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D-Index & Metrics

Neuroscience

D-Index
44
Citations
7718
World Ranking
7157
National Ranking
3099

Overview

Andrew Escayg is affiliated with Emory University in the United States. Their research primarily revolves around neuroscience with significant intersections in biochemistry, genetics, molecular biology, and medicine.

The main fields of study addressed in their work include:

  • Neuroscience
  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these broad areas, Escayg's research focuses on various subfields such as:

  • Cellular and Molecular Neuroscience
  • Molecular Biology
  • Genetics
  • Psychiatry and Mental Health
  • Neurology

The subjects covered in their publications span multiple key topics related to brain function and disorders, specifically:

  • Neuroscience and Neuropharmacology Research
  • Epilepsy Research and Treatment
  • Genetics and Neurodevelopmental Disorders
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Neuroendocrine Regulation and Behavior
  • Neurogenesis and Neuroplasticity Mechanisms
  • Cannabis and Cannabinoid Research

Andrew Escayg has published in several scientific venues, commonly contributing to:

  • Frontiers in Pharmacology
  • Neurobiology of Disease
  • Experimental Neurology
  • Neuropsychopharmacology
  • Neuropharmacology

Frequent coauthors collaborating with Escayg include:

  • Jennifer C. Wong
  • Lindsey Shapiro
  • Jacquelyn T. Thelin
  • Martin J. D'Souza
  • Kevin S. Murnane

Selected recent publications illustrate the focus of Escayg's research:

  • Extracellular vesicles in the treatment of neurological disorders, 2021, Neurobiology of Disease
  • Nanoparticle encapsulated oxytocin increases resistance to induced seizures and restores social behavior in Scn1a-derived epilepsy, 2020, Neurobiology of Disease
  • Mice lacking full length Adgrb1 (Bai1) exhibit social deficits, increased seizure susceptibility, and altered brain development, 2022, Experimental Neurology
  • Autistic-like behavior, spontaneous seizures, and increased neuronal excitability in a Scn8a mouse model, 2021, Neuropsychopharmacology
  • Allosteric modulation of the cannabinoid 2 receptor confers seizure resistance in mice, 2021, Neuropharmacology

Best Publications

  • Mutations of SCN1A, encoding a neuronal sodium channel, in two families with GEFS+2.

    Andrew Escayg;Bryan T. MacDonald;Miriam H. Meisler;Stéphanie Baulac

  • Coding and Noncoding Variation of the Human Calcium-Channel β4-Subunit Gene CACNB4 in Patients with Idiopathic Generalized Epilepsy and Episodic Ataxia

    Andrew Escayg;Michel De Waard;David D. Lee;Delphine Bichet

  • Sodium channel SCN1A and epilepsy: mutations and mechanisms.

    Andrew Escayg;Alan L. Goldin

  • A novel SCN1A mutation associated with generalized epilepsy with febrile seizures plus--and prevalence of variants in patients with epilepsy.

    Andrew Escayg;Armin Heils;Bryan T. MacDonald;Karsten Haug

  • Sodium channels SCN1A, SCN2A and SCN3A in familial autism.

    L A Weiss;A Escayg;J A Kearney;M Trudeau

  • Altered Function of the SCN1A Voltage-gated Sodium Channel Leads to γ-Aminobutyric Acid-ergic (GABAergic) Interneuron Abnormalities

    Melinda S. Martin;Karoni Dutt;Ligia Assumpção Papale;Ligia Assumpção Papale;Celine M. Dube

  • The voltage-gated sodium channel Scn8a is a genetic modifier of severe myoclonic epilepsy of infancy.

    Melinda S. Martin;Bin Tang;Ligia A. Papale;Frank H. Yu

  • Functional Effects of Two Voltage-Gated Sodium Channel Mutations That Cause Generalized Epilepsy with Febrile Seizures Plus Type 2

    Jay Spampanato;Andrew Escayg;Miriam H. Meisler;Alan L. Goldin

  • A Novel Epilepsy Mutation in the Sodium Channel SCN1A Identifies a Cytoplasmic Domain for β Subunit Interaction

    J. Spampanato;J. A. Kearney;G. de Haan;D. P. McEwen

  • Identification of epilepsy genes in human and mouse.

    Miriam H. Meisler;Jennifer Kearney;Ruth Ottman;Andrew Escayg

  • Impaired Action Potential Initiation in GABAergic Interneurons Causes Hyperexcitable Networks in an Epileptic Mouse Model Carrying a Human NaV1.1 Mutation

    Ulrike B.S. Hedrich;Camille Liautard;Daniel Kirschenbaum;Martin Pofahl

  • Preferential inactivation of Scn1a in parvalbumin interneurons increases seizure susceptibility.

    Stacey B. Dutton;Christopher D. Makinson;Ligia A. Papale;Anupama Shankar

  • Heterozygous mutations of the voltage-gated sodium channel SCN8A are associated with spike-wave discharges and absence epilepsy in mice

    Ligia Assumpção Papale;Barbara Beyer;Julie M. Jones;Lisa M. Sharkey

  • Generalized epilepsy with febrile seizures plus type 2 mutation W1204R alters voltage-dependent gating of Nav1.1 sodium channels

    J. Spampanato;A. Escayg;M.H. Meisler;A.L. Goldin

  • An Epilepsy Mutation in the Sodium Channel SCN1A That Decreases Channel Excitability

    Arthur J. Barela;Salina P. Waddy;Jay G. Lickfett;Jessica Hunter

  • Regulation of Thalamic and Cortical Network Synchrony by Scn8a.

    Christopher D. Makinson;Brian S. Tanaka;Jordan M. Sorokin;Jennifer C. Wong

  • A BAC transgenic mouse model reveals neuron subtype-specific effects of a Generalized Epilepsy with Febrile Seizures Plus (GEFS+) mutation

    Bin Tang;Karoni Dutt;Ligia Papale;Raffaella Rusconi

  • Migrainous vertigo: mutation analysis of the candidate genes CACNA1A, ATP1A2, SCN1A, and CACNB4.

    Michael Von Brevern;Nga Ta;Anupama Shankar;Anna Wiste

  • Diagnostic Yield From 339 Epilepsy Patients Screened on a Clinical Gene Panel

    Kameryn M. Butler;Cristina da Silva;John J. Alexander;Madhuri Hegde

  • Neuronal voltage-gated ion channels are genetic modifiers of generalized epilepsy with febrile seizures plus.

    Nicole A. Hawkins;Melinda S. Martin;Wayne N. Frankel;Jennifer A. Kearney

  • De novo variants in GABRA2 and GABRA5 alter receptor function and contribute to early-onset epilepsy

    Kameryn M Butler;Olivia A Moody;Elisabeth Schuler;Jason Coryell

Frequent Co-Authors

Alan L. Goldin
Alan L. Goldin University of California, Irvine
Miriam H. Meisler
Miriam H. Meisler University of Michigan–Ann Arbor
Jennifer A. Kearney
Jennifer A. Kearney Northwestern University
Thomas Sander
Thomas Sander University of Cologne
Holger Lerche
Holger Lerche University of Tübingen
Heinz Beck
Heinz Beck University of Bonn
Ulrich Stephani
Ulrich Stephani Kiel University
Wayne N. Frankel
Wayne N. Frankel Columbia University
Céline Dubé
Céline Dubé University of California, Irvine
Tallie Z. Baram
Tallie Z. Baram University of California, Irvine

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