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Medicine

D-Index
95
Citations
40563
World Ranking
9943
National Ranking
962

Overview

Martin O. Leach is affiliated with the Royal Marsden NHS Foundation Trust in the United Kingdom, with a research focus predominantly in the field of Medicine. Their work primarily intersects Radiology, Nuclear Medicine and Imaging, supplemented by contributions in Cancer Research, Genetics, Molecular Biology, and Immunology.

Their research topics highlight a concentration on MRI applications in oncology and related technological advances. Main topics addressed in their work include:

  • MRI in cancer diagnosis
  • Radiomics and Machine Learning in Medical Imaging
  • Advanced MRI Techniques and Applications
  • Cancer, Hypoxia, and Metabolism
  • Medical Imaging Techniques and Applications
  • Immune cells in cancer
  • Adipose Tissue and Metabolism

Leach has multiple recent publications across distinct but related biomedical fields. These include:

  • "Monocarboxylate transporter 1 blockade with AZD3965 inhibits lipid biosynthesis and increases tumour immune cell infiltration," 2020, British Journal of Cancer
  • "Noise-Corrected, Exponentially Weighted, Diffusion-Weighted MRI (niceDWI) Improves Image Signal Uniformity in Whole-Body Imaging of Metastatic Prostate Cancer," 2020, Frontiers in Oncology
  • "Development of machine learning support for reading whole body diffusion-weighted MRI (WB-MRI) in myeloma for the detection and quantification of the extent of disease before and after treatment (MALIMAR): protocol for a cross-sectional diagnostic test accuracy study," 2022, BMJ Open
  • "MRI texture feature repeatability and image acquisition factor robustness, a phantom study and in silico study," 2021, European Radiology Experimental
  • "Bevacizumab, Irinotecan, or Topotecan Added to Temozolomide for Children With Relapsed and Refractory Neuroblastoma: Results of the ITCC-SIOPEN BEACON-Neuroblastoma Trial," 2024, Journal of Clinical Oncology

Their work has been published in several key venues, including:

  • European Radiology Experimental
  • British Journal of Cancer
  • Frontiers in Oncology
  • BMJ Open
  • Journal of Clinical Oncology

Frequent collaborators include Dow-Mu Koh, David J. Collins, Matthew Blackledge, Nina Tunariu, and Matthew Orton. These coauthors have worked with Leach on multiple publications, reflecting ongoing collaborative efforts in related research areas.

Best Publications

  • Nonrigid registration using free-form deformations: application to breast MR images

    D. Rueckert;L.I. Sonoda;C. Hayes;D.L.G. Hill

  • American Cancer Society Guidelines for Breast Screening with MRI as an Adjunct to Mammography

    Debbie Saslow;Carla Boetes;Wylie Burke;Steven Harms

  • Screening with magnetic resonance imaging and mammography of a UK population at high familial risk of breast cancer: a prospective multicentre cohort study (MARIBS).

    M O Leach;C R M Boggis;A K Dixon;D F Easton

  • Imaging biomarker roadmap for cancer studies.

    James P.B. O'Connor;Eric O. Aboagye;Judith E. Adams;Hugo J.W.L. Aerts;Hugo J.W.L. Aerts

  • Analysis of Cancer Metabolism by Imaging Hyperpolarized Nuclei: Prospects for Translation to Clinical Research

    John Kurhanewicz;Daniel B. Vigneron;Kevin Brindle;Eduard Y. Chekmenev

  • Clinical Proton MR Spectroscopy in Central Nervous System Disorders

    Gülin Öz;Jeffry R. Alger;Peter B. Barker;Robert Bartha

  • The assessment of antiangiogenic and antivascular therapies in early-stage clinical trials using magnetic resonance imaging: issues and recommendations

    Martin O Leach;K Brindle;J Evelhoch;John R Griffiths

  • Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer.

    Suzanne A. Eccles;Eric O. Aboagye;Simak Ali;Annie S. Anderson

  • Methodological consensus on clinical proton MRS of the brain: Review and recommendations

    Martin Wilson;Ovidiu Andronesi;Peter B Barker;Robert Bartha

  • Dynamic Contrast Enhanced MRI of Prostate Cancer: Correlation with Morphology and Tumour Stage, Histological Grade and PSA

    Anwar R. Padhani;Connie J. Gapinski;David A. Macvicar;Geoffrey J. Parker

  • Predicting Response of Colorectal Hepatic Metastasis: Value of Pretreatment Apparent Diffusion Coefficients

    Dow-Mu Koh;Erica Scurr;David Collins;Baris Kanber

  • Magnetic resonance imaging (MRI): considerations and applications in radiotherapy treatment planning

    Vincent S. Khoo;David P. Dearnaley;David J. Finnigan;Anwar Padhani

  • Validation of nonrigid image registration using finite-element methods: application to breast MR images

    J.A. Schnabel;C. Tanner;A.D. Castellano-Smith;A. Degenhard

  • Measurement reproducibility of perfusion fraction and pseudodiffusion coefficient derived by intravoxel incoherent motion diffusion-weighted MR imaging in normal liver and metastases

    A. Andreou;D. M. Koh;D. M. Koh;D. J. Collins;D. J. Collins;M. Blackledge

  • Assessing changes in tumour vascular function using dynamic contrast-enhanced magnetic resonance imaging

    Carmel Hayes;Anwar R. Padhani;Martin O. Leach

  • Evaluating the effect of rectal distension and rectal movement on prostate gland position using cine MRI

    Anwar R Padhani;Vincent S Khoo;John Suckling;Janet E Husband

  • Prediction of clinicopathologic response of breast cancer to primary chemotherapy at contrast-enhanced MR imaging: Initial clinical results

    Anwar R. Padhani;Carmel Hayes;Laura Assersohn;Trevor Powles

  • A complete distortion correction for MR images: I. Gradient warp correction

    Simon J Doran;Liz Charles-Edwards;Stefan A Reinsberg;Martin O Leach

  • Measurement of the extracellular pH of solid tumours in mice by magnetic resonance spectroscopy: a comparison of exogenous 19F and 31P probes

    Agatha S. E. Ojugo;Paul M. J. McSheehy;Dominick J. O. McIntyre;Cheryl McCoy

  • Screening with magnetic resonance imaging and mammography of a UK population at high familial risk of breast cancer; a prospective multicentre cohort study (MARIBS)

    MO Leach;CR Boggis;AK Dixon;DF Easton

Frequent Co-Authors

David J. Hawkes
David J. Hawkes University College London
Anwar R. Padhani
Anwar R. Padhani Northwood University
Paul Workman
Paul Workman Institute of Cancer Research
John R. Griffiths
John R. Griffiths University of Manchester
Ian Judson
Ian Judson Institute of Cancer Research
David Atkinson
David Atkinson University of Liverpool
Rosalind A. Eeles
Rosalind A. Eeles Institute of Cancer Research
Fiona J. Gilbert
Fiona J. Gilbert University of Cambridge
Angelo Bifone
Angelo Bifone University of Turin
Derek L. G. Hill
Derek L. G. Hill Panoramic Digital Health

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