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Microbiology

D-Index
86
Citations
32004
World Ranking
826
National Ranking
383

Overview

Richard R. Hardy was affiliated with Fox Chase Cancer Center in the United States. Their research primarily focused on medicine, with significant contributions in biochemistry, genetics, and molecular biology. The scientist's work also intersected with several subfields including radiology, nuclear medicine, imaging, oncology, genetics, molecular biology, and pulmonary and respiratory medicine.

Their research covered key topics related to cancer therapy and treatment, particularly centered on mechanisms of DNA repair and targeted therapeutics. Main areas of study included:

  • PARP inhibition in cancer therapy
  • BRCA gene mutations in cancer
  • DNA repair mechanisms
  • Prostate cancer treatment and research
  • Radiopharmaceutical chemistry and applications
  • Boron compounds in chemistry

Richard R. Hardy co-authored publications with the following frequent collaborators:

  • Jean Abraham
  • Lenka Oplustil O'Connor
  • Louise Grybowicz
  • Karen Pinilla
  • Alimu Dayimu

Their work was published in journals such as:

  • Nature Communications
  • Journal of Clinical Oncology

Recent publications included:

  • Neoadjuvant PARP inhibitor scheduling in BRCA1 and BRCA2 related breast cancer: PARTNER, a randomized phase II/III trial, 2025, Nature Communications
  • Time from medication order to administration of cabazitaxel (C) vs. lutetium Lu-177 vipivotide tetraxetan (Lu) in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC), 2025, Journal of Clinical Oncology

Best Publications

  • Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow.

    Richard R. Hardy;Condie E. Carmack;Susan A. Shinton;John D. Kemp

  • B cell development pathways.

    Richard R. Hardy;Kyoko Hayakawa

  • Notch1 expression in early lymphopoiesis influences B versus T lineage determination.

    John C Pui;David Allman;Lanwei Xu;Susan DeRocco

  • The "Ly-1 B" cell subpopulation in normal immunodefective, and autoimmune mice.

    Kyoko Hayakawa;Richard R. Hardy;David R. Parks;Leonore A. Herzenberg

  • Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression

    Carlo M. Croce

  • Ly-1 B cells: functionally distinct lymphocytes that secrete IgM autoantibodies.

    K Hayakawa;R R Hardy;M Honda;L A Herzenberg

  • Progenitors for Ly-1 B cells are distinct from progenitors for other B cells.

    K Hayakawa;R R Hardy;L A Herzenberg

  • The Regulated Expression of B Lineage Associated Genes during B Cell Differentiation in Bone Marrow and Fetal Liver

    Yue-Sheng Li;Kyoko Hayakawa;Richard R. Hardy

  • Resolution of Three Nonproliferative Immature Splenic B Cell Subsets Reveals Multiple Selection Points During Peripheral B Cell Maturation

    David Allman;R. Coleman Lindsley;William DeMuth;Kristina Rudd

  • Positive selection of natural autoreactive B cells.

    Kyoko Hayakawa;Masanao Asano;Susan A. Shinton;Ming Gui

  • Rheumatoid factor secretion from human Leu-1+ B cells

    Richard R. Hardy;Kyoko Hayakawa;Masatoshi Shimizu;Katsuhiko Yamasaki

  • Expression of anti-DNA immunoglobulin transgenes in non-autoimmune mice.

    Jan Erikson;Marko Z. Radic;Sally A. Camper;Richard R. Hardy

  • Identification of the Earliest B Lineage Stage in Mouse Bone Marrow

    Yue-Sheng Li;Robert Wasserman;Kyoko Hayakawa;Richard R. Hardy

  • Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice.

    Eugenia Spanopoulou;Christopher A. J. Roman;Lynn M. Corcoran;Mark S. Schlissel

  • Molecular structure of human lymphocyte receptor for immunoglobulin E

    Hitoshi Kikutani;Seiji Inui;Ryoichi Sato;Edward L. Barsumian

  • Receptors for B cell stimulatory factor 2. Quantitation, specificity, distribution, and regulation of their expression

    T Taga;Y Kawanishi;R R Hardy;T Hirano

  • Surface phenotype of Peyer's patch germinal center cells: implications for the role of germinal centers in B cell differentiation.

    Eugene C. Butcher;Robert V. Rouse;Robert L. Coffman;Carol N. Nottenburg

  • Normal, Autoimmune, and Malignant CD5+ B Cells: The LY-1 B Lineage?

    Kyoko Hayakawa;Richard R. Hardy

  • Peritoneal Ly-1 B cells: genetic control, autoantibody production, increased lambda light chain expression.

    Kyoko Hayakawa;Richard R. Hardy;Leonore A. Herzenberg

  • Production of immunoglobulin isotypes by Ly-1+ B cells in viable motheaten and normal mice.

    Charles L. Sidman;Leonard D. Shultz;Richard R. Hardy;Kyoko Hayakawa

  • Development and physiology of Ly-1 B and its human homolog, Leu-1 B.

    Richard R. Hardy;Kyoko Hayakawa

Frequent Co-Authors

Kyoko Hayakawa
Kyoko Hayakawa Fox Chase Cancer Center
David Allman
David Allman University of Pennsylvania
Diane Mathis
Diane Mathis Harvard University
Mark S. Schlissel
Mark S. Schlissel University of California, Berkeley
Christophe Benoist
Christophe Benoist Harvard University
Tadamitsu Kishimoto
Tadamitsu Kishimoto Osaka University
Daphne Koller
Daphne Koller insitro Inc.
Miriam Merad
Miriam Merad Icahn School of Medicine at Mount Sinai
Leonore A. Herzenberg
Leonore A. Herzenberg Stanford University
Aviv Regev
Aviv Regev Genentech

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