World's Best Scientists 2026 revealed!

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Immunology

D-Index
56
Citations
15160
World Ranking
3684
National Ranking
1697

Overview

Nicole Frahm is affiliated with the Fred Hutchinson Cancer Research Center in the United States. Their research spans areas primarily within immunology, microbiology, and medicine, with a strong focus on infectious diseases and virology. The subfields that characterize their work include immunology, infectious diseases, virology, epidemiology, and molecular biology.

The scientist's research covers key topics such as HIV research and treatment, tuberculosis research and epidemiology, mycobacterium research and diagnosis, immune cell function and interaction, T-cell and B-cell immunology, vaccines and immunoinformatics approaches, as well as immunotherapy and immune responses.

Nicole Frahm has published multiple papers in notable scientific journals. Recent publications include:

  • "Tuberculosis Treatment Monitoring and Outcome Measures: New Interest and New Strategies" (2022, Clinical Microbiology Reviews)
  • "Update on the Diagnosis of Tuberculosis" (2023, Clinical Microbiology and Infection)
  • "Safety and Immune Responses after a 12-month Booster in Healthy HIV-Uninfected Adults in HVTN 100 in South Africa: A Randomized Double-Blind Placebo-Controlled Trial of ALVAC-HIV (vCP2438) and Bivalent Subtype C gp120/MF59 Vaccines" (2020, PLoS Medicine)
  • "Phase 1 Human Immunodeficiency Virus (HIV) Vaccine Trial to Evaluate the Safety and Immunogenicity of HIV Subtype C DNA and MF59-Adjuvanted Subtype C Envelope Protein" (2020, Clinical Infectious Diseases)
  • "The Quest for Vaccine-Induced Immune Correlates of Protection against Tuberculosis" (2022, Vaccine Insights)

Frequently, Nicole Frahm collaborates with colleagues in the field. Some of the most common coauthors are:

  • M. Juliana McElrath
  • Georgia D. Tomaras
  • Zoe Moodie
  • Kristen W. Cohen
  • Peter B. Gilbert

The scientist's work is regularly published in venues including:

  • PLoS Medicine
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Clinical Microbiology Reviews
  • Clinical Microbiology and Infection
  • New England Journal of Medicine

Best Publications

  • Immune-Correlates Analysis of an HIV-1 Vaccine Efficacy Trial

    Barton F. Haynes;Peter B. Gilbert;M. Juliana McElrath;Susan Zolla-Pazner

  • The epigenetic landscape of T cell exhaustion

    Debattama R. Sen;James Kaminski;R. Anthony Barnitz;Makoto Kurachi

  • HLA class I supertypes: a revised and updated classification

    John Sidney;Bjoern Peters;Nicole Frahm;Christian Brander

  • Efficacy Trial of a DNA/rAd5 HIV-1 Preventive Vaccine

    Scott M. Hammer;Magdalena E. Sobieszczyk;Holly Janes;Shelly T. Karuna

  • Safety and Immunogenicity of Novel Adenovirus Type 26– and Modified Vaccinia Ankara–Vectored Ebola Vaccines: A Randomized Clinical Trial

    Iain D. Milligan;Malick M. Gibani;Richard Sewell;Elizabeth A. Clutterbuck

  • Relative Dominance of Gag p24-Specific Cytotoxic T Lymphocytes Is Associated with Human Immunodeficiency Virus Control

    Rosario Zuñiga;Aldo Lucchetti;Patricia Galvan;Shyla Sanchez

  • Dissecting Polyclonal Vaccine-Induced Humoral Immunity against HIV Using Systems Serology.

