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Andrew C. Issekutz

Andrew C. Issekutz

D-Index & Metrics

Immunology

D-Index
72
Citations
16884
World Ranking
2237
National Ranking
48

Overview

Andrew C. Issekutz is affiliated with Dalhousie University in Canada and conducts research primarily in immunology and microbiology as well as medicine. Their work focuses on understanding immune cell function and interaction, with particular attention to autoimmune and inflammatory disorders, T-cell and B-cell immunology, and immunodeficiency conditions. They also engage in research related to Kawasaki disease and coronary complications.

Their recent publications include studies on immune system modulation and clinical case reports. Notable papers are:

  • High Dose Intravenous IgG Therapy Modulates Multiple NK Cell and T Cell Functions in Patients With Immune Dysregulation (2021, Frontiers in Immunology)
  • IPEX Syndrome with Normal FOXP3 Protein Expression in Treg Cells in an Infant Presenting with Intractable Diarrhea as a Single Symptom (2020, Case Reports in Immunology)

These publications highlight research on immune dysregulation therapies and rare immunological syndromes with clinical symptoms. The venues for publishing include Frontiers in Immunology and Case Reports in Immunology, among others.

Collaborations have been a part of Issekutz's research, with frequent coauthors including:

  • Thomas B. Issekutz
  • Beáta Dérfalvi
  • Sarah M. McAlpine
  • Sarah E. Roberts
  • John Heath

Their work spans multiple subfields encompassing immunology, surgery, and hematology. This interdisciplinary approach supports the study of immune cell interactions and related pathological conditions.

Best Publications

  • Activated STING in a Vascular and Pulmonary Syndrome

    Y. Liu;A.A. Jesus;B. Marrero;D. Yang

  • Pyogenic Bacterial Infections in Humans with MyD88 Deficiency

    Horst Von Bernuth;Capucine Picard;Capucine Picard;Zhongbo Jin;Rungnapa Pankla;Rungnapa Pankla

  • Clinical Features and Outcome of Patients With IRAK-4 and MyD88 Deficiency

    Capucine Picard;Capucine Picard;Horst Von Bernuth;Horst Von Bernuth;Horst Von Bernuth;Pegah Ghandil;Pegah Ghandil;Pegah Ghandil;Maya Chrabieh;Maya Chrabieh

  • Selective predisposition to bacterial infections in IRAK-4–deficient children: IRAK-4–dependent TLRs are otherwise redundant in protective immunity

    Cheng Lung Ku;Horst Von Bernuth;Horst Von Bernuth;Capucine Picard;Shen Ying Zhang

  • The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88

    Bing He;Raul Santamaria;Weifeng Xu;Montserrat Cols

  • Molecular Mechanisms Involved in Lymphocyte Recruitment in Inflamed Brain Microvessels: Critical Roles for P-Selectin Glycoprotein Ligand-1 and Heterotrimeric Gi-Linked Receptors

    Laura Piccio;Barbara Rossi;Elio Scarpini;Carlo Laudanna

  • Activation of endothelial cells via antibody-enhanced dengue virus infection of peripheral blood monocytes.

    R Anderson;S Wang;C Osiowy;A C Issekutz

  • Primary immunodeficiency diseases: Genomic approaches delineate heterogeneous Mendelian disorders.

    Asbjørg Stray-Pedersen;Hanne Sørmo Sorte;Pubudu Samarakoon;Tomasz Gambin;Tomasz Gambin

  • Removal of gram-negative endotoxin from solutions by affinity chromatography

    Andrew C. Issekutz

  • Hereditary angiodema: a current state-of-the-art review, VII: Canadian Hungarian 2007 International Consensus Algorithm for the Diagnosis, Therapy, and Management of Hereditary Angioedema

    Tom Bowen;Marco Cicardi;Konrad Bork;Bruce Zuraw

  • Heme oxygenase modulates selectin expression in different regional vascular beds.

    T J Vachharajani;J Work;A C Issekutz;D N Granger

  • Direct evidence of leukocyte adhesion in arterioles by angiotensin II

    Ángeles Álvarez;Miguel Cerdá-Nicolás;Yafa Naim Abu Nabah;Manuel Mata

  • Basic fibroblast growth factor (bFGF, FGF-2) potentiates leukocyte recruitment to inflammation by enhancing endothelial adhesion molecule expression.

    Sandra I. Zittermann;Andrew C. Issekutz

  • Connexin 43 mediates spread of Ca2+ -dependent proinflammatory responses in lung capillaries

    Kaushik Parthasarathi;Hideo Ichimura;Eiji Monma;Jens Lindert

  • Angiotensin II induces leukocyte-endothelial cell interactions in vivo via AT(1) and AT(2) receptor-mediated P-selectin upregulation.

    Laura Piqueras;Paul Kubes;Angeles Alvarez;Enrique O’Connor

  • Quantitation of eosinophil and neutrophil infiltration into rat lung by specific assays for eosinophil peroxidase and myeloperoxidase. Application in a Brown Norway rat model of allergic pulmonary inflammation

    Thorsten Schneider;Andrew C. Issekutz

  • Role of ICAM-1 and ICAM-2 and alternate CD11/CD18 ligands in neutrophil transendothelial migration.

    A C Issekutz;D Rowter;T A Springer

  • Targeting VEGF-encapsulated immunoliposomes to MI heart improves vascularity and cardiac function

    Robert C. Scott;Jenna M. Rosano;Zhanna Ivanov;Bin Wang

  • Menopause and Ovariectomy Cause a Low Grade of Systemic Inflammation That May Be Prevented by Chronic Treatment with Low Doses of Estrogen or Losartan

    May Abu-Taha;Cristina Rius;Carlos Hermenegildo;Inmaculada Noguera

  • Mechano-oxidative coupling by mitochondria induces proinflammatory responses in lung venular capillaries

    Hideo Ichimura;Kaushik Parthasarathi;Sadiqa Quadri;Andrew C. Issekutz

Frequent Co-Authors

Thomas B. Issekutz
Thomas B. Issekutz Dalhousie University
Jahar Bhattacharya
Jahar Bhattacharya Columbia University
Jean-Laurent Casanova
Jean-Laurent Casanova The University of Texas Southwestern Medical Center
Horst von Bernuth
Horst von Bernuth Charité - University Medicine Berlin
Capucine Picard
Capucine Picard Université Paris Cité
Michael J. Hickey
Michael J. Hickey Monash Medical Centre
Laurent Abel
Laurent Abel Université Paris Cité
László Maródi
László Maródi Rockefeller University
Shen-Ying Zhang
Shen-Ying Zhang Rockefeller University

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Related Online Degrees & Career Pathways

Studying Immunology in the USA opens doors to various allied health and nursing careers. Many students consider supplementing their knowledge with specialized nursing programs to expand their career options. For individuals without a nursing background, there are accessible options such as online nursing programs for non nurses that offer a streamlined transition into the healthcare field.

For those seeking rapid entry into nursing, 12-month accelerated nursing programs provide an efficient pathway to earn a Bachelor of Science in Nursing (BSN), allowing students to quickly advance their clinical expertise.

Entry-level nursing careers can also be explored through easy admission LPN programs. These Licensed Practical Nurse programs offer a practical and accessible way to begin working in healthcare settings while applying foundational immunology knowledge.

For advanced practice roles, many professionals pursue easiest online nurse practitioner programs. These programs prepare graduates to deliver high-level patient care, often integrating immunology principles into their practice to better understand disease mechanisms and immune responses.

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