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Animal Science and Veterinary

D-Index
22
Citations
1346
World Ranking
3122
National Ranking
15

Overview

P. K. Murthy is affiliated with the University of Lucknow in India. Their research focuses primarily on infectious diseases and parasitology, with interdisciplinary contributions in insect science, molecular biology, and biotechnology. The scientist's work spans the intersection of parasitic diseases research, host-parasite interactions, and biological influences on insect symbiosis.

The main fields of study for P. K. Murthy include:

  • Medicine
  • Agricultural and Biological Sciences

Subfields they have contributed to are:

  • Infectious Diseases
  • Insect Science
  • Parasitology
  • Molecular Biology
  • Biotechnology

The primary research topics covered in their publications are:

  • Parasitic Diseases Research and Treatment
  • Insect symbiosis and bacterial influences
  • Parasites and Host Interactions
  • Studies on Chitinases and Chitosanases
  • Transgenic Plants and Applications

P. K. Murthy has authored and co-authored multiple scientific papers, mostly published in the journal Acta Parasitologica, with additional work appearing in Vaccine. Their recent papers include:

  • Immunolocalization of Disorganized Muscle Protein-1 in Different Life Stages of Human Lymphatic Filariid, Brugia malayi (2020, Acta Parasitologica)
  • Immune Response Profiling of Cocktails of Brugia malayi Vaccine Candidates DIM-1, Calponin and Troponin 1 in BALB/c Mice (2023, Acta Parasitologica)
  • Immunoreactivity of Brugia malayi Calreticulin and Its Domains with Sera of Different Categories of Bancroftian Filarial Patients (2022, Acta Parasitologica)
  • Corrigendum to 'Protection against filarial infection by 45-49 kDa molecules of Brugia malayi via IFN-γ-mediated iNOS induction' [Vaccine 33 (2015) 527-534] (2020, Vaccine)

Frequent collaborators in their research work include:

  • Vikas Kushwaha
  • Prachi Tewari
  • Payal Mandal
  • Amogh A. Sahasrabuddhe
  • Sunita Yadav

P. K. Murthy's research demonstrates a consistent focus on parasitic diseases, particularly those caused by Brugia malayi. Their work includes immunological profiling and molecular characterization aimed at understanding host immune responses and vaccine candidate evaluation. The scientist's involvement across diverse subfields indicates an integrative approach combining biological sciences and medical research to address infectious disease challenges.

Best Publications

  • Interleukin-10 modulates proinflammatory cytokines in the human monocytic cell line THP-1 stimulated with Borrelia burgdorferi lipoproteins.

    P. K. Murthy;Vida A. Dennis;Barbara L. Lasater;Mario T. Philipp

  • Antifilarial activity in vitro and in vivo of some flavonoids tested against Brugia malayi.

    V. Lakshmi;S.K. Joseph;S. Srivastava;S.K. Verma

  • Comparison of humoral and cell-mediated immune responses to cationic PLGA microspheres containing recombinant hepatitis B antigen

    Vinay Saini;Vikas Jain;M.S. Sudheesh;K.S. Jaganathan

  • Autocrine and Exocrine Regulation of Interleukin-10 Production in THP-1 Cells Stimulated with Borrelia burgdorferi Lipoproteins

    Guillermo H. Giambartolomei;Vida A. Dennis;Barbara L. Lasater;P. K. Murthy

  • Integrated Dataset of Screening Hits against Multiple Neglected Disease Pathogens

    Solomon Nwaka;Solomon Nwaka;Dominique Besson;Bernadette Ramirez;Louis Maes

  • Synthesis and antifilarial activity of chalcone-thiazole derivatives against a human lymphatic filarial parasite, Brugia malayi.

    Koneni V. Sashidhara;K. Bhaskara Rao;Vikas Kushwaha;Ram K. Modukuri

  • Plant products in the treatment and control of filariasis and other helminth infections and assay systems for antifilarial/anthelmintic activity.

    Puvvada Kalpana Murthy;Sujith Kurian Joseph;Puvvada Sri Ramchandra Murthy

  • Fate of infective larvae of Brugia malayi in the peritoneal cavity of Mastomys natalensis and Meriones unguiculatus.

