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Chemistry

D-Index
51
Citations
12670
World Ranking
13796
National Ranking
3580

Research.com Recognitions

  • 2019 - Fellow of John Simon Guggenheim Memorial Foundation
  • 2017 - ACS Award in Pure Chemistry, American Chemical Society (ACS)

Overview

Neal K. Devaraj is a researcher affiliated with the University of California, San Diego in the United States. Their scholarly work is concentrated primarily within the field of Biochemistry, Genetics and Molecular Biology, with a significant focus on Molecular Biology as a subfield. The research also spans Cellular and Molecular Neuroscience, Organic Chemistry, Biomaterials, and Astronomy and Astrophysics.

The scientist's studies address major topics including Lipid Membrane Structure and Behavior, RNA and protein synthesis mechanisms, Photoreceptor and optogenetics research, RNA Interference and Gene Delivery, Supramolecular Self-Assembly in Materials, Click Chemistry and Applications, and advanced biosensing and bioanalysis techniques.

Devaraj has contributed to multiple notable publications. Some of the recent papers include:

  • Reversing a model of Parkinson's disease with in situ converted nigral neurons (2020, Nature)
  • Light-activated tetrazines enable precision live-cell bioorthogonal chemistry (2022, Nature Chemistry)
  • Synthesis of lipid membranes for artificial cells (2021, Nature Reviews Chemistry)
  • Enzyme-free synthesis of natural phospholipids in water (2020, Nature Chemistry)
  • Membrane Mimetic Chemistry in Artificial Cells (2021, Journal of the American Chemical Society)

Frequent collaboration partners include Roberto J. Brea, Alessandro Fracassi, Dongyang Zhang, Ahanjit Bhattacharya, and Christy J. Cho.

Devaraj's work is published predominantly in established scientific venues such as bioRxiv (Cold Spring Harbor Laboratory), Journal of the American Chemical Society, Nature Chemistry, ACS Chemical Biology, and Angewandte Chemie International Edition.

Awards received by the researcher include the ACS Award in Pure Chemistry from the American Chemical Society in 2017 and a fellowship from the John Simon Guggenheim Memorial Foundation awarded in 2019.

Best Publications

  • Tetrazine-based cycloadditions: application to pretargeted live cell imaging.

    Neal K. Devaraj;Ralph Weissleder;Scott A. Hilderbrand

  • "Clicking" functionality onto electrode surfaces.

    James P. Collman;Neal K. Devaraj;Christopher E. D. Chidsey

  • A Cytochrome c Oxidase Model Catalyzes Oxygen to Water Reduction Under Rate-Limiting Electron Flux

    James P. Collman;Neal K. Devaraj;Richard A. Decréau;Ying Yang

  • Biomedical applications of tetrazine cycloadditions.

    Neal K. Devaraj;Ralph Weissleder

  • The Future of Bioorthogonal Chemistry.

    Neal K. Devaraj

  • Bioorthogonal Turn‐On Probes for Imaging Small Molecules inside Living Cells

    Neal K. Devaraj;Scott Hilderbrand;Rabi Upadhyay;Ralph Mazitschek

  • Reversing a model of Parkinson’s disease with in situ converted nigral neurons

    Hao Qian;Xinjiang Kang;Jing Hu;Jing Hu;Dongyang Zhang

  • Mixed azide-terminated monolayers: a platform for modifying electrode surfaces.

    James P. Collman;Neal K. Devaraj;Todd P. A. Eberspacher;Christopher E. D. Chidsey

  • Fast and Sensitive Pretargeted Labeling of Cancer Cells through a Tetrazine/trans-Cyclooctene Cycloaddition†

    Neal K. Devaraj;Rabi Upadhyay;Jered B. Haun;Scott A. Hilderbrand

  • Bioorthogonal chemistry amplifies nanoparticle binding and enhances the sensitivity of cell detection

    Jered B. Haun;Neal K. Devaraj;Scott A. Hilderbrand;Hakho Lee

  • Live-Cell Imaging of Cyclopropene Tags with Fluorogenic Tetrazine Cycloadditions†

    Jun Yang;Jolita Šečkutė;Christian M. Cole;Neal K. Devaraj

  • 18F labeled nanoparticles for in vivo PET-CT imaging.

    Neal K. Devaraj;Edmund J. Keliher;Greg M. Thurber;Matthias Nahrendorf

  • Introduction: Click Chemistry.

    Neal K Devaraj;Neal K Devaraj;M G Finn;M G Finn

  • Chemoselective covalent coupling of oligonucleotide probes to self-assembled monolayers

    Neal K. Devaraj;Gregory P. Miller;Wataru Ebina;Boyko Kakaradov

  • Metal-Catalyzed One-Pot Synthesis of Tetrazines Directly from Aliphatic Nitriles and Hydrazine

    Jun Yang;Mark R. Karver;Weilong Li;Swagat Sahu

  • Advances in Tetrazine Bioorthogonal Chemistry Driven by the Synthesis of Novel Tetrazines and Dienophiles.

    Haoxing Wu;Neal K. Devaraj

  • Development of a Bioorthogonal and Highly Efficient Conjugation Method for Quantum Dots using Tetrazine-Norbornene Cycloaddition

    Hee Sun Han;Neal K. Devaraj;Jungmin Lee;Scott A. Hilderbrand

  • Reactive polymer enables efficient in vivo bioorthogonal chemistry

    Neal K. Devaraj;Greg M. Thurber;Edmund J. Keliher;Brett Marinelli

  • Selective Functionalization of Independently Addressed Microelectrodes by Electrochemical Activation and Deactivation of a Coupling Catalyst

    Neal K. Devaraj;Peter H. Dinolfo;Christopher E. D. Chidsey;James P. Collman

  • Communication and quorum sensing in non-living mimics of eukaryotic cells

    Henrike Niederholtmeyer;Cynthia Chaggan;Neal K. Devaraj

  • A Bioorthogonal Near-Infrared Fluorogenic Probe for mRNA Detection

    Haoxing Wu;Seth C. Alexander;Shuaijiang Jin;Neal K. Devaraj

Frequent Co-Authors

Ralph Weissleder
Ralph Weissleder Harvard University
Jun Yang
Jun Yang Shanghai Jiao Tong University
James P. Collman
James P. Collman Stanford University
Christopher E. D. Chidsey
Christopher E. D. Chidsey Stanford University
Don W. Cleveland
Don W. Cleveland University of California, San Diego
Kendall N. Houk
Kendall N. Houk University of California, Los Angeles
Christian M. Metallo
Christian M. Metallo University of California, San Diego
Steven F. Dowdy
Steven F. Dowdy University of California, San Diego
William C. Mobley
William C. Mobley University of California, San Diego

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