Alan J. Korman spends much of his time researching Immunology, Immunotherapy, Antigen, Immune system and Blockade. His work deals with themes such as Cytotoxic T cell and Cancer research, which intersect with Immunology. His Immunotherapy study integrates concerns from other disciplines, such as Monoclonal antibody and Oncology.
Alan J. Korman combines subjects such as Cancer and Primary and secondary antibodies with his study of Monoclonal antibody. His Oncology study deals with Avelumab intersecting with Breast cancer, Ovarian cancer, Pancreatic cancer and Atezolizumab. His Ipilimumab research is multidisciplinary, incorporating perspectives in Nivolumab and Clinical trial.
His main research concerns Antibody, Immunology, Cancer research, Monoclonal antibody and Cancer. Alan J. Korman usually deals with Antibody and limits it to topics linked to Molecular biology and Ligand and Cell. His work focuses on many connections between Immunology and other disciplines, such as Cytotoxic T cell, that overlap with his field of interest in CD8.
His research integrates issues of Immune checkpoint, Receptor, Blockade and Immunotherapy in his study of Cancer research. His Monoclonal antibody research integrates issues from Programmed death, Programmed death 1, Virology, PD-L1 and Primary and secondary antibodies. His work investigates the relationship between Ipilimumab and topics such as Nivolumab that intersect with problems in Lung cancer.
Alan J. Korman mainly focuses on Antibody, Cancer research, Cancer, Immune system and Immunotherapy. His work carried out in the field of Antibody brings together such families of science as Molecular biology, Anti pd 1 and Biochemistry, Nucleic acid. He interconnects Immune checkpoint and Cytotoxic T cell, CD8, TIGIT in the investigation of issues within Cancer research.
His studies in Cancer integrate themes in fields like Combination therapy and Sarcoma. His biological study spans a wide range of topics, including Glioma, Receptor and Antigen. His biological study deals with issues like T cell, which deal with fields such as Radiation therapy, Galectin-1, Downregulation and upregulation and Histidine.
His scientific interests lie mostly in Cancer research, CD8, Cytotoxic T cell, Immune system and Immunotherapy. His work in Cancer research addresses issues such as Immune checkpoint, which are connected to fields such as Prostate cancer, Myeloid, Cancer cell, Castration Resistance and Tumor progression. His CD8 research incorporates elements of Blockade and Melanoma.
His research in Cytotoxic T cell tackles topics such as Antibody which are related to areas like Histidine, Cell biology, Glycoprotein and Brain tumor. Immunotherapy is a primary field of his research addressed under Cancer. The concepts of his Cancer study are interwoven with issues in Regulatory T cell and Sarcoma.
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Safety, activity, and immune correlates of anti-PD-1 antibody in cancer.
Suzanne L. Topalian;F. Stephen Hodi;Julie R. Brahmer;Scott N. Gettinger.
The New England Journal of Medicine (2012)
Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer
Julie R. Brahmer;Scott S. Tykodi;Scott S. Tykodi;Laura Q.M. Chow;Wen Jen Hwu.
The New England Journal of Medicine (2012)
Nivolumab plus Ipilimumab in Advanced Melanoma
Jedd D. Wolchok;Harriet Kluger;Margaret K. Callahan;Michael A. Postow.
The New England Journal of Medicine (2013)
Phase I Study of Single-Agent Anti–Programmed Death-1 (MDX-1106) in Refractory Solid Tumors: Safety, Clinical Activity, Pharmacodynamics, and Immunologic Correlates
Julie R. Brahmer;Charles G. Drake;Ira Wollner;John D. Powderly.
Journal of Clinical Oncology (2010)
Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens
Matthew M. Gubin;Xiuli Zhang;Heiko Schuster;Etienne Caron.
Nature (2014)
Immune Inhibitory Molecules LAG-3 and PD-1 Synergistically Regulate T-cell Function to Promote Tumoral Immune Escape
Seng Ryong Woo;Meghan E Turnis;Monica V Goldberg;Jaishree Bankoti.
Cancer Research (2012)
Human monoclonal antibodies to programmed death ligand 1 (pd-l1)
Korman Alan J;Selby Mark J;Wang Changyu;Srinivasan Mohan.
(2006)
Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients
F. Stephen Hodi;Martin C. Mihm;Robert J. Soiffer;Frank G. Haluska.
Proceedings of the National Academy of Sciences of the United States of America (2003)
Anti-CTLA-4 antibodies of IgG2a isotype enhance antitumor activity through reduction of intratumoral regulatory T cells.
Mark J. Selby;John J. Engelhardt;Michael Quigley;Karla A. Henning.
Cancer immunology research (2013)
Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti–CTLA-4 antibodies
Karl S. Peggs;Sergio A. Quezada;Cynthia A. Chambers;Alan J. Korman.
Journal of Experimental Medicine (2009)
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