Stephanie L. James

Overview

Best Publications

• IL-10 inhibits parasite killing and nitrogen oxide production by IFN-gamma-activated macrophages.

  R T Gazzinelli;I P Oswald;S L James;A Sher

  927
  Citations

• Funding for malaria genome sequencing

  Stephen L. Hoffman;William H. Bancroft;Gottlieb Michael;Stephanie L. James

  696
  Citations

• The microbicidal activity of interferon-gamma-treated macrophages against Trypanosoma cruzi involves an L-arginine-dependent, nitrogen oxide-mediated mechanism inhibitable by interleukin-10 and transforming growth factor-beta.

  Ricardo T. Gazzinelli;Isabel P. Oswald;Sara Hieny;Stephanie L. James

  642
  Citations

• Role of T-cell derived cytokines in the downregulation of immune responses in parasitic and retroviral infection.

  Alan Sher;Ricardo T. Gazzinelli;Isabelle P. Oswald;Mario Clerici

  609
  Citations

• IL-10 synergizes with IL-4 and transforming growth factor-beta to inhibit macrophage cytotoxic activity.

  I P Oswald;R T Gazzinelli;A Sher;S L James

  535
  Citations

• Interleukin 10 inhibits macrophage microbicidal activity by blocking the endogenous production of tumor necrosis factor alpha required as a costimulatory factor for interferon gamma-induced activation.

  Isabelle P. Oswald;Thomas A. Wynn;Alan Sher;Stephanie L. James

  502
  Citations

• Macrophage cytotoxicity against schistosomula of Schistosoma mansoni involves arginine-dependent production of reactive nitrogen intermediates.

  S L James;J Glaven

  443
  Citations

• Induction of protective immunity against Schistosoma mansoni by vaccination with schistosome paramyosin (Sm97), a nonsurface parasite antigen.

  E J Pearce;S L James;S Hieny;D E Lanar

  331
  Citations

• Role of nitric oxide in parasitic infections

  Unknown

  329
  Citations

• Identification of paramyosin as schistosome antigen recognized by intradermally vaccinated mice.

  David E. Lanar;Edward J. Pearce;Stephanie L. James;Alan Sher

  232
  Citations

• Pathway to Deployment of Gene Drive Mosquitoes as a Potential Biocontrol Tool for Elimination of Malaria in Sub-Saharan Africa: Recommendations of a Scientific Working Group

  Stephanie James;Frank H. Collins;Philip A. Welkhoff;Claudia Emerson

  229
  Citations

• Studies with Double Cytokine-Deficient Mice Reveal That Highly Polarized Th1- and Th2-Type Cytokine and Antibody Responses Contribute Equally to Vaccine-Induced Immunity to Schistosoma mansoni

  Karl F. Hoffmann;Stephanie L. James;Allen W. Cheever;Thomas A. Wynn

  199
  Citations

• Optimal vaccination against Schistosoma mansoni requires the induction of both B cell- and IFN-gamma-dependent effector mechanisms.

  Dragana Jankovic;Thomas A. Wynn;Marika C. Kullberg;Sara Hieny

  196
  Citations

• Mechanisms of protective immunity against Schistosoma mansoni infection in mice vaccinated with irradiated cercariae. II. Analysis of immunity in hosts deficient in T lymphocytes, B lymphocytes, or complement.

  A Sher;S Hieny;S L James;R Asofsky

  186
  Citations

• ELEVATED EXPRESSION OF TH1 CYTOKINES AND NITRIC OXIDE SYNTHASE IN THE LUNGS OF VACCINATED MICE AFTER CHALLENGE INFECTION WITH SCHISTOSOMA MANSONI

  Thomas A. Wynn;Isabelle P. Oswald;Isam A. Eltoum;Patricia Caspar

  163
  Citations

• IL-12 enhances vaccine-induced immunity to schistosomes by augmenting both humoral and cell-mediated immune responses against the parasite.

  T A Wynn;A Reynolds;S James;A W Cheever

  160
  Citations

• Endothelial cells are activated by cytokine treatment to kill an intravascular parasite, Schistosoma mansoni, through the production of nitric oxide

  Isabelle P. Oswald;Isam Eltoum;Thomas A. Wynn;Bertrand Schwartz

  154
  Citations

• Immunochemical characterization and purification of Sm-97, a Schistosoma mansoni antigen monospecifically recognized by antibodies from mice protectively immunized with a nonliving vaccine.

  E J Pearce;S L James;J Dalton;A Barrall

  128
  Citations

• Comparison of Th1- and Th2-associated immune reactivities stimulated by single versus multiple vaccination of mice with irradiated Schistosoma mansoni cercariae.

  Z Caulada-Benedetti;F al-Zamel;A Sher;S James

  115
  Citations

• Guidance for contained field trials of vector mosquitoes engineered to contain a gene drive system: recommendations of a scientific working group

  Mark Benedict;Peter D'Abbs;Stephen Dobson;Michael Gottlieb

  107
  Citations

• The respiratory burst is not required for killing of intracellular and extracellular parasites by a lymphokine-activated macrophage cell line

  Phillip Scott;Stephanie James;Alan Sher

  106
  Citations

• NO as an effector molecule of parasite killing: modulation of its synthesis by cytokines.

  I.P. Oswald;T.A. Wynn;A. Sher;S.L. James

  104
  Citations

• Guidance framework for testing of genetically modified mosquitoes

  Mark Benedict;Mike Bonsall;Anthony A James;Stephanie James

  103
  Citations

• The role of nitrogen oxides as effector molecules of parasite killing

  S.L. James;J.B. Hibbs

  102
  Citations