    Amy W. Chung;Amy W. Chung;Manu P. Kumar;Kelly B. Arnold;Wen Han Yu;Wen Han Yu

  • Consistent Cytotoxic-T-Lymphocyte Targeting of Immunodominant Regions in Human Immunodeficiency Virus across Multiple Ethnicities

    Nicole Frahm;B. T. Korber;B. T. Korber;C. M. Adams;J. J. Szinger

  • Evaluation of a mosaic HIV-1 vaccine in a multicentre, randomised, double-blind, placebo-controlled, phase 1/2a clinical trial (APPROACH) and in rhesus monkeys (NHP 13-19)

    Dan H Barouch;Dan H Barouch;Frank L Tomaka;Frank Wegmann;Daniel J Stieh

  • Founder effects in the assessment of HIV polymorphisms and HLA allele associations.

    Tanmoy Bhattacharya;Tanmoy Bhattacharya;Marcus Daniels;David Heckerman;Brian Foley

  • MyD88-Dependent Immune Activation Mediated by Human Immunodeficiency Virus Type 1-Encoded Toll-Like Receptor Ligands

    Angela Meier;Galit Alter;Nicole Frahm;Harlyn Sidhu

  • Induction of Robust Cellular and Humoral Virus-Specific Adaptive Immune Responses in Human Immunodeficiency Virus-Infected Humanized BLT Mice

    Diana M. Brainard;Edward Seung;Nicole Frahm;Nicole Frahm;Annaiah Cariappa

  • COMPASS identifies T-cell subsets correlated with clinical outcomes

    Lin Lin;Greg Finak;Kevin Ushey;Chetan Seshadri

  • HLA-B57/B*5801 Human Immunodeficiency Virus Type 1 Elite Controllers Select for Rare Gag Variants Associated with Reduced Viral Replication Capacity and Strong Cytotoxic T-Lymphocyte Recognition.

    Toshiyuki Miura;Mark A. Brockman;Arne Schneidewind;Michael Lobritz

  • Control of human immunodeficiency virus replication by cytotoxic T lymphocytes targeting subdominant epitopes.

    Nicole Frahm;Photini Kiepiela;Sharon Adams;Caitlyn H Linde

  • Genetic impact of vaccination on breakthrough HIV-1 sequences from the STEP trial

    Morgane Rolland;Sodsai Tovanabutra;Allan C deCamp;Nicole Frahm

  • Vaccine-elicited human T cells recognizing conserved protein regions inhibit HIV-1

    Nicola Borthwick;Tina Ahmed;Beatrice Ondondo;Peter Hayes

  • A Quantitative Analysis of the Variables Affecting the Repertoire of T Cell Specificities Recognized after Vaccinia Virus Infection

    Erika Assarsson;John Sidney;Carla Oseroff;Valerie Pasquetto

  • Evidence of Differential HLA Class I-Mediated Viral Evolution in Functional and Accessory/Regulatory Genes of HIV-1

    Zabrina L Brumme;Zabrina L Brumme;Zabrina L Brumme;Chanson J Brumme;Chanson J Brumme;David Heckerman;Bette T Korber;Bette T Korber

  • Comprehensive Analysis of Human Immunodeficiency Virus Type 1-Specific CD4 Responses Reveals Marked Immunodominance of gag and nef and the Presence of Broadly Recognized Peptides

    Daniel E. Kaufmann;Paul M. Bailey;John Sidney;Bradford Wagner

Frequent Co-Authors

Bruce D. Walker
Bruce D. Walker Harvard University
M. Juliana McElrath
M. Juliana McElrath University of Washington
Christian Brander
Christian Brander University of Vic - Central University of Catalonia
Peter B. Gilbert
Peter B. Gilbert Fred Hutchinson Cancer Research Center
Georgia D. Tomaras
Georgia D. Tomaras Duke University
Bette T. Korber
Bette T. Korber Los Alamos National Laboratory
Lawrence Corey
Lawrence Corey Fred Hutchinson Cancer Research Center
David Heckerman
David Heckerman Microsoft (United States)
Todd M. Allen
Todd M. Allen Harvard University
James I. Mullins
James I. Mullins University of Washington

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