Authors

Karen Sermon
Karen Sermon Vrije Universiteit Brussel
Herman Tournaye
Herman Tournaye Vrije Universiteit Brussel
Paul Devroey
Paul Devroey Vrije Universiteit Brussel
Robert Fagard
Robert Fagard KU Leuven
Nicolas Glansdorff
Nicolas Glansdorff Vrije Universiteit Brussel
Ron A. Wevers
Ron A. Wevers Radboud University
Sherman J. Silber
Sherman J. Silber Mount Sinai Morningside
A. Van Steirteghem
A. Van Steirteghem Vrije Universiteit Brussel
Claude Férec
Claude Férec University of Western Brittany

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