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Materials Science

D-Index
89
Citations
27637
World Ranking
1793
National Ranking
547

Research.com Recognitions

  • 2011 - Fellow of American Physical Society (APS) Citation For experimental explorations of molecular design parameters, kinetic effects, and rheological properties of peptide and block copolymer solution assembly
  • 2007 - John H. Dillon Medal, American Physical Society For advancing our understanding of the physics of assembly and chain conformation of synthetic polypeptides.

Overview

Darrin J. Pochan is affiliated with the University of Delaware in the United States. Their research spans multiple disciplines within materials science and biochemistry, genetics, and molecular biology, with a particular focus on biomaterials and molecular self-assembly.

The scientist's main fields of study include Materials Science and Biochemistry, Genetics and Molecular Biology. Subfields emphasize Biomaterials, Molecular Biology, Materials Chemistry, Organic Chemistry, and Biomedical Engineering. Key research topics covered in their work include Supramolecular Self-Assembly in Materials, Chemical Synthesis and Analysis, Advanced Polymer Synthesis and Characterization, Silk-based biomaterials and applications, Protein Structure and Dynamics, Hydrogels: synthesis, properties, applications, and Advanced biosensing and bioanalysis techniques.

Their publication record includes contributions to frequent venues such as Biomacromolecules, Faraday Discussions, Macromolecules, ACS Applied Materials & Interfaces, and Chemical Reviews. These journals reflect the interdisciplinary nature of their work, bridging chemistry, materials science, and biomedical applications.

Several recent papers highlight the breadth of Pochan's research:

  • "Peptide Design and Self-assembly into Targeted Nanostructure and Functional Materials" (2021), published in Chemical Reviews
  • "Rational Design of Bisphosphonate Lipid-like Materials for mRNA Delivery to the Bone Microenvironment" (2022), published in Journal of the American Chemical Society
  • "One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA" (2021), published in Journal of the American Chemical Society
  • "Introduction: Molecular Self-Assembly" (2021), published in Chemical Reviews
  • "Combinatorial design of siloxane-incorporated lipid nanoparticles augments intracellular processing for tissue-specific mRNA therapeutic delivery" (2024), published in Nature Nanotechnology

The scientist has collaborated frequently with other researchers, including Jeffery G. Saven, Christopher J. Kloxin, Tianren Zhang, Yao Tang, and Nairiti J. Sinha.

Darrin J. Pochan has been recognized within their field with awards such as the Fellow of the American Physical Society (APS) in 2011 for experimental work on molecular design parameters and rheological properties of peptide and block copolymer assembly. They also received the John H. Dillon Medal from the American Physical Society in 2007 for contributions to understanding the physics of assembly and chain conformation of synthetic polypeptides.

Best Publications

  • Synthesis and antibacterial properties of silver nanoparticles.

    C Baker;A Pradhan;L Pakstis;Darrin J Pochan

  • Block copolymer assembly via kinetic control.

    Honggang Cui;Zhiyun Chen;Sheng Zhong;Karen L. Wooley

  • Responsive Hydrogels from the Intramolecular Folding and Self-Assembly of a Designed Peptide

    Joel P Schneider;Darrin J Pochan;Bulent Ozbas;Karthikan Rajagopal

  • Rapidly recovering hydrogel scaffolds from self-assembling diblock copolypeptide amphiphiles

    Andrew P. Nowak;Victor Breedveld;Lisa Pakstis;Bulent Ozbas

  • Toroidal Triblock Copolymer Assemblies

    Darrin J. Pochan;Zhiyun Chen;Honggang Cui;Kelly Hales

  • Rheological properties of peptide-based hydrogels for biomedical and other applications.

    Congqi Yan;Darrin J. Pochan

  • Stimuli-responsive polypeptide vesicles by conformation-specific assembly.

    Enrico G. Bellomo;Michael D. Wyrsta;Lisa Pakstis;Darrin J. Pochan

  • Controlling hydrogelation kinetics by peptide design for three-dimensional encapsulation and injectable delivery of cells

    Lisa Haines-Butterick;Karthikan Rajagopal;Monica Branco;Daphne Salick

  • Salt-Triggered Peptide Folding and Consequent Self-Assembly into Hydrogels with Tunable Modulus

    Bulent Ozbas;Juliana Kretsinger;Karthikan Rajagopal;Joel P. Schneider

  • Tailored Assemblies of Block Copolymers in Solution: It Is All about the Process

    Ryan C. Hayward;Darrin J. Pochan

  • Thermally reversible hydrogels via intramolecular folding and consequent self-assembly of a de novo designed peptide.

    Darrin J Pochan;Joel P Schneider;Juliana Kretsinger;Bulent Ozbas

  • Encapsulation of curcumin in self-assembling peptide hydrogels as injectable drug delivery vehicles

    Aysegul Altunbas;Seung Joon Lee;Sigrid A. Rajasekaran;Joel P. Schneider

  • Poly (l-Lactic Acid)/Layered Silicate Nanocomposite: Fabrication, Characterization, and Properties

    Vahik Krikorian;Darrin J. Pochan

  • Charged polypeptide Vesicles with Controllable Diameter

    Eric P. Holowka;Darrin J. Pochan;Timothy J. Deming

  • Light-activated hydrogel formation via the triggered folding and self-assembly of a designed peptide.

    Lisa A. Haines;Karthikan Rajagopal;Bulent Ozbas;Daphne A. Salick

  • Injectable solid hydrogel: mechanism of shear-thinning and immediate recovery of injectable β-hairpin peptide hydrogels

    Congqi Yan;Aysegul Altunbas;Tuna Yucel;Radhika P. Nagarkar

  • Modular Synthesis of Amphiphilic Janus Glycodendrimers and Their Self-Assembly into Glycodendrimersomes and Other Complex Architectures with Bioactivity to Biomedically Relevant Lectins

    Virgil Percec;Pawaret Leowanawat;Hao Jan Sun;Oleg Kulikov

  • Inherent Antibacterial Activity of a Peptide-Based β-Hairpin Hydrogel

    Daphne A. Salick;Juliana K. Kretsinger;Darrin J. Pochan;Joel P. Schneider

  • Polymer Nanocomposites for Biomedical Applications

    Rohan A. Hule;Darrin J. Pochan

  • Antibacterial Properties of Silver‐Doped Titania

    J. Thiel;L. Pakstis;S. Buzby;M. Raffi;M. Raffi

Frequent Co-Authors

Joel P. Schneider
Joel P. Schneider National Institutes of Health
Karen L. Wooley
Karen L. Wooley Texas A&M University
Timothy J. Deming
Timothy J. Deming University of California, Los Angeles
Honggang Cui
Honggang Cui Johns Hopkins University
Jeffery G. Saven
Jeffery G. Saven University of Pennsylvania
Kristi L. Kiick
Kristi L. Kiick University of Delaware
Jimmy W. Mays
Jimmy W. Mays University of Tennessee at Knoxville
Xinqiao Jia
Xinqiao Jia University of Delaware
Samuel P. Gido
Samuel P. Gido University of Massachusetts Amherst
Virgil Percec
Virgil Percec University of Pennsylvania

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