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Immunology

D-Index
50
Citations
15240
World Ranking
4190
National Ranking
1912

Overview

Peter A. Sieling is affiliated with the University of California, Los Angeles in the United States. Their research focuses on multiple areas within medicine, biochemistry, genetics, molecular biology, immunology, and microbiology. The scientist's work spans several subfields including infectious diseases, immunology, genetics, molecular biology, and oncology.

The recent publication record of Peter A. Sieling reflects a strong emphasis on SARS-CoV-2 and COVID-19 research as well as immunotherapy and immune responses. Their scholarly output covers virus-based gene therapy and CAR-T cell therapy research, alongside COVID-19 clinical research studies, mitochondrial function and pathology, and the development of vaccines and immunoinformatics approaches.

Key recent papers authored by or co-authored with Peter A. Sieling include:

  • Pressure-Driven Mitochondrial Transfer Pipeline Generates Mammalian Cells of Desired Genetic Combinations and Fates, 2020, Cell Reports
  • Intranasal plus subcutaneous prime vaccination with a dual antigen COVID-19 vaccine elicits T-cell and antibody responses in mice, 2021, Scientific Reports
  • A Next Generation Bivalent Human Ad5 COVID-19 Vaccine Delivering Both Spike and Nucleocapsid Antigens Elicits Th1 Dominant CD4+, CD8+ T-cell and Neutralizing Antibody Responses, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Dual-Antigen COVID-19 Vaccine Subcutaneous Prime Delivery With Oral Boosts Protects NHP Against SARS-CoV-2 Challenge, 2021, Frontiers in Immunology
  • Complete Protection of Nasal and Lung Airways Against SARS-CoV-2 Challenge by Antibody Plus Th1 Dominant N- and S-Specific T-Cell Responses to Subcutaneous Prime and Thermally-Stable Oral Boost Bivalent hAd5 Vaccination in an NHP Study, 2020, bioRxiv (Cold Spring Harbor Laboratory)

Frequent co-authors of Peter A. Sieling are:

  • Shahrooz Rabizadeh
  • Kayvan Niazi
  • Adrian Rice
  • Annie Shin
  • Lise Zakin

The most common publication venues for their work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Regular and Young Investigator Award Abstracts
  • Cell Reports
  • Scientific Reports
  • Frontiers in Immunology

Main fields of study represented in Peter A. Sieling's research contributions are:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology
  • Immunology and Microbiology

Areas of specialized interest based on subfields include:

  • Infectious Diseases
  • Immunology
  • Genetics
  • Molecular Biology
  • Oncology

Principal research topics explored are:

  • SARS-CoV-2 and COVID-19 Research
  • Immunotherapy and Immune Responses
  • Virus-based gene therapy research
  • CAR-T cell therapy research
  • COVID-19 Clinical Research Studies
  • Vaccines and immunoinformatics approaches
  • Mitochondrial Function and Pathology

Best Publications

  • Induction of Direct Antimicrobial Activity Through Mammalian Toll-Like Receptors

    Sybille Thoma-Uszynski;Steffen Stenger;Osamu Takeuchi;Maria Teresa Ochoa

  • CD1-restricted T cell recognition of microbial lipoglycan antigens.

    P. A. Sieling;D. Chatterjee;S. A. Porcelli;T. I. Prigozy

  • Activation of Toll-Like Receptor 2 in Acne Triggers Inflammatory Cytokine Responses

    Jenny Kim;Maria-Teresa Ochoa;Stephan R. Krutzik;Osamu Takeuchi

  • Bacterial Lipopolysaccharide Activates NF-κB through Toll-like Receptor 4 (TLR-4) in Cultured Human Dermal Endothelial Cells DIFFERENTIAL EXPRESSION OF TLR-4 AND TLR-2 IN ENDOTHELIAL CELLS

    Emmanuelle Faure;Ozlem Equils;Peter A. Sieling;Lisa Thomas

  • Apoptosis facilitates antigen presentation to T lymphocytes through MHC-I and CD1 in tuberculosis

