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D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
13936
World Ranking
10788
National Ranking
827

Overview

David Goulding is affiliated with the Wellcome Sanger Institute in the United Kingdom. Their research spans multiple disciplines, primarily focusing on biochemistry, genetics, molecular biology, medicine, and agricultural and biological sciences.

The scientist's work addresses a range of specialized topics, including:

  • Infant Nutrition and Health
  • Proteins in Food Systems
  • Protein Hydrolysis and Bioactive Peptides
  • Gut Microbiota and Health
  • Digestive System and Related Health
  • Milk Quality and Mastitis in Dairy Cows
  • Probiotics and Fermented Foods

David Goulding has contributed to prominent research articles across well-recognized venues. Some of their recent papers include:

  • "An invariant Trypanosoma vivax vaccine antigen induces protective immunity" (2021, Nature)
  • "Host adaptation in gut Firmicutes is associated with sporulation loss and altered transmission cycle" (2021, Genome Biology)
  • "Control of oviductal fluid flow by the G-protein coupled receptor Adgrd1 is essential for murine embryo transit" (2021, Nature Communications)
  • "Influence of thermal processing on the physicochemical properties of bovine lactoferrin" (2021, International Dairy Journal)
  • "Defining the early stages of intestinal colonisation by whipworms" (2022, Nature Communications)

Their frequent publication venues further reflect the interdisciplinary nature of their work and include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • International Dairy Journal
  • SSRN Electronic Journal
  • Nature Communications
  • Food Chemistry

Collaboration is an integral part of Goulding's research output. Notable frequent co-authors are:

  • Jonathan O'Regan
  • James A. O'Mahony
  • Alan L. Kelly
  • Niamh Gowen
  • Maria A. Duque-Correa

In addition to their focus on molecular biology and biochemistry, Goulding's work often intersects with nutrition, food science, and epidemiology, reflecting a comprehensive approach to studying proteins, microbiota, and related health aspects.

Best Publications

  • Culturing of ‘unculturable’ human microbiota reveals novel taxa and extensive sporulation

    Hilary P. Browne;Samuel C. Forster;Samuel C. Forster;Samuel C. Forster;Blessing O. Anonye;Nitin Kumar

  • IFITM3 restricts the morbidity and mortality associated with influenza

    Aaron R. Everitt;Simon Clare;Thomas Charles Pertel;Sinu P. John

  • Juno is the egg Izumo receptor and is essential for mammalian fertilization

    Enrica Bianchi;Brendan Doe;David Goulding;Gavin J. Wright

  • Targeted Restoration of the Intestinal Microbiota with a Simple, Defined Bacteriotherapy Resolves Relapsing Clostridium difficile Disease in Mice

    Trevor D. Lawley;Simon Clare;Alan W. Walker;Mark D. Stares

  • Antibiotic treatment of Clostridium difficile carrier mice triggers a supershedder state, spore-mediated transmission, and severe disease in immunocompromised hosts.

    Trevor D. Lawley;Simon Clare;Alan W. Walker;David Goulding

  • Reprogramming of T Cells to Natural Killer–Like Cells upon Bcl11b Deletion

    Peng Li;Shannon Burke;Juexuan Wang;Xiongfeng Chen

  • Interaction of Salmonella enterica Serovar Typhimurium with Intestinal Organoids Derived from Human Induced Pluripotent Stem Cells

    Jessica L. Forbester;David Goulding;Ludovic Vallier;Ludovic Vallier;Nicholas Hannan

  • Epithelial IL-22RA1-Mediated Fucosylation Promotes Intestinal Colonization Resistance to an Opportunistic Pathogen

    Tu Anh N. Pham;Simon Clare;David Goulding;Julia M. Arasteh

  • Proteomic and Genomic Characterization of Highly Infectious Clostridium difficile 630 Spores

    Trevor D. Lawley;Nicholas J. Croucher;Lu Yu;Simon Clare

  • Clathrin-mediated endocytosis is essential in Trypanosoma brucei.

    Clare L. Allen;David Goulding;Mark C. Field

  • The central Z-disk region of titin is assembled from a novel repeat in variable copy numbers

    Mathias Gautel;David Goulding;Belinda Bullard;Klaus Weber

  • A Knockout Screen of ApiAP2 Genes Reveals Networks of Interacting Transcriptional Regulators Controlling the Plasmodium Life Cycle

    Katarzyna Modrzynska;Claudia Pfander;Lia Chappell;Lu Yu

  • Myristoyl-CoA:Protein N-Myristoyltransferase, an Essential Enzyme and Potential Drug Target in Kinetoplastid Parasites

    Helen P. Price;Malini R. Menon;Chrysoula Panethymitaki;David Goulding

  • A cyclic GMP signalling module that regulates gliding motility in a malaria parasite.

    Robert W. Moon;Cathy J. Taylor;Claudia Bex;Rebecca Schepers

  • Analysis of Protein Palmitoylation Reveals a Pervasive Role in Plasmodium Development and Pathogenesis

    Matthew L. Jones;Mark O. Collins;David Goulding;Jyoti S. Choudhary

  • A Plasmodium Calcium-Dependent Protein Kinase Controls Zygote Development and Transmission by Translationally Activating Repressed mRNAs

    Sarah Sebastian;Mathieu Brochet;Mark O. Collins;Frank Schwach

  • Functional redundancy of Rab27 proteins and the pathogenesis of Griscelli syndrome

    Duarte C. Barral;José S. Ramalho;Ross Anders;Alistair N. Hume

  • Convergent extension movements and ciliary function are mediated by ofd1 , a zebrafish orthologue of the human oral-facial-digital type 1 syndrome gene

    Maria I. Ferrante;Leila Romio;Silvia Castro;John E. Collins

  • Use of Purified Clostridium difficile Spores To Facilitate Evaluation of Health Care Disinfection Regimens

    Trevor D. Lawley;Simon Clare;Laura J. Deakin;David Goulding

  • A molecular map of titin/connectin elasticity reveals two different mechanisms acting in series.

    Mathias Gautel;David Goulding

Frequent Co-Authors

Gordon Dougan
Gordon Dougan University of Cambridge
Simon Clare
Simon Clare Wellcome Sanger Institute
Nicholas R. Thomson
Nicholas R. Thomson Wellcome Sanger Institute
Jyoti S. Choudhary
Jyoti S. Choudhary Institute of Cancer Research
Julian Parkhill
Julian Parkhill University of Cambridge
Trevor D. Lawley
Trevor D. Lawley Wellcome Sanger Institute
Stephen Baker
Stephen Baker Agency for Science, Technology and Research
Robert A. Kingsley
Robert A. Kingsley University of East Anglia
Paul Kellam
Paul Kellam Imperial College London
Gavin J. Wright
Gavin J. Wright Wellcome Sanger Institute

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