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Medicine

D-Index
154
Citations
151729
World Ranking
981
National Ranking
563

Research.com Recognitions

  • 1995 - Kelly West Award, American Diabetes Association

Overview

William C. Knowler is affiliated with the National Institutes of Health in the United States. Their research primarily spans the fields of medicine and biochemistry, genetics, and molecular biology, with a substantial focus on endocrinology, diabetes, and metabolism. Their work also extends into genetics, physiology, molecular biology, and epidemiology as notable subfields of study.

Their scientific output covers a range of main topics that include diabetes treatment and management, the intersection of diabetes with cardiovascular risks and lipoproteins, metabolism in relation to diabetes and cancer, diabetes management and research, genetic associations and epidemiology, diet and metabolism studies, and connections between obesity, physical activity, and diet.

William C. Knowler has contributed to numerous journals, with frequent publications appearing in:

  • Diabetes
  • Diabetes Care
  • Obesity
  • The Journal of Clinical Endocrinology & Metabolism
  • Diabetologia

Their recent papers include the following:

  • Intratrial Exposure to Vitamin D and New-Onset Diabetes Among Adults With Prediabetes: A Secondary Analysis From the Vitamin D and Type 2 Diabetes (D2d) Study, 2020, published in Diabetes Care
  • Effects of Long-term Metformin and Lifestyle Interventions on Cardiovascular Events in the Diabetes Prevention Program and Its Outcome Study, 2022, published in Circulation
  • Albuminuria Testing in Hypertension and Diabetes: An Individual-Participant Data Meta-Analysis in a Global Consortium, 2021, published in Hypertension
  • COVID-19 in People With Diabetes: Urgently Needed Lessons From Early Reports, 2020, published in Diabetes Care
  • Effect of Metformin and Lifestyle Interventions on Mortality in the Diabetes Prevention Program and Diabetes Prevention Program Outcomes Study, 2021, published in Diabetes Care

Known frequent co-authors include:

  • Robert L. Hanson
  • Dana Dabelea
  • Steven E. Kahn
  • Karen Johnson
  • Helen P. Hazuda

William C. Knowler received the Kelly West Award from the American Diabetes Association in 1995.

Best Publications

  • Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin

    W. C. Knowler;E. Barrett-connor;S. E. Fowler;R. F. Hamman

  • Report of the expert committee on the diagnosis and classification of diabetes mellitus

    James R. Gavin;K. G M M Alberti;Mayer B. Davidson;Ralph A. DeFronzo

  • Follow-up report on the diagnosis of diabetes mellitus.

    Saul Genuth;K. G M M Alberti;Peter Bennett;John Buse

  • 10-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study.

    William C Knowler;Sarah E Fowler;Richard F Hamman

  • International Expert Committee Report on the Role of the A1C Assay in the Diagnosis of Diabetes

    David M. Nathan;Beverly Balkau;Enzo Bonora;Knut Borch-Johnsen

  • Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes

    R. R. Wing;P. Bolin;F. L. Brancati;G. A. Bray

  • Insulin Resistance and Insulin Secretory Dysfunction as Precursors of Non-Insulin-Dependent Diabetes Mellitus: Prospective Studies of Pima Indians

    Stephen Lillioja;David M. Mott;Maximilian Spraul;Robert Ferraro

  • Benefits of Modest Weight Loss in Improving Cardiovascular Risk Factors in Overweight and Obese Individuals With Type 2 Diabetes

    Rena R. Wing;Wei Lang;Thomas A. Wadden;Monika Safford

  • Childhood obesity, other cardiovascular risk factors, and premature death.

    Paul W. Franks;Robert L. Hanson;William C. Knowler;Maurice L. Sievers

  • Adiponectin and development of type 2 diabetes in the Pima Indian population

    Robert S Lindsay;Tohru Funahashi;Robert L Hanson;Yuji Matsuzawa

  • Prevalence of Diabetes and Impaired Glucose Tolerance and Plasma Glucose Levels in U.S. Population Aged 20–74 Yr

    Maureen I Harris;Wilbur C Hadden;William C Knowler;Peter H Bennett

  • Reduced Rate of Energy Expenditure as a Risk Factor for Body-Weight Gain

    Eric Ravussin;Stephen Lillioja;William C. Knowler;Laurent Christin

  • Intrauterine exposure to diabetes conveys risks for type 2 diabetes and obesity: a study of discordant sibships.

    Dana Dabelea;Robert L. Hanson;Robert S. Lindsay;David J. Pettitt

  • Reduction in Weight and Cardiovascular Disease Risk Factors in Individuals With Type 2 Diabetes: One-Year Results of the Look AHEAD Trial

    Mark Espeland;Xavier Pi-Sunyer;George Blackburn;Frederick L. Brancati

  • Lower estimated glomerular filtration rate and higher albuminuria are associated with all-cause and cardiovascular mortality.: A collaborative meta-analysis of high-risk population cohorts

    Marije van der Velde;Kunihiro Matsushita;Josef Coresh;Brad C. Astor

  • TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program.

    Jose C. Florez;Kathleen A. Jablonski;Nick Bayley;Toni I. Pollin

  • Look AHEAD (Action for Health in Diabetes): design and methods for a clinical trial of weight loss for the prevention of cardiovascular disease in type 2 diabetes.

    Donna H Ryan;Mark A Espeland;Gary D Foster;Steven M Haffner

  • Long-term Effects of Lifestyle Intervention or Metformin on Diabetes Development and Microvascular Complications: the DPP Outcomes Study

    D. M. Nathan;E. Barrett-Connor;J.P. Crandall

  • Severe Periodontitis and Risk for Poor Glycemic Control in Patients with Non-Insulin-Dependent Diabetes Mellitus

    George W. Taylor;Brian A. Burt;Mark P. Becker;Robert J. Genco

  • Low ratio of fat to carbohydrate oxidation as predictor of weight gain: study of 24-h RQ

    F. Zurlo;S. Lillioja;A. Esposito del Puente;B. L. Nyomba

Frequent Co-Authors

Robert L. Hanson
Robert L. Hanson National Institutes of Health
Peter H. Bennett
Peter H. Bennett National Institutes of Health
Robert G. Nelson
Robert G. Nelson National Institutes of Health
David J. Pettitt
David J. Pettitt Kaiser Permanente
Clifton Bogardus
Clifton Bogardus National Institutes of Health
Steven E. Kahn
Steven E. Kahn University of Washington
Edward S. Horton
Edward S. Horton Harvard Medical School
David M. Nathan
David M. Nathan Harvard University
Rena R. Wing
Rena R. Wing Brown University
Karen C. Johnson
Karen C. Johnson University of Tennessee Health Science Center

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