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Molecular Biology

D-Index
47
Citations
5837
World Ranking
2762
National Ranking
1329

Overview

Chung Ming Tse is affiliated with Johns Hopkins University School of Medicine in the United States. Their research broadly spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a particular focus on Molecular Biology, Oncology, Surgery, Genetics, and Gastroenterology as key subfields.

The scientist's work centers on several main topics including Ion Transport and Channel Regulation, Drug Transport and Resistance Mechanisms, Digestive System and Related Health, Ion Channel Regulation and Function, Gastrointestinal Motility and Disorders, Lipid Membrane Structure and Behavior, and Receptor Mechanisms and Signaling.

Chung Ming Tse has authored research papers published in various scientific journals. Recent publications include:

  • Fluid shear stress enhances differentiation of jejunal human enteroids in Intestine-Chip (2020), published in American Journal of Physiology-Gastrointestinal and Liver Physiology
  • Identification of Intestinal NaCl Absorptive-Anion Secretory Cells: Potential Functional Significance (2022), published in Frontiers in Physiology
  • SLC26A3 (DRA) is stimulated in a synergistic, intracellular Ca 2+ -dependent manner by cAMP and ATP in intestinal epithelial cells (2023), published in American Journal of Physiology-Cell Physiology
  • The Air-Liquid Interface Reorganizes Membrane Lipids and Enhances the Recruitment of Slc26a3 to Lipid-Rich Domains in Human Colonoid Monolayers (2023), published in International Journal of Molecular Sciences
  • Cholinergic-induced anion secretion in murine jejunal enteroids involves synergy between muscarinic and nicotinic pathways (2020), published in American Journal of Physiology-Cell Physiology

Their frequent coauthors have included Mark Donowitz, Rafiquel Sarker, Ruxian Lin, Varsha Singh, and George McNamara, indicating collaborative work in related research areas.

Common publication venues for Chung Ming Tse's work reflect their interdisciplinary focus and include Gastroenterology, American Journal of Physiology-Cell Physiology, Scientific Reports, American Journal of Physiology-Gastrointestinal and Liver Physiology, and Frontiers in Physiology.

Best Publications

  • cAMP-mediated inhibition of the epithelial brush border Na+/H+ exchanger, NHE3, requires an associated regulatory protein.

    C. H Chris Yun;Soohyuk Oh;Mirza Zizak;Deborah Steplock;Deborah Steplock

  • Kinetic and pharmacological properties of cloned human equilibrative nucleoside transporters, ENT1 and ENT2, stably expressed in nucleoside transporter-deficient PK15 cells. Ent2 exhibits a low affinity for guanosine and cytidine but a high affinity for inosine.

    Jeffrey L. Ward;Azeem Sherali;Zhi Ping Mo;Chung Ming Tse

  • Cloning and sequencing of a rabbit cDNA encoding an intestinal and kidney-specific Na+/H+ exchanger isoform (NHE-3).

    C M Tse;S R Brant;M S Walker;J Pouyssegur

  • NHE2 and NHE3 are human and rabbit intestinal brush-border proteins.

    W. A. Hoogerwerf;S. C. Tsao;O. Devuyst;S. A. Levine

  • Mammalian Na+/H+ exchanger gene family: structure and function studies

    C. H C Yun;Chung Ming Tse;S. K. Nath;S. A. Levine

  • SLC9/NHE gene family, a plasma membrane and organellar family of Na⁺/H⁺ exchangers

    Mark Donowitz;C. Ming Tse;Daniel Guido Fuster

  • Cloning and expression of a rabbit cDNA encoding a serum-activated ethylisopropylamiloride-resistant epithelial Na+/H+ exchanger isoform (NHE-2).

    Chung-Ming Tse;Susan A. Levine;C. H. Chris Yun;Marshall H. Montrose

  • Kinetics and regulation of three cloned mammalian Na+/H+ exchangers stably expressed in a fibroblast cell line.

    Susan A. Levine;Marshall H. Montrose;Chung Ming Tse;Mark Donowitz

  • NHERF family and NHE3 regulation

    Mark Donowitz;Boyoung Cha;Nicholas C. Zachos;Christopher L. Brett

  • Structure/function studies of mammalian Na-H exchangers--an update.

    C. H. Yun;Chung Ming Tse;S. Nath;S. L. Levine

  • Subcellular Redistribution Is Involved in Acute Regulation of the Brush Border Na+/H+ Exchanger Isoform 3 in Human Colon Adenocarcinoma Cell Line Caco-2 PROTEIN KINASE C-MEDIATED INHIBITION OF THE EXCHANGER

    Andrzej J. Janecki;Marshall H. Montrose;Piotr Zimniak;Alain Zweibaum

  • Molecular cloning and expression of a cDNA encoding the rabbit ileal villus cell basolateral membrane Na+/H+ exchanger.

    C. M. Tse;A. I. Ma;V. W. Yang;A. J.M. Watson

  • Cloning, tissue distribution, and functional analysis of the human Na+/N+ exchanger isoform, NHE3

    S. R. Brant;C. H. Chris Yun;M. Donowitz;C.-M. Tse

  • Polarized distribution of key membrane transport proteins in the rat submandibular gland

    Xinjun He;Chung Ming Tse;Mark Donowitz;Seth L. Alper

  • Squalamine, a novel cationic steroid, specifically inhibits the brush-border Na+/H+ exchanger isoform NHE3

    S. Akhter;S. K. Nath;C. M. Tse;J. Williams

  • Mitochondrial expression of the human equilibrative nucleoside transporter 1 (hENT1) results in enhanced mitochondrial toxicity of antiviral drugs

    Yurong Lai;Chung Ming Tse;Jashvant D. Unadkat

  • In situ hybridization and immunolocalization of concentrative and equilibrative nucleoside transporters in the human intestine, liver, kidneys, and placenta

    Rajgopal Govindarajan;Aimee H. Bakken;Kelly L. Hudkins;Yurong Lai;Yurong Lai

  • Functional characteristics of a cloned epithelial Na+/H+ exchanger (NHE3): Resistance to amiloride and inhibition by protein kinase C

    Chung Ming Tse;Susan A. Levine;C. H.Chris Yun;Steven R. Brant

  • Brush Border Phosphatidylinositol 3-Kinase Mediates Epidermal Growth Factor Stimulation of Intestinal NaCl Absorption and Na+/H+ Exchange (∗)

    Seema Khurana;Samir K. Nath;Susan A. Levine;Joellyn M. Bowser

  • Facilitated mitochondrial import of antiviral and anticancer nucleoside drugs by human equilibrative nucleoside transporter-3

    Rajgopal Govindarajan;George P.H. Leung;Mingyan Zhou;Chung Ming Tse

Frequent Co-Authors

Mark Donowitz
Mark Donowitz Johns Hopkins University School of Medicine
C. Chris Yun
C. Chris Yun Emory University
Edward J. Weinman
Edward J. Weinman University of Maryland, Baltimore
Jashvant D. Unadkat
Jashvant D. Unadkat University of Washington
Jerrold R. Turner
Jerrold R. Turner Brigham and Women's Hospital
Marçal Pastor-Anglada
Marçal Pastor-Anglada University of Barcelona
Simon Ming-Yuen Lee
Simon Ming-Yuen Lee University of Macau
Michel De Waard
Michel De Waard University of Nantes
Heini Murer
Heini Murer University of Zurich
Alan S. Verkman
Alan S. Verkman University of California, San Francisco

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