    Ulrich E Schaible;Florian Winau;Peter A Sieling;Karsten Fischer

  • Vitamin D Is Required for IFN-γ–Mediated Antimicrobial Activity of Human Macrophages

    Mario Fabri;Steffen Stenger;Dong Min Shin;Jae Min Yuk

  • Microbial Dysbiosis Is Associated with Human Breast Cancer

    Caiyun Xuan;Jaime M. Shamonki;Alice Chung;Maggie L. DiNome

  • TLR activation triggers the rapid differentiation of monocytes into macrophages and dendritic cells

    Stephan R Krutzik;Belinda Tan;Huiying Li;Maria Teresa Ochoa

  • Ito cells are liver-resident antigen-presenting cells for activating T cell responses.

    Florian Winau;Guido Hegasy;Ralf Weiskirchen;Stephan Weber

  • Structural requirements for glycolipid antigen recognition by CD1b-restricted T cells.

    D. Branch Moody;Bruce B. Reinhold;Mark R. Guy;Evan M. Beckman

  • A Role for Triggering Receptor Expressed on Myeloid Cells-1 in Host Defense During the Early-Induced and Adaptive Phases of the Immune Response

    Joshua R. Bleharski;Viviane Kiessler;Cecilia Buonsanti;Peter A. Sieling

  • Activation and regulation of Toll-like receptors 2 and 1 in human leprosy.

    Stephan R. Krutzik;Maria Teresa Ochoa;Peter A. Sieling;Satoshi Uematsu

  • The Mannose Receptor Delivers Lipoglycan Antigens to Endosomes for Presentation to T Cells by CD1b Molecules

    Theodore I Prigozy;Peter A Sieling;Daniel Clemens;Phoebe L Stewart

  • Langerhans cells utilize CD1a and langerin to efficiently present nonpeptide antigens to T cells

    Robert E. Hunger;Peter A. Sieling;Maria Teresa Ochoa;Makoto Sugaya

  • Immunosuppressive roles for IL-10 and IL-4 in human infection. In vitro modulation of T cell responses in leprosy.

    P A Sieling;J S Abrams;M Yamamura;P Salgame

  • CD1-Restricted Microbial Lipid Antigen-Specific Recognition Found in the CD8+ αβ T Cell Pool

    Jean Pierre Rosat;Ethan P. Grant;Evan M. Beckman;Christopher C. Dascher

  • CD1c restricts responses of mycobacteria-specific T cells. Evidence for antigen presentation by a second member of the human CD1 family.

    Evan M. Beckman;Agustín Melián;Samuel M. Behar;Peter A. Sieling

  • T-cell release of granulysin contributes to host defense in leprosy.

    Maria Teresa Ochoa;Steffen Stenger;Peter A. Sieling;Sybille Thoma-Uszynski

  • Expression of Toll-like receptor 2 on human Schwann cells: a mechanism of nerve damage in leprosy

    Rosane B. Oliveira;Maria T. Ochoa;Peter A. Sieling;Thomas H. Rea

  • TGF-α Regulates TLR Expression and Function on Epidermal Keratinocytes

    Lloyd S. Miller;Ole E. Sørensen;Philip T. Liu;H. Ray Jalian

Frequent Co-Authors

Robert L. Modlin
Robert L. Modlin University of California, Los Angeles
Thomas H. Rea
Thomas H. Rea University of Southern California
Steven A. Porcelli
Steven A. Porcelli Albert Einstein College of Medicine
Barry R. Bloom
Barry R. Bloom Harvard University
Steffen Stenger
Steffen Stenger University of Ulm
Patrick J. Brennan
Patrick J. Brennan Colorado State University
Stefan H. E. Kaufmann
Stefan H. E. Kaufmann Max Planck Institute for Infection Biology
John T. Belisle
John T. Belisle Colorado State University
Ulrich E. Schaible
Ulrich E. Schaible Research Center Borstel - Leibniz-Center for Medicine and Biosciences
Euzenir Nunes Sarno
Euzenir Nunes Sarno Oswaldo Cruz Foundation

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