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Molecular Biology

D-Index
46
Citations
17126
World Ranking
2771
National Ranking
217

Overview

Beiyuan Fu is a researcher affiliated with the Wellcome Sanger Institute in the United Kingdom. Their work primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with additional contributions to Agricultural and Biological Sciences. Within these areas, their research focuses on several subfields including Molecular Biology, Plant Science, Genetics, Cancer Research, and Parasitology.

The research topics covered by Beiyuan Fu include:

  • Chromosomal and Genetic Variations
  • CRISPR and Genetic Engineering
  • Genomics and Phylogenetic Studies
  • Cancer Genomics and Diagnostics
  • DNA Repair Mechanisms
  • Parasites and Host Interactions
  • Epigenetics and DNA Methylation

Their recent publications demonstrate a breadth of interest in genetics and genomic technologies. These include:

  • "Combinatorial CRISPR screen identifies fitness effects of gene paralogues," 2021, Nature Communications
  • "Simultaneous sequencing of genetic and epigenetic bases in DNA," 2023, Nature Biotechnology
  • "Population Structure, Stratification, and Introgression of Human Structural Variation," 2020, Cell
  • "Assembled chromosomes of the blood fluke Schistosoma mansoni provide insight into the evolution of its ZW sex-determination system," 2021, bioRxiv (Cold Spring Harbor Laboratory)
  • "Genetic determinants of micronucleus formation in vivo," 2024, Nature

These works address topics ranging from CRISPR screening and genetic fitness effects to epigenetic sequencing and structural variation in human populations. The research on Schistosoma mansoni adds an aspect of parasitology relevant to host-parasite interactions and sex-determination mechanisms.

Frequent co-authors who have collaborated multiple times with Beiyuan Fu include:

  • Fengtang Yang
  • David J. Adams
  • Sarah K. Buddenborg
  • Alan Tracey
  • Duncan Berger

Beiyuan Fu's publications are commonly found in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Zenodo (CERN European Organization for Nuclear Research)
  • Nature Communications
  • Nature Biotechnology
  • Cell

Their work intersects multiple disciplines that merge genetics with molecular biology, cancer diagnostics, and the study of epigenetic processes, contributing to ongoing scientific discussions in these areas.

Best Publications

  • The zebrafish reference genome sequence and its relationship to the human genome.

    Kerstin Howe;Matthew D. Clark;Carlos F. Torroja;Carlos F. Torroja;James Torrance

  • Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development

    Philip J. Stephens;Chris D. Greenman;Beiyuan Fu;Fengtang Yang

  • Signatures of mutation and selection in the cancer genome

    Graham R. Bignell;Chris D. Greenman;Helen Davies;Adam P. Butler

  • Human blood vessel organoids as a model of diabetic vasculopathy

    Reiner A. Wimmer;Alexandra Leopoldi;Martin Aichinger;Nikolaus Wick

  • Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes

    Sebastian Mueller;Thomas Engleitner;Thomas Engleitner;Roman Maresch;Roman Maresch;Magdalena Zukowska

  • Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells.

    Harveer Dev;Harveer Dev;Ting-Wei Will Chiang;Chloe Lescale;Inge de Krijger

  • Genome Sequencing and Analysis of the Tasmanian Devil and Its Transmissible Cancer

    Elizabeth P. Murchison;Ole B. Schulz-Trieglaff;Zemin Ning;Ludmil B. Alexandrov

  • Establishment of porcine and human expanded potential stem cells

    Xuefei Gao;Xuefei Gao;Monika Nowak-Imialek;Monika Nowak-Imialek;Xi Chen;Dongsheng Chen

  • Establishment of mouse expanded potential stem cells

    Jian Yang;David J. Ryan;Wei Wang;Jason Cheuk-Ho Tsang

  • Transmissible Dog Cancer Genome Reveals the Origin and History of an Ancient Cell Lineage

    Elizabeth P. Murchison;Elizabeth P. Murchison;David C. Wedge;Ludmil B. Alexandrov;Beiyuan Fu

  • CRISPR/Cas9 somatic multiplex-mutagenesis for high-throughput functional cancer genomics in mice

    Julia Weber;Julia Weber;Rupert Öllinger;Mathias Friedrich;Ursula Ehmer

  • Sixteen diverse laboratory mouse reference genomes define strain-specific haplotypes and novel functional loci

    Jingtao Lilue;Jingtao Lilue;Anthony G Doran;Anthony G Doran;Ian T Fiddes;Monica Abrudan

  • Reciprocal chromosome painting among human, aardvark, and elephant (superorder Afrotheria) reveals the likely eutherian ancestral karyotype

    F. Yang;E. Z. Alkalaeva;P. L. Perelman;A. T. Pardini

  • Refined genome-wide comparative map of the domestic horse, donkey and human based on cross-species chromosome painting: insight into the occasional fertility of mules.

    Fengtang Yang;Beiyuan Fu;Patricia C. M. O'Brien;Wenhui Nie

  • Factor V Leiden and thermolabile methylenetetrahydrofolate reductase gene variants in an East Anglian preeclampsia cohort.

    Kevin M. O’Shaughnessy;Beiyuan Fu;Franco Ferraro;Ian Lewis

  • ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks

    Gabriel Balmus;Domenic Pilger;Julia Coates;Mukerrem Demir

  • Estimation of rearrangement phylogeny for cancer genomes

    Chris D. Greenman;Chris D. Greenman;Erin D. Pleasance;Scott Newman;Fengtang Yang

  • Obesity, starch digestion and amylase: association between copy number variants at human salivary (AMY1) and pancreatic (AMY2) amylase genes

    Danielle Carpenter;Sugandha Dhar;Laura M. Mitchell;Beiyuan Fu

  • Cross-species chromosome painting

    Malcolm A. Ferguson-Smith;Stefan Muller;Johannes Friederich Wienberg

  • Cross-species chromosome painting among camel, cattle, pig and human: further insights into the putative Cetartiodactyla ancestral karyotype

    Gabriel Balmus;Vladimir A. Trifonov;Vladimir A. Trifonov;Larisa S. Biltueva;Patricia C.M. O’Brien

Frequent Co-Authors

Fengtang Yang
Fengtang Yang Wellcome Sanger Institute
Malcolm A. Ferguson-Smith
Malcolm A. Ferguson-Smith University of Cambridge
Patricia C. M. O’Brien
Patricia C. M. O’Brien University of Cambridge
Pentao Liu
Pentao Liu University of Hong Kong
Alexander S. Graphodatsky
Alexander S. Graphodatsky Novosibirsk State University
David J. Adams
David J. Adams Wellcome Sanger Institute
Carol Churcher
Carol Churcher University of Cambridge
Peter J. Campbell
Peter J. Campbell Wellcome Sanger Institute
Terence J. Robinson
Terence J. Robinson Stellenbosch University
Michael R. Stratton
Michael R. Stratton Wellcome Sanger Institute

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