    Puvvada Kalpana Murthy;Puvvada Sri Ramchandra Murthy;K. Tyagi;R. K. Chatterjee

  • Protection against L3 induced Brugia malayi infection in Mastomys coucha pre-immunized with BmAFII fraction of the filarial adult worm.

    S. Dixit;R.L. Gaur;M.K. Sahoo;S.K. Joseph

  • Antifilarial activity of some 2H-1-benzopyran-2-ones (coumarins).

    R.P Tripathi;R Tripathi;A.P Bhaduri;S.N Singh

  • The antifilarial activity of a marine red alga, Botryocladia leptopoda , against experimental infections with animal and human filariae

    V. Lakshmi;R. Kumar;P. Gupta;V. Varshney

  • Poorer NF‐κB signaling by microfilariae in macrophages from BALB/c mice affects their ability to produce cytotoxic levels of nitric oxide to kill microfilariae

    Sangita Mukhopadhyay;V.M.L. Srivastava;P.K. Murthy;Seyed E. Hasnain

  • Anti-filarial activity of novel formulations of albendazole against experimental brugian filariasis.

    R. L. Gaur;S. Dixit;M. K. Sahoo;M. Khanna

  • Sensitization with anti-inflammatory BmAFI of Brugia malayi allows L3 development in the hostile peritoneal cavity of Mastomys coucha

    S.K. Joseph;S.K. Verma;M.K. Sahoo;S. Dixit

  • Inflammatory antigens of Brugia malayi and their effect on rodent host Mastomys coucha.

    S. Dixit;R. L. Gaur;M. A. Khan;J. K. Saxena

  • Influence of Brugia malayi life stages and BmAFII fraction on experimental Leishmania donovani infection in hamsters.

    P.K. Murthy;S. Dixit;R.L. Gaur;Ramesh Kumar

  • Efficacy of a substituted methyl benzimidazole carbamate against developing and adult helminth parasites.

    J.C. Katiyar;Anuradha Misra;Suman Gupta;P.K.S. Visen

  • Antifilarial efficacy of Hibiscus sabdariffa on lymphatic filarial parasite Brugia malayi

    K. Saxena;V. Dube;V. Kushwaha;V. Gupta

  • Studies in potential filaricides. 18. Synthesis of 2,2'-disubstituted 5,5'-dibenzimidazolyl ketones and related compounds as potential anthelmintics.

    Syed Abuzar;Satyavan Sharma;Nigar Fatma;S. Gupta

  • Cross reactive molecules of human lymphatic filaria Brugia malayi inhibit Leishmania donovani infection in hamsters

    Richa Verma;Sujith K. Joseph;Vikas Kushwaha;Vikash Kumar

  • Presbytis entellus: a primate model for parasitic disease research.

    Anuradha Dube;Puvvada Kalpana Murthy;Sunil Kumar Puri;Shailja Misra-Bhattacharya

  • Inflammatory mediator release by Brugia malayi from macrophages of susceptible host Mastomys coucha and THP-1 and RAW 264.7 cell lines.

    Shiv Kumar Verma;Vikas Kushwaha;Vijaya Dubey;Kirti Saxena

  • Effect of short- and long-term immunization of recombinant disorganized muscle protein-1 (rDIM-1) against human filarial parasite Brugia malayi in rodents

    Vikas Kushwaha;Puvvada Kalpana Murthy

  • Corrigendum to "Cross reactive molecules of human lymphatic filaria Brugia malayi inhibit Leishmania donovani infection in hamsters" [Acta Trop. 152 (2015) 103-111].

    Richa Verma;Sujith K. Joseph;Vikas Kushwaha;Vikash Kumar

Frequent Co-Authors

Ramesh Chandra
Ramesh Chandra University of Delhi
Brajesh K. Singh
Brajesh K. Singh Western Sydney University
Mario T. Philipp
Mario T. Philipp Tulane University
Prem M. S. Chauhan
Prem M. S. Chauhan Central Drug Research Institute
Sandeep Verma
Sandeep Verma Indian Institute of Technology Kanpur
Timothy G. Geary
Timothy G. Geary McGill University
Sunil K. Puri
Sunil K. Puri Central Drug Research Institute
Quentin D. Bickle
Quentin D. Bickle London School of Hygiene & Tropical Medicine
Louis Maes
Louis Maes University of Antwerp
Wesley C. Van Voorhis
Wesley C. Van Voorhis University of Washington

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