What is she best known for?
The fields of study she is best known for:
Her primary scientific interests are in Gene expression, Gene expression profiling, Gene, Computational biology and DNA microarray.
As part of her inquiry into Genetics and Biochemistry, Cynthia A. Afshari is doing Gene expression research.
Her studies in Gene expression profiling integrate themes in fields like Microarray analysis techniques, Saccharomyces cerevisiae and Pharmacology.
Her Computational biology research is multidisciplinary, incorporating elements of Design of experiments, Data mining, Mixed model and Two Color Microarray.
Her research investigates the link between DNA microarray and topics such as Toxicology that cross with problems in Gene chip analysis, Carcinogen and Emerging technologies.
Her CDNA Microarrays study combines topics in areas such as Toxicogenomics and Genomics.
Her most cited work include:
- Assessing Gene Significance from cDNA Microarray Expression Data via Mixed Models (1058 citations)
- Microarrays and toxicology: the advent of toxicogenomics. (570 citations)
- Diverse Roles of the Nuclear Orphan Receptor CAR in Regulating Hepatic Genes in Response to Phenobarbital (421 citations)
What are the main themes of her work throughout her whole career to date?
Cynthia A. Afshari spends much of her time researching Gene expression, Gene, Gene expression profiling, Molecular biology and Genetics.
In her study, which falls under the umbrella issue of Gene expression, Cancer research is strongly linked to Regulation of gene expression.
Her work on Complementary DNA as part of general Gene study is frequently linked to Enzyme inducer, bridging the gap between disciplines.
The various areas that Cynthia A. Afshari examines in her Gene expression profiling study include Gene chip analysis, DNA microarray, Microarray analysis techniques and Signal transduction.
Her biological study spans a wide range of topics, including Cell culture, Promoter, Telomerase reverse transcriptase and Cell biology.
Cynthia A. Afshari has included themes like Toxicity, Bioinformatics and Genomics in her Toxicogenomics study.
She most often published in these fields:
- Gene expression (21.87%)
- Gene (19.79%)
- Gene expression profiling (19.79%)
What were the highlights of her more recent work (between 2008-2016)?
- Pharmacology (10.42%)
- Hepatocyte (4.17%)
- Receptor (3.12%)
In recent papers she was focusing on the following fields of study:
Her scientific interests lie mostly in Pharmacology, Hepatocyte, Receptor, Cell culture and Bioinformatics.
She is studying Drug development, which is a component of Pharmacology.
Her Hepatocyte research incorporates themes from Liver injury, Transporter and Bile acid.
Her Receptor research integrates issues from Tocilizumab, Interleukin 6, Area under the curve and In vitro.
Her Cell culture study focuses on Viability assay in particular.
Her research links Toxicology with Bioinformatics.
Between 2008 and 2016, her most popular works were:
- Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. (231 citations)
- A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. (139 citations)
- The Evolution of Bioinformatics in Toxicology: Advancing Toxicogenomics (99 citations)
In her most recent research, the most cited papers focused on:
Cynthia A. Afshari mainly investigates Transporter, Liver injury, Bile acid, Hepatocyte and Pharmacology.
In the subject of general Transporter, her work in Multidrug resistance-associated protein 2, Membrane transport protein and ATP-binding cassette transporter is often linked to Progressive familial intrahepatic cholestasis, thereby combining diverse domains of study.
Her Liver injury research incorporates elements of Efflux, Drug development and Bile Salt Export Pump.
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