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Microbiology

D-Index
72
Citations
23317
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1723
National Ranking
145

Overview

Trevor D. Lawley is a researcher affiliated with the Wellcome Sanger Institute in the United Kingdom. Their work primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with significant contributions to Medicine. Within these broad areas, they have a focus on Molecular Biology, Oncology, Infectious Diseases, Immunology, and Food Science.

The scientist's research frequently explores topics related to gut microbiota and health, including studies on Clostridium difficile and Clostridium perfringens. Other important topics include probiotics and fermented foods, cancer immunotherapy and biomarkers, cancer research and treatments, Escherichia coli research studies, and cancer genomics and diagnostics.

Trevor D. Lawley has contributed extensively to the scientific literature, with a significant number of publications appearing in notable venues. Frequent publication platforms include bioRxiv (Cold Spring Harbor Laboratory), Nature, Nature Reviews Microbiology, Cell, and Nature Communications.

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature
  • Nature Reviews Microbiology
  • Cell
  • Nature Communications

Some recent impactful papers authored or co-authored by Trevor D. Lawley include:

  • Massive expansion of human gut bacteriophage diversity, 2021, Cell
  • Identification of bacteria-derived HLA-bound peptides in melanoma, 2021, Nature
  • Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies, 2023, Nature
  • Distinct microbial and immune niches of the human colon, 2020, Nature Immunology
  • Gut-educated IgA plasma cells defend the meningeal venous sinuses, 2020, Nature

Collaboration is an important aspect of their work. Frequent co-authors include Kévin Vervier, Nitin Kumar, Yan Shao, Hilary P. Browne, and Mark Stares, with repeated joint contributions indicating ongoing scientific partnerships.

  • Kévin Vervier
  • Nitin Kumar
  • Yan Shao
  • Hilary P. Browne
  • Mark Stares

Best Publications

  • A new genomic blueprint of the human gut microbiota

    Alexandre Almeida;Alex L. Mitchell;Miguel Boland;Samuel C. Forster

  • Culturing of ‘unculturable’ human microbiota reveals novel taxa and extensive sporulation

    Hilary P. Browne;Samuel C. Forster;Samuel C. Forster;Samuel C. Forster;Blessing O. Anonye;Nitin Kumar

  • Stunted microbiota and opportunistic pathogen colonization in caesarean-section birth

    Yan Shao;Samuel C. Forster;Samuel C. Forster;Samuel C. Forster;Evdokia Tsaliki;Kevin Vervier

  • Emergence and global spread of epidemic healthcare-associated Clostridium difficile.

    Miao He;Fabio Miyajima;Paul Roberts;Louise Ellison

  • Bacteriophage targeting of gut bacterium attenuates alcoholic liver disease

    Yi Duan;Yi Duan;Cristina Llorente;Cristina Llorente;Sonja Lang;Katharina Brandl

  • Intestinal colonization resistance

    Trevor D Lawley;Alan W Walker

  • Targeted Restoration of the Intestinal Microbiota with a Simple, Defined Bacteriotherapy Resolves Relapsing Clostridium difficile Disease in Mice

    Trevor D. Lawley;Simon Clare;Alan W. Walker;Mark D. Stares

  • Massive expansion of human gut bacteriophage diversity

    Luis F. Camarillo-Guerrero;Alexandre Almeida;Guillermo Rangel-Pineros;Robert D. Finn

  • A human gut bacterial genome and culture collection for improved metagenomic analyses.

    Samuel C. Forster;Samuel C. Forster;Samuel C. Forster;Nitin Kumar;Blessing O. Anonye;Blessing O. Anonye;Alexandre Almeida;Alexandre Almeida

  • Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium

    Richard A. Stabler;Miao-Xia He;Lisa Dawson;Melissa Martin

  • F factor conjugation is a true type IV secretion system.

    T.D Lawley;W.A Klimke;M.J Gubbins;L.S Frost

  • Genome-wide screen for Salmonella genes required for long-term systemic infection of the mouse.

    Trevor D Lawley;Kaman Chan;Lucinda J Thompson;Charles C Kim

  • Evolutionary dynamics of Clostridium difficile over short and long time scales

    Miao He;Mohammed Sebaihia;Trevor D. Lawley;Richard A. Stabler

  • Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies

    Unknown

  • The Clostridium difficile spo0A Gene Is a Persistence and Transmission Factor

    Laura J. Deakin;Simon Clare;Robert P. Fagan;Lisa F. Dawson

  • Antibiotic treatment of Clostridium difficile carrier mice triggers a supershedder state, spore-mediated transmission, and severe disease in immunocompromised hosts.

    Trevor D. Lawley;Simon Clare;Alan W. Walker;David Goulding

  • Identification of bacteria-derived HLA-bound peptides in melanoma

    Shelly Kalaora;Adi Nagler;Deborah Nejman;Michal Alon

  • Dietary trehalose enhances virulence of epidemic Clostridium difficile

    J. Collins;C. Robinson;H. Danhof;C. W. Knetsch

  • Host Transmission of Salmonella enterica Serovar Typhimurium Is Controlled by Virulence Factors and Indigenous Intestinal Microbiota

    Trevor D. Lawley;Donna M. Bouley;Yana E. Hoy;Christine Gerke

  • DNA Methylation and Transcription Patterns in Intestinal Epithelial Cells From Pediatric Patients With Inflammatory Bowel Diseases Differentiate Disease Subtypes and Associate With Outcome

    Kate Joanne Howell;Kate Joanne Howell;Judith Kraiczy;Komal M. Nayak;Marco Gasparetto

  • Distinct Commensals Induce Interleukin-1β via NLRP3 Inflammasome in Inflammatory Monocytes to Promote Intestinal Inflammation in Response to Injury

    Sang Uk Seo;Nobuhiko Kamada;Raúl Muñoz-Planillo;Yun Gi Kim

  • Epithelial IL-22RA1-Mediated Fucosylation Promotes Intestinal Colonization Resistance to an Opportunistic Pathogen

    Tu Anh N. Pham;Simon Clare;David Goulding;Julia M. Arasteh

  • Proteomic and Genomic Characterization of Highly Infectious Clostridium difficile 630 Spores

    Trevor D. Lawley;Nicholas J. Croucher;Lu Yu;Simon Clare

Frequent Co-Authors

Gordon Dougan
Gordon Dougan University of Cambridge
Simon Clare
Simon Clare Wellcome Sanger Institute
Brendan W. Wren
Brendan W. Wren London School of Hygiene & Tropical Medicine
Diane E. Taylor
Diane E. Taylor University of Alberta
Ed J. Kuijper
Ed J. Kuijper Leiden University Medical Center
David Goulding
David Goulding Wellcome Sanger Institute
Julian Parkhill
Julian Parkhill University of Cambridge
Dale N. Gerding
Dale N. Gerding Veterans Health Administration
Thomas V. Riley
Thomas V. Riley Edith Cowan University
Sarah A. Teichmann
Sarah A. Teichmann University of Cambridge

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