World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
44
Citations
13569
World Ranking
4743
National Ranking
2134

Overview

Allan J. Zajac is affiliated with the University of Alabama at Birmingham in the United States. Their research primarily spans the fields of immunology and microbiology, with additional work in medicine. Subfields include immunology, oncology, epidemiology, infectious diseases, and genetics.

Their research topics encompass:

  • Immune cell function and interaction
  • T-cell and B-cell immunology
  • Immunotherapy and immune responses
  • CAR-T cell therapy research
  • Cytomegalovirus and herpesvirus research
  • Blood disorders and treatments
  • Viral infections and immunology research

Zajac has contributed to a number of publications, with a frequent presence in venues such as The Journal of Immunology, UNC Libraries, Immunity, Science Advances, and Science Immunology. Their most recent papers include:

  • "Gfi1 controls the formation of effector-like CD8+ T cells during chronic infection and cancer," 2025, Nature Communications
  • "Tfh-cell-derived interleukin 21 sustains effector CD8+ T cell responses during chronic viral infection," 2022, Immunity
  • "Intrinsic IL-2 production by effector CD8 T cells affects IL-2 signaling and promotes fate decisions, stemness, and protection," 2022, Science Immunology
  • "IL-10-producing Tfh cells accumulate with age and link inflammation with age-related immune suppression," 2020, Science Advances
  • "Editorial overview: Viral immunology before COVID-19," 2021, Current Opinion in Virology

Frequent coauthors in Zajac's work include Jennifer T Ingram, Laurie E. Harrington, Shannon M. Kahan, Casey T. Weaver, and Robert S. Welner.

Best Publications

  • Viral Immune Evasion Due to Persistence of Activated T Cells Without Effector Function

    Allan J. Zajac;Joseph N. Blattman;Kaja Murali-Krishna;David J.D. Sourdive

  • Counting Antigen-Specific CD8 T Cells: A Reevaluation of Bystander Activation during Viral Infection

    Kaja Murali-Krishna;John D Altman;M Suresh;David J.D Sourdive

  • T-cell exhaustion: characteristics, causes and conversion

    John S. Yi;Maureen A. Cox;Allan J. Zajac

  • A Vital Role for Interleukin-21 in the Control of a Chronic Viral Infection

    John S. Yi;Ming Du;Allan J. Zajac

  • CD4+ T cell help is required for the formation of a cytolytic CD8+ T cell subset that protects against chronic infection and cancer

    Ryan Zander;David Schauder;Gang Xin;Christine Nguyen

  • Cutting Edge: Increased Expression of Bcl-2 in Antigen-Specific Memory CD8+ T Cells

    Jason M. Grayson;Allan J. Zajac;John D. Altman;Rafi Ahmed

  • T cell exhaustion during persistent viral infections.

    Shannon M. Kahan;E. John Wherry;Allan J. Zajac

  • Ablation of CD8 and CD4 T Cell Responses by High Viral Loads

    Michael J. Fuller;Allan J. Zajac

  • Memory CD4 T cells emerge from effector T-cell progenitors.

    Laurie E. Harrington;Karen M. Janowski;James R. Oliver;Allan J. Zajac

  • Maintenance, Loss, and Resurgence of T Cell Responses During Acute, Protracted, and Chronic Viral Infections

    Michael J. Fuller;Aaruni Khanolkar;Anne E. Tebo;Allan J. Zajac

  • Conserved T Cell Receptor Repertoire in Primary and Memory CD8 T Cell Responses to an Acute Viral Infection

    David J.D. Sourdive;Kaja Murali-Krishna;John D. Altman;Allan J. Zajac

  • Dynamic regulation of T follicular regulatory cell responses by interleukin 2 during influenza infection

    Davide Botta;Michael J Fuller;Tatiana T Marquez-Lago;Holly Bachus

  • In vitro characterization of an internal ribosomal entry site (IRES) present within the 5' nontranslated region of hepatitis A virus RNA: comparison with the IRES of encephalomyocarditis virus.

    Edwin A. Brown;Allan J. Zajac;Stanley M. Lemon

  • Viral and bacterial infections induce expression of multiple NK cell receptors in responding CD8(+) T cells.

    Christopher W. McMahon;Allan J. Zajac;Amanda M. Jamieson;Laura Corral

  • CD4 T Cell-Dependent CD8 T Cell Maturation

    Aaruni Khanolkar;Michael J. Fuller;Allan J. Zajac

  • Attenuated Mutants of Venezuelan Equine Encephalitis Virus Containing Lethal Mutations in the PE2 Cleavage Signal Combined with a Second-Site Suppressor Mutation in E1

    Nancy L. Davis;Kevin W. Brown;Gary F. Greenwald;Allan J. Zajac

  • Tfh-cell-derived interleukin 21 sustains effector CD8+ T cell responses during chronic viral infection.

    Unknown

  • Anti-viral CD8 T cells and the cytokines that they love

    Maureen A. Cox;Shannon M. Kahan;Allan J. Zajac

  • Codon usage optimization of HIV type 1 subtype C gag, pol, env, and nef genes: In vitro expression and immune responses in DNA-vaccinated mice

    Feng Gao;Yingying Li;Julie M. Decker;Fred W. Peyerl

  • Cutting Edge: Emergence of CD127high Functionally Competent Memory T Cells Is Compromised by High Viral Loads and Inadequate T Cell Help

    Michael J. Fuller;David A. Hildeman;Steffanie Sabbaj;Dalia E. Gaddis

  • Bim mediates apoptosis of CD127lo effector T cells and limits T cell memory

    Sara Wojciechowski;Michael B. Jordan;Yanan Zhu;Janice White

Frequent Co-Authors

John D. Mountz
John D. Mountz University of Alabama at Birmingham
Rafi Ahmed
Rafi Ahmed Emory University
David T. Curiel
David T. Curiel Washington University in St. Louis
Casey T. Weaver
Casey T. Weaver University of Alabama at Birmingham
John D. Altman
John D. Altman Emory University
David A. Hildeman
David A. Hildeman Cincinnati Children's Hospital Medical Center
Jeffrey A. Frelinger
Jeffrey A. Frelinger University of Arizona
Harinder Singh
Harinder Singh University of Pittsburgh
Paul A. Goepfert
Paul A. Goepfert University of Alabama at Birmingham
Kohtaro Fujihashi
Kohtaro Fujihashi University of Alabama at Birmingham

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For those interested in Immunology, exploring related degrees in nursing and healthcare can open numerous career opportunities. Many students pursue online programs that offer flexibility and accelerated paths to advance their qualifications. For instance, accelerated FNP programs allow registered nurses to quickly become family nurse practitioners, expanding their scope to provide more specialized care in various clinical settings.

Transitioning from a family nurse practitioner to a more specialized role, such as an acute care nurse practitioner, is another viable pathway. Resources like acute care nurse practitioner programs guide professionals through the educational and certification processes required for this shift, which is essential for those looking to work in hospital or critical care environments.

Additionally, non-nurses interested in entering the healthcare field can explore online ABSN programs for non nurses, which provide a fast-tracked Bachelor of Science in Nursing and essential training to join the workforce efficiently.

Financial considerations are important when choosing a career path. Understanding how much do DNPs make can help prospective students evaluate the return on investment for advanced degrees like the Doctor of Nursing Practice, offering competitive salaries across the United States.

Best Scientists Citing Allan J. Zajac

Trending Scientists

Recently Published Articles