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Constantin N. Baxevanis

Constantin N. Baxevanis

D-Index & Metrics

Immunology

D-Index
53
Citations
10469
World Ranking
3974
National Ranking
8

Overview

Constantin N. Baxevanis is affiliated with St Savas Hospital in Greece and has an extensive publication record focused primarily on medicine, immunology, and oncology. Their research portfolio includes significant contributions to the fields of cancer immunotherapy, immune response mechanisms, and biomarkers relevant to cancer diagnostics and treatment.

The scientist's work spans various interconnected subfields, notably oncology, immunology, pulmonary and respiratory medicine, cancer research, and molecular biology. They have published extensively on topics such as cancer immunotherapy and biomarkers, immunotherapy and immune responses, prostate cancer treatment and research, cancer genomics and diagnostics, ferroptosis and cancer prognosis, immune cell function and interaction, and cancer-related molecular mechanisms research.

Among their recent publications are the following papers:

  • "Prospective, randomized, single-blinded, multi-center phase II trial of two HER2 peptide vaccines, GP2 and AE37, in breast cancer patients to prevent recurrence," 2020, Breast Cancer Research and Treatment
  • "Promising Biomarkers in Head and Neck Cancer: The Most Clinically Important miRNAs," 2022, International Journal of Molecular Sciences
  • "DNA Damage Response Mechanisms in Head and Neck Cancer: Significant Implications for Therapy and Survival," 2023, International Journal of Molecular Sciences
  • "Circulating Plasma Cell-free DNA (cfDNA) as a Predictive Biomarker for Radiotherapy: Results from a Prospective Trial in Head and Neck Cancer," 2023, Cancer Diagnosis & Prognosis
  • "Immune Checkpoint Inhibitors in Cancer Therapy-How Can We Improve Clinical Benefits?" 2023, Cancers

The body of work published by Constantin N. Baxevanis appears prominently in several scientific venues. Key journals in which the scientist has published multiple articles include:

  • Cancers
  • Onco
  • International Journal of Molecular Sciences
  • Breast Cancer Research and Treatment
  • Cancer Diagnosis & Prognosis

Collaboration forms a significant part of their research activity. Frequent coauthors include:

  • Sotirios P. Fortis
  • Maria Goulielmaki
  • Angelos D. Gritzapis
  • Savvas Stokidis
  • Panagiota Batsaki

Their scientific contributions center around advancing the understanding of immunotherapy and biomarker development in cancer treatment, with a notable focus on translating molecular and genomic discoveries into clinical applications. The continued exploration of mechanisms such as immune checkpoint inhibition and DNA damage response highlights an ongoing engagement with therapeutic innovation and cancer patient outcomes.

Best Publications

  • Interactions between human mesenchymal stem cells and natural killer cells.

    Panagiota A. Sotiropoulou;Sonia A. Perez;Angelos D. Gritzapis;Constantin N. Baxevanis

  • Characterization of the optimal culture conditions for clinical scale production of human mesenchymal stem cells.

    Panagiota A. Sotiropoulou;Sonia A. Perez;Maria Salagianni;Constantin N. Baxevanis

  • The traditional and a new version of the mouse H-2 complex

    Jan Klein;Antonio JuretiĆ;Antonio JuretiĆ;Constantin N. Baxevanis;Zoltan A. Nagy

  • An improved fluorescence assay for the determination of lymphocyte-mediated cytotoxicity using flow cytometry.

    Nikolaos G. Papadopoulos;George V.Z. Dedoussis;Gregory Spanakos;Angelos D. Gritzapis

  • A phase I trial of adoptive transfer of allogeneic natural killer cells in patients with advanced non-small cell lung cancer

    Eleni G. Iliopoulou;Panteleimon Kountourakis;Michalis V. Karamouzis;Dimitrios Doufexis

  • Cytokine serum levels, autologous mixed lymphocyte reaction and surface marker analysis in never medicated and chronically medicated schizophrenic patients.

    St. Theodoropoulou;G. Spanakos;C.N. Baxevanis;M. Economou

  • Effects of donor age, gender, and in vitro cellular aging on the phenotypic, functional, and molecular characteristics of mouse bone marrow-derived mesenchymal stem cells.

