Cell biology, Desmosome assembly, Wnt signaling pathway, Cadherin and Cell adhesion are her primary areas of study. The concepts of her Cell biology study are interwoven with issues in Desmosomal Cadherins, Adherens junction and Cytoskeleton. Her Desmosome assembly research integrates issues from University medical, Desmosome, Desmocollins and Plakoglobin.
Her study looks at the relationship between Wnt signaling pathway and topics such as Cell type, which overlap with Stem cell and Carcinogenesis. Her Cadherin research includes themes of Cell aggregation, Cell adhesion molecule and Cell–cell interaction. Her Beta-catenin research includes elements of Internal medicine, Endocrinology and Cancer research.
Her primary areas of investigation include Cell biology, Cadherin, Desmosome, Plakoglobin and Wnt signaling pathway. She has included themes like Embryonic stem cell, Cell junction, Cell adhesion, Cytoskeleton and Adherens junction in her Cell biology study. Her research in Cadherin intersects with topics in Cell adhesion molecule and Cell–cell interaction.
Her study in Desmosome is interdisciplinary in nature, drawing from both Ultrastructure, Desmoplakins, Molecular biology, Peptide sequence and Membrane protein. The various areas that Pamela Cowin examines in her Plakoglobin study include Desmosomal Cadherins and Cell type. Her Wnt signaling pathway research is multidisciplinary, incorporating perspectives in Endocrinology, Internal medicine and Cancer research.
Her primary areas of study are Cell biology, Wnt signaling pathway, Embryonic stem cell, Cancer research and Mammary gland. Pamela Cowin combines Cell biology and Drug development in her research. In her research on the topic of Wnt signaling pathway, Gene expression, Progenitor cell, Transcription factor and Stem cell is strongly related with Hedgehog.
Her work carried out in the field of Cancer research brings together such families of science as Fibronectin, Extracellular matrix, Fibrillin and Transforming growth factor beta, Latent TGF-beta binding protein. Her Mammary gland research is multidisciplinary, relying on both Estrogen receptor and Prostate cancer, Androgen receptor. Pamela Cowin has researched Morphogenesis in several fields, including Integrin, G protein-coupled receptor, Cell adhesion and Transmembrane domain.
Pamela Cowin spends much of her time researching Cancer research, Wnt signaling pathway, Latent TGF-beta binding protein, Transforming growth factor beta and Extracellular matrix. Pamela Cowin interconnects HEK 293 cells, Cell, Regulation of gene expression and microRNA in the investigation of issues within Cancer research. Her Wnt signaling pathway research entails a greater understanding of Cell biology.
Her work deals with themes such as Epithelial–mesenchymal transition, Metastasis, Fibronectin and Fibrillin, which intersect with Latent TGF-beta binding protein.
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Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells
Yi Li;Bryan Welm;Katrina Podsypanina;Shixia Huang.
Proceedings of the National Academy of Sciences of the United States of America (2003)
Plakoglobin: a protein common to different kinds of intercellular adhering junctions.
Pamela Cowin;Hans Peter Kapprell;Werner W. Franke;John Tamkun.
Cadherins and catenins in breast cancer
Pamela Cowin;Tracey M Rowlands;Sarah J Hatsell.
Current Opinion in Cell Biology (2005)
Expression of Wnt-1 in PC12 cells results in modulation of plakoglobin and E-cadherin and increased cellular adhesion.
Roger S. Bradley;Pamela Cowin;Anthony M. C. Brown.
Journal of Cell Biology (1993)
Nomenclature of the desmosomal cadherins.
R S Buxton;P Cowin;W W Franke;D R Garrod.
Journal of Cell Biology (1993)
Untangling Desmosomal Knots with Electron Tomography
Wanzhong He;Pamela Cowin;David L. Stokes.
Pam Cowin;Brian Burke.
Current Opinion in Cell Biology (1996)
Molecular cloning and amino acid sequence of human plakoglobin, the common junctional plaque protein
Werner W. Franke;Michaela D. Goldschmidt;Ralf Zimbelmann;Hubert M. Mueller.
Proceedings of the National Academy of Sciences of the United States of America (1989)
Δn89β-Catenin Induces Precocious Development, Differentiation, and Neoplasia in Mammary Gland
Alexandra Imbert;Rachel Eelkema;Sara Jordan;Helen Feiner.
Journal of Cell Biology (2001)
β-catenin and tcfs in mammary development and cancer
Sarah Hatsell;Tracey Rowlands;Minoti Hiremath;Pamela Cowin.
Journal of Mammary Gland Biology and Neoplasia (2003)
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