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D-Index & Metrics

Biology and Biochemistry

D-Index
60
Citations
12600
World Ranking
11976
National Ranking
851

Overview

Birgit Schittek is affiliated with the University of Tübingen in Germany.

Their research spans several main fields including Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology. Within these areas, their subfields of study comprise Immunology, Molecular Biology, Dermatology, Oncology, and Microbiology.

Key topics addressed in Schittek's work focus on Neutrophil, Myeloperoxidase and Oxidative Mechanisms, Immune Response and Inflammation, Dermatology and Skin Diseases, Antimicrobial Peptides and Activities, Heat shock proteins research, RNA Research and Splicing, and Inflammasome and immune disorders.

Recent scientific papers published include:

  • Tumour Progression Stage-Dependent Secretion of YB-1 Stimulates Melanoma Cell Migration and Invasion (2020, Cancers)
  • The epidermal lipid barrier in microbiome-skin interaction (2023, Trends in Microbiology)
  • Beneficial effects of coagulase-negative Staphylococci on Staphylococcus aureus skin colonization (2021, Experimental Dermatology)
  • Targeting Rad51 as a strategy for the treatment of melanoma cells resistant to MAPK pathway inhibition (2020, Cell Death and Disease)
  • Blocking Y-Box Binding Protein-1 through Simultaneous Targeting of PI3K and MAPK in Triple Negative Breast Cancers (2020, Cancers)

Frequent co-authors collaborating with Schittek are:

  • Jule Focken
  • Birgit Sauer
  • Tobias Sinnberg
  • Corinna Kosnopfel
  • Jasmin Scheurer

Schittek has contributed to multiple publication venues, notably:

  • Experimental Dermatology
  • Frontiers in Immunology
  • Journal of Investigative Dermatology
  • Cancers
  • bioRxiv (Cold Spring Harbor Laboratory)

Best Publications

  • Human commensals producing a novel antibiotic impair pathogen colonization

    Alexander Zipperer;Martin C. Konnerth;Claudia Laux;Anne Berscheid

  • Dermcidin: a novel human antibiotic peptide secreted by sweat glands.

    Birgit Schittek;Rainer Hipfel;Birgit Sauer;Jürgen Bauer

  • Maintenance of B-cell memory by long-lived cells generated from proliferating precursors

    Birgit Schittek;Klaus Rajewsky

  • Metastatic pathways and time courses in the orderly progression of cutaneous melanoma.

    F. Meier;S. Will;U. Ellwanger;B. Schlagenhauff

  • Cathelicidin anti-microbial peptide expression in sweat, an innate defense system for the skin.

    Masamoto Murakami;Takaaki Ohtake;Robert A. Dorschner;Richard L. Gallo

  • Prospective Evaluation of a Follow-Up Schedule in Cutaneous Melanoma Patients: Recommendations for an Effective Follow-Up Strategy

    Claus Garbe;Andrena Paul;Hanna Kohler-Späth;Ulf Ellwanger

  • Deficiency of dermcidin-derived antimicrobial peptides in sweat of patients with atopic dermatitis correlates with an impaired innate defense of human skin in vivo

    Siegbert Rieg;Heiko Steffen;Silke Seeber;Andreas Humeny

  • The RAS/RAF/MEK/ERK and PI3K/AKT signaling pathways present molecular targets for the effective treatment of advanced melanoma.

    Friedegund Meier;Birgit Schittek;Silke Busch;Claus Garbe

  • The natural course of cutaneous melanoma

    Ulrike Leiter;Friedegund Meier;Birgit Schittek;Claus Garbe

  • Skin Commensals Amplify the Innate Immune Response to Pathogens by Activation of Distinct Signaling Pathways

    Ines Wanke;Heiko Steffen;Christina Christ;Bernhard Krismer

  • Lysis of a broad range of epithelial tumour cells by human gamma delta T cells: Involvement of NKG2D ligands and T-cell receptor- versus NKG2D-dependent recognition

    P. Wrobel;H. Shojaei;B. Schittek;F. Gieseler

  • Biological functions of casein kinase 1 isoforms and putative roles in tumorigenesis.

    Birgit Schittek;Tobias Sinnberg

  • Examination of Regional Lymph Nodes by Sentinel Node Biopsy and Molecular Analysis Provides New Staging Facilities in Primary Cutaneous Melanoma

    Hans-Juergen Blaheta;Ulf Ellwanger;Birgit Schittek;Evelyn Maczey

  • HLA-A2 Restricted, Melanocyte-Specific CD8+ T Lymphocytes Detected in Vitiligo Patients are Related to Disease Activity and are Predominantly Directed Against MelanA/MART1

    Karl Sebastian Lang;Constanze Charlotte Caroli;Alexandra Muhm;Dorothee Wernet

  • Molecular events in melanoma development and progression.

    F Meier;K Satyamoorthy;M Nesbit;M Y Hsu

  • Combined inhibition of MAPK and mTOR signaling inhibits growth, induces cell death, and abrogates invasive growth of melanoma cells.

    Konstantinos G. Lasithiotakis;Tobias W. Sinnberg;Birgit Schittek;Keith T. Flaherty

  • Dermcidin is constitutively produced by eccrine sweat glands and is not induced in epidermal cells under inflammatory skin conditions.

    S. Rieg;C. Garbe;B. Sauer;H. Kalbacher

  • Inhibition of PI3K-AKT-mTOR signaling sensitizes melanoma cells to cisplatin and temozolomide.

    Tobias Sinnberg;Konstantinos Lasithiotakis;Heike Niessner;Birgit Schittek

  • miR-137 Inhibits the Invasion of Melanoma Cells through Downregulation of Multiple Oncogenic Target Genes

    Chonglin Luo;Paul W. Tetteh;Patrick R. Merz;Elke Dickes

  • The role of antimicrobial peptides in human skin and in skin infectious diseases.

    Birgit Schittek;Maren Paulmann;Ilknur Senyurek;Heiko Steffen

Frequent Co-Authors

Claus Garbe
Claus Garbe University of Tübingen
Hubert Kalbacher
Hubert Kalbacher University of Tübingen
Andreas Peschel
Andreas Peschel University of Tübingen
Martin Schaller
Martin Schaller University of Tübingen
Keith T. Flaherty
Keith T. Flaherty Harvard University
Friedrich Götz
Friedrich Götz University of Tübingen
Tilo Biedermann
Tilo Biedermann Technical University of Munich
Stefan Stevanovic
Stefan Stevanovic University of Tübingen
Klaus Rajewsky
Klaus Rajewsky Max Delbrück Center for Molecular Medicine
Dirk Schadendorf
Dirk Schadendorf University of Duisburg-Essen

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