    Olga Katsara;Louisa G. Mahaira;Eleni G. Iliopoulou;Ardiana Moustaki

  • Tumor-specific CD4+ T lymphocytes from cancer patients are required for optimal induction of cytotoxic T cells against the autologous tumor.

    Constantin N. Baxevanis;Ioannis F. Voutsas;Ourania E. Tsitsilonis;Angelos D. Gritzapis

  • Ia Antigens as Restriction Molecules in Ir-Gene Controlled T-Cell Proliferation

    Zoltan A. Nagy;Constantin N. Baxevanis;Norihisa Ishii;Jan Klein

  • Combinatorial treatments including vaccines, chemotherapy and monoclonal antibodies for cancer therapy

    Constantin N. Baxevanis;Sonia A. Perez;Michael Papamichail

  • Natural killer lymphocytes: biology, development, and function.

    Michael Papamichail;Sonia A. Perez;Angelos D. Gritzapis;Constantin N. Baxevanis

  • Cancer immunotherapy

    Unknown

  • Elevated prostaglandin E2 production by monocytes is responsible for the depressed levels of natural killer and lymphokine-activated killer cell function in patients with breast cancer

    Constantin N. Baxevanis;George J. Reclos;Angelos D. Gritzapis;George V. Z. Dedousis

  • A new era in anticancer peptide vaccines

    Sonia A. Perez;Eric von Hofe;Nikoletta L. Kallinteris;Angelos D. Gritzapis

  • Tumor specific cytolysis by tumor infiltrating lymphocytes in breast cancer

    Constantin N. Baxevanis;George V. Z. Dedoussis;Nikolaos G. Papadopoulos;Ioannis Missitzis

  • The prognostic significance of peritumoral tertiary lymphoid structures in breast cancer.

    Michael Sofopoulos;Sotirios P Fortis;Christoforos K Vaxevanis;Nectaria N Sotiriadou

  • Cell culture medium composition and translational adult bone marrow-derived stem cell research.

    Panagiota A. Sotiropoulou;Sonia A. Perez;Maria Salagianni;Constantin N. Baxevanis

  • CD4+CD25+ regulatory T-cell frequency in HER-2/neu (HER)-positive and HER-negative advanced-stage breast cancer patients.

    Sonia A. Perez;Michael V. Karamouzis;Dimosthenes V. Skarlos;Alexandros Ardavanis

  • The balance between breast cancer and the immune system: Challenges for prognosis and clinical benefit from immunotherapies.

    Constantin N. Baxevanis;Sotirios P. Fortis;Sonia A. Perez

  • Abnormal cytokine serum levels correlate with impaired cellular immune responses after surgery.

    Constantin N. Baxevanis;Konstantinos Papilas;George V.Z. Dedoussis;Theodor Pavlis

  • Compromised anti-tumor responses in tumor necrosis factor-α knockout mice

    Constantin N. Baxevanis;Ioannis F. Voutsas;Ourania E. Tsitsilonis;Marinos L. Tsiatas

  • Immunogenic HER-2/neu peptides as tumor vaccines

    Constantin N. Baxevanis;Nectaria N. Sotiriadou;Angelos D. Gritzapis;Panagiota A. Sotiropoulou

  • Peptide HER2(776-788) represents a naturally processed broad MHC class II-restricted T cell epitope.

    R Sotiriadou;S A Perez;A D Gritzapis;Panagiota Sotiropoulou

  • Immunobiology of HER-2/neu oncoprotein and its potential application in cancer immunotherapy

    Constantin N. Baxevanis;Panagiota A. Sotiropoulou;Nectaria N. Sotiriadou;Michael Papamichail

Frequent Co-Authors

Michael Papamichail
Michael Papamichail St Savas Hospital
Elizabeth A. Mittendorf
Elizabeth A. Mittendorf Brigham and Women's Hospital
George Dedoussis
George Dedoussis Harokopio University
Nikolaos G. Papadopoulos
Nikolaos G. Papadopoulos National and Kapodistrian University of Athens
Graham Pawelec
Graham Pawelec University of Tübingen
Wolfgang Voelter
Wolfgang Voelter University of Tübingen
George C. Tsokos
George C. Tsokos Harvard Medical School
Dimitris Thanos
Dimitris Thanos Academy of Athens
Hubert Kalbacher
Hubert Kalbacher University of Tübingen
Federica Cavallo
Federica Cavallo University of Turin

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