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Medicine

D-Index
134
Citations
92218
World Ranking
2103
National Ranking
25

Overview

Matti Uusitupa is affiliated with the University of Eastern Finland in Finland and has a research profile focused on medicine and biochemistry, genetics and molecular biology. Their work spans multiple subfields including physiology, endocrinology, diabetes and metabolism, public health, environmental and occupational health, nutrition and dietetics, and cardiology and cardiovascular medicine.

Their recent papers highlight research on diet, metabolism, and chronic disease prevention. Key publications include:

  • Vitamin D supplementation and prevention of cardiovascular disease and cancer in the Finnish Vitamin D Trial: a randomized controlled trial (2021) published in the American Journal of Clinical Nutrition
  • Combination of Multiple Low-Risk Lifestyle Behaviors and Incident Type 2 Diabetes: A Systematic Review and Dose-Response Meta-analysis of Prospective Cohort Studies (2023) published in Diabetes Care
  • n-3 Fatty Acid Biomarkers and Incident Type 2 Diabetes: An Individual Participant-Level Pooling Project of 20 Prospective Cohort Studies (2021) published in Diabetes Care
  • Association of omega 3 polyunsaturated fatty acids with incident chronic kidney disease: pooled analysis of 19 cohorts (2023) published in BMJ
  • Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake (2023) published in Nature Genetics

The scientist collaborates frequently with several researchers, including Jaana Lindström, Jaakko Tuomilehto, Jyrki K. Virtanen, Vanessa D. de Mello, and Ulf Risérus.

Matti Uusitupa's publication record includes multiple works in prominent journals such as Nutrients, Diabetologia, American Journal of Clinical Nutrition, Diabetes Care, and The Journal of Clinical Endocrinology & Metabolism. Their most frequent publication venues are:

  • Nutrients
  • Diabetologia
  • American Journal of Clinical Nutrition
  • Diabetes Care
  • The Journal of Clinical Endocrinology & Metabolism

The main topics explored in their research encompass diet and metabolism studies, fatty acid research and health, nutritional studies and diet, eicosanoids and hypertension pharmacology, vitamin D research studies, obesity, physical activity and diet, as well as metabolomics and mass spectrometry studies. These areas reflect a broad interest in how nutrition and biochemistry impact metabolic health and chronic disease mechanisms.

Best Publications

  • Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance.

    Tuomilehto J;Lindström J;Eriksson Jg;Valle Tt

  • Discovery and refinement of loci associated with lipid levels

    Cristen J. Willer;Ellen M. Schmidt;Sebanti Sengupta;Gina M. Peloso;Gina M. Peloso;Gina M. Peloso

  • Sustained reduction in the incidence of type 2 diabetes by lifestyle intervention: follow-up of the Finnish Diabetes Prevention Study

    Jaana Lindström;Pirjo Ilanne-Parikka;Markku Peltonen;Sirkka Aunola

  • Defining the role of common variation in the genomic and biological architecture of adult human height

    Andrew R. Wood;Tonu Esko;Jian Yang;Sailaja Vedantam

  • The Finnish Diabetes Prevention Study (DPS) Lifestyle intervention and 3-year results on diet and physical activity

    Jaana Lindström;Anne Louheranta;Marjo Mannelin;Merja Rastas

  • Genetic studies of body mass index yield new insights for obesity biology

    Adam E. Locke;Bratati Kahali;Sonja I. Berndt;Anne E. Justice

  • Substituting dietary saturated for monounsaturated fat impairs insulin sensitivity in healthy men and women: The KANWU Study.

    Bengt Vessby;Matti Uusitupa;Kjeld Hermansen;Gabriele Riccardi

  • Diabetes and atherosclerosis: an epidemiologic view.

    Kalevi Pyörälä;Markku Laakso;Matti Uusitupa

  • Common variants associated with plasma triglycerides and risk for coronary artery disease

    Ron Do;Cristen J. Willer;Ellen M. Schmidt;Sebanti Sengupta

  • A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.

    Alisa K. Manning;Alisa K. Manning;Alisa K. Manning;Robert A. Scott;Jonna L. Grimsby

  • Natural history of peripheral neuropathy in patients with non-insulin-dependent diabetes mellitus.

    Juhani Partanen;Leo Niskanen;Juha Lehtinen;Esa Mervaala

  • Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

    Robert A Scott;Vasiliki Lagou;Ryan P Welch;Eleanor Wheeler

  • Physical Activity in the Prevention of Type 2 Diabetes The Finnish Diabetes Prevention Study

    David E. Laaksonen;Jaana Lindström;Timo A. Lakka;Johan G. Eriksson

  • Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

    Sonja I Berndt;Stefan Gustafsson;Stefan Gustafsson;Reedik Mägi;Reedik Mägi;Andrea Ganna

  • The prevalence of metabolic syndrome and metabolically healthy obesity in Europe: a collaborative analysis of ten large cohort studies.

    Jana V van Vliet-Ostaptchouk;Marja-Liisa Nuotio;Marja-Liisa Nuotio;Sandra N Slagter;Dany Doiron

  • Physical activity attenuates the influence of FTO variants on obesity risk: A meta-analysis of 218,166 adults and 19,268 children

    Tuomas O. Kilpeläinen;Lu Qi;Soren Brage;Stephen J. Sharp

  • The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

    Thomas W. Winkler;Anne E. Justice;Mariaelisa Graff;Llilda Barata

  • Evidence-based nutritional approaches to the treatment and prevention of diabetes mellitus

    J.I. Mann;I. De Leeuw;K. Hermansen;B. Karamanos

  • Ten-year cardiovascular mortality in relation to risk factors and abnormalities in lipoprotein composition in Type 2 (non-insulin-dependent) diabetic and non-diabetic subjects

    M. I. J. Uusitupa;L. K. Niskanen;O. Siitonen;E. Voutilainen

  • Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

    Sonja I. Berndt;Stefan Gustafsson;Reedik Maegi;Andrea Ganna

Frequent Co-Authors

Jaakko Tuomilehto
Jaakko Tuomilehto University of Helsinki
Markku Laakso
Markku Laakso University of Eastern Finland
Leo Niskanen
Leo Niskanen University of Helsinki
Sirkka Keinänen-Kiukaanniemi
Sirkka Keinänen-Kiukaanniemi Oulu University Hospital
Johan G. Eriksson
Johan G. Eriksson National University of Singapore
Kaisa Poutanen
Kaisa Poutanen VTT Technical Research Centre of Finland
Kalevi Pyörälä
Kalevi Pyörälä University of Eastern Finland
Markku Peltonen
Markku Peltonen Finnish Institute for Health and Welfare (THL)
Rainer Rauramaa
Rainer Rauramaa University of Eastern Finland
Helena Gylling
Helena Gylling University of Helsinki

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