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Hubert Kalbacher

Hubert Kalbacher

D-Index & Metrics

Biology and Biochemistry

D-Index
79
Citations
22729
World Ranking
4309
National Ranking
321

Overview

Hubert Kalbacher is affiliated with the University of Tübingen in Germany. Their research spans multiple interconnected fields within biomedical science, with a primary focus on medicine and biochemistry, genetics, and molecular biology. The work covers several subfields, including molecular biology, infectious diseases, pulmonary and respiratory medicine, immunology, and epidemiology.

The main topics of Kalbacher's research include:

  • COVID-19 clinical research studies
  • Neutrophil, myeloperoxidase, and oxidative mechanisms
  • SARS-CoV-2 and COVID-19 research
  • Heat shock proteins research
  • Neonatal respiratory health research
  • Mitochondrial function and pathology
  • ATP synthase and ATPases research

Hubert Kalbacher's recent publications demonstrate a focus on immunology and infectious disease mechanisms, particularly related to inflammation and viral pathogens. Selected recent papers include:

  • Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psoriasis, 2020, Nature Communications
  • Immunogenic Cell Death, DAMPs and Prothymosin α as a Putative Anticancer Immune Response Biomarker, 2022, Cells
  • BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity, 2021, The Journal of Experimental Medicine
  • Neutrophil Elastase and Proteinase 3 Cleavage Sites Are Adjacent to the Polybasic Sequence within the Proteolytic Sensitive Activation Loop of the SARS-CoV-2 Spike Protein, 2021, ACS Omega
  • Proteasuria in nephrotic syndrome-quantification and proteomic profiling, 2020, Journal of Proteomics

Kalbacher has frequently collaborated with several coauthors, indicating sustained research partnerships. Notable frequent coauthors include Boris Maček, Timo Burster, Matthias Wörn, Andreas L. Birkenfeld, and Ferruh Artunç.

The main publication venues for Kalbacher's work are diverse but include multiple contributions to bioRxiv (Cold Spring Harbor Laboratory), Current Medicinal Chemistry, and Molecules. Additional publication venues include Nature Communications and Cells.

Best Publications

  • Inactivation of the dlt operon in Staphylococcus aureus confers sensitivity to defensins, protegrins, and other antimicrobial peptides.

    Andreas Peschel;Michael Otto;Ralph W. Jack;Hubert Kalbacher

  • Staphylococcus aureus resistance to human defensins and evasion of neutrophil killing via the novel virulence factor MprF is based on modification of membrane lipids with L-lysine

    Andreas Peschel;Andreas Peschel;Ralph W. Jack;Michael Otto;L. Vincent Collins

  • Human commensals producing a novel antibiotic impair pathogen colonization

    Alexander Zipperer;Martin C. Konnerth;Claudia Laux;Anne Berscheid

  • Dermcidin: a novel human antibiotic peptide secreted by sweat glands.

    Birgit Schittek;Rainer Hipfel;Birgit Sauer;Jürgen Bauer

  • Autophagy promotes MHC class II presentation of peptides from intracellular source proteins

    Jörn Dengjel;Oliver Schoor;Rainer Fischer;Michael Reich

  • Methylation determines fibroblast activation and fibrogenesis in the kidney

    Wibke Bechtel;Scott McGoohan;Elisabeth M Zeisberg;Gerhard A Müller

  • Role of teichoic acids in Staphylococcus aureus nasal colonization, a major risk factor in nosocomial infections

    Christopher Weidenmaier;John F Kokai-Kun;Sascha A Kristian;Tanya Chanturiya

  • De novo lipogenesis in health and disease.

    Fatima Ameer;Lisa Scandiuzzi;Shahida Hasnain;Hubert Kalbacher

  • Claudin-1 and claudin-5 expression and tight junction morphology are altered in blood vessels of human glioblastoma multiforme

    S Liebner;A Fischmann;G Rascher;F Duffner

  • The bacterial defensin resistance protein MprF consists of separable domains for lipid lysinylation and antimicrobial peptide repulsion.

    Christoph M. Ernst;Petra Staubitz;Nagendra N. Mishra;Soo Jin Yang

  • Deficiency of dermcidin-derived antimicrobial peptides in sweat of patients with atopic dermatitis correlates with an impaired innate defense of human skin in vivo

    Siegbert Rieg;Heiko Steffen;Silke Seeber;Andreas Humeny

  • Two new proteases in the MHC class I processing pathway

    Lars Stoltze;Markus Schirle;Gerold Schwarz;Christian Schröter

  • The rice immune receptor XA21 recognizes a tyrosine-sulfated protein from a Gram-negative bacterium

    Rory N Pruitt;Benjamin Schwessinger;Anna Joe;Nicholas Thomas

  • Ligand motifs of HLA-DRB5*0101 and DRB1*1501 molecules delineated from self-peptides.

    A B Vogt;H Kropshofer;H Kalbacher;M Kalbus

  • Cathepsin D: a cellular roadmap.

    Nousheen Zaidi;Andreas Maurer;Sebastian Nieke;Hubert Kalbacher

  • Correlation of tight junction morphology with the expression of tight junction proteins in blood-brain barrier endothelial cells.

    Stefan Liebner;Uwe Kniesel;Uwe Kniesel;Hubert Kalbacher;Hartwig Wolburg

  • PENICILLOYL PEPTIDES ARE RECOGNIZED AS T CELL ANTIGENIC DETERMINANTS IN PENICILLIN ALLERGY

    Elisabetta Padovan;Tanja Bauer;Marie Marte Tongio;Hubert Kalbacher

  • The Tarantula Toxin Psalmotoxin 1 Inhibits Acid-sensing Ion Channel (ASIC) 1a by Increasing Its Apparent H+ Affinity

    Xuanmao Chen;Xuanmao Chen;Hubert Kalbacher;Stefan Gründer;Stefan Gründer

  • Biomimetic macroporous PEG hydrogels as 3D scaffolds for the multiplication of human hematopoietic stem and progenitor cells

    Annamarija Raic;Annamarija Raic;Lisa Rödling;Hubert Kalbacher;Cornelia Lee-Thedieck

  • Characterization of the ubiquitin-proteasome system in bortezomib-adapted cells.

    T Rückrich;M Kraus;J Gogel;A Beck

Frequent Co-Authors

Wolfgang Voelter
Wolfgang Voelter University of Tübingen
Christoph Driessen
Christoph Driessen University of St. Gallen
Claudia A. Müller
Claudia A. Müller University of Tübingen
Stefan Stevanovic
Stefan Stevanovic University of Tübingen
Birgit Schittek
Birgit Schittek University of Tübingen
Graham Pawelec
Graham Pawelec University of Tübingen
Bernhard O. Boehm
Bernhard O. Boehm Nanyang Technological University
Andreas Peschel
Andreas Peschel University of Tübingen
Claus Garbe
Claus Garbe University of Tübingen
Günther Jung
Günther Jung University of Tübingen

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