World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
45
Citations
7576
World Ranking
19119
National Ranking
7809

Overview

Martin J. Hessner is affiliated with the Medical College of Wisconsin in the United States. Their research spans multiple fields within medicine and biochemistry, with a focus on genetics, immunology, molecular biology, and pulmonary and respiratory medicine.

The scientist's principal research topics include:

  • Diabetes and associated disorders
  • Hemoglobinopathies and related disorders
  • Epigenetics and DNA Methylation
  • Gut microbiota and health
  • Pancreatic function and diabetes
  • Neonatal respiratory health research
  • Immune cell function and interaction

Frequently publishing in journals related to hematology, immunology, and clinical research, Hessner has multiple papers in the following venues:

  • Blood
  • Scientific Reports
  • JCI Insight
  • Journal of Pain
  • Journal of the Endocrine Society

Selected recent papers authored or co-authored by Hessner include:

  • Lactobacillus plantarum 299v probiotic supplementation in men with stable coronary artery disease suppresses systemic inflammation, 2021, Scientific Reports
  • Probiotic normalization of systemic inflammation in siblings of type 1 diabetes patients: an open-label pilot study, 2022, Scientific Reports
  • Lipid mediators and biomarkers associated with type 1 diabetes development, 2020, JCI Insight
  • CD4+CD25+CD127hi cell frequency predicts disease progression in type 1 diabetes, 2020, JCI Insight
  • Role of endoplasmic reticulum stress in impaired neonatal lung growth and bronchopulmonary dysplasia, 2022, PLoS ONE

Hessner collaborates frequently with several co-authors, including:

  • Shuang Jia
  • Mark F. Roethle
  • Lana Mucalo
  • Amanda M. Brandow
  • Ashima Singh

Their work relates closely to investigating immune cell functions, genetic factors in diabetes, and the role of gut microbiota in systemic inflammation. Several studies focus on type 1 diabetes and its markers, alongside neonatal respiratory health and related pulmonary conditions.

Overall, Martin J. Hessner's research contributes to understanding complex interactions between genetics, immunology, and metabolic diseases, positioned within clinical and biological contexts.

Best Publications

  • Making a definitive diagnosis: successful clinical application of whole exome sequencing in a child with intractable inflammatory bowel disease.

    Elizabeth A Worthey;Alan N Mayer;Alan N Mayer;Grant D Syverson;Daniel Helbling

  • A requisite role for induced regulatory T cells in tolerance based on expanding antigen receptor diversity.

    Dipica Haribhai;Jason B. Williams;Shuang Jia;Derek Nickerson

  • An autoinflammatory disease due to homozygous deletion of the IL1RN locus.

    Sreelatha Reddy;Shuang Jia;Rhonda Geoffrey;Rachel Lorier

  • Blockade of interleukin-6 signaling augments regulatory T-cell reconstitution and attenuates the severity of graft-versus-host disease.

    Xiao Chen;Rupali Das;Richard Komorowski;Amy Beres

  • Introducing the Endotype Concept to Address the Challenge of Disease Heterogeneity in Type 1 Diabetes.

    Manuela Battaglia;Simi Ahmed;Mark S. Anderson;Mark A. Atkinson

  • Rapid determination of platelet alloantigen genotypes by polymerase chain reaction using allele-specific primers

    Skogen B;Bellissimo Db;Hessner Mj;Santoso S

  • Mast cell activation and neutrophil recruitment promotes early and robust inflammation in the meninges in EAE

    Alison L. Christy;Margaret E. Walker;Martin J. Hessner;Melissa A. Brown

  • Prevalence of Prothrombin G20210A, Factor V G1691A (Leiden), and Methylenetetrahydrofolate Reductase (MTHFR) C677T in Seven Different Populations Determined by Multiplex Allele-specific PCR

    Martin J. Hessner;Robert A. Luhm;Steven L. Pearson;Debra J. Endean

  • Blood group A and B antigens are strongly expressed on platelets of some individuals.

    Brian R. Curtis;Jennifer T. Edwards;Martin J. Hessner;John P. Klein

  • Identification of a Molecular Signature in Human Type 1 Diabetes Mellitus Using Serum and Functional Genomics

    Xujing Wang;Xujing Wang;Shuang Jia;Rhonda Geoffrey;Ramin Alemzadeh

  • T-cell depletion plus salvage immunotherapy with donor leukocyte infusions as a strategy to treat chronic-phase chronic myelogenous leukemia patients undergoing HLA-identical sibling marrow transplantation.

    William R. Drobyski;William R. Drobyski;Martin J. Hessner;Martin J. Hessner;John P. Klein;John P. Klein;Claudia Kabler-Babbitt;Claudia Kabler-Babbitt

  • Activated protein C targets CD8+ dendritic cells to reduce the mortality of endotoxemia in mice

    Edward Kerschen;Irene Hernandez;Mark Zogg;Shuang Jia

  • Determination of neutrophil antigen gene frequencies in five ethnic groups by polymerase chain reaction with sequence‐specific primers

    M J Hessner;B R Curtis;D J Endean;R H Aster

  • Apoptosis of CD4+CD25high T Cells in Type 1 Diabetes May Be Partially Mediated by IL-2 Deprivation

    Parthav Jailwala;Jill Waukau;Sanja Glisic;Srikanta Jana

  • Interleukin-23 secretion by donor antigen-presenting cells is critical for organ-specific pathology in graft-versus-host disease

    Rupali Das;Xiao Chen;Richard Komorowski;Martin J. Hessner

  • Quantitative quality control in microarray experiments and the application in data filtering, normalization and false positive rate prediction.

    Xujing Wang;Martin J. Hessner;Yan Wu;Nirupma Pati

  • IL-10 Produced by Induced Regulatory T Cells (iTregs) Controls Colitis and Pathogenic Ex-iTregs during Immunotherapy

    Erica G. Schmitt;Dipica Haribhai;Jason B. Williams;Praful Aggarwal

  • Evidence of a functional role for mast cells in the development of type 1 diabetes mellitus in the BioBreeding rat.

    Rhonda Geoffrey;Shuang Jia;Anne E Kwitek;Jeffrey Woodliff

  • Innate inflammation in type 1 diabetes

    Susanne M. Cabrera;Susanne M. Cabrera;Angela M. Henschel;Angela M. Henschel;Martin J. Hessner;Martin J. Hessner

  • Impaired survival of peripheral T cells, disrupted NK/NKT cell development, and liver failure in mice lacking Gimap5

    Ryan D. Schulteis;Haiyan Chu;Xuezhi Dai;Yuhong Chen

Frequent Co-Authors

Guo-Cheng Yuan
Guo-Cheng Yuan Icahn School of Medicine at Mount Sinai
William R. Drobyski
William R. Drobyski Medical College of Wisconsin
Pippa Simpson
Pippa Simpson Medical College of Wisconsin
Åke Lernmark
Åke Lernmark Lund University
Ulrich Broeckel
Ulrich Broeckel Medical College of Wisconsin
Howard J. Jacob
Howard J. Jacob AbbVie (United States)
Anne E. Kwitek
Anne E. Kwitek Medical College of Wisconsin
Noel G. Morgan
Noel G. Morgan University of Exeter
Richard H. Aster
Richard H. Aster Medical College of Wisconsin
Carla J. Greenbaum
Carla J. Greenbaum Virginia Mason Medical Center

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Biology and Biochemistry can lead to a range of exciting online degree opportunities. For those interested in healthcare administration, pursuing cahme accreditation mha programs ensures strong management training recognized by employers. These accredited programs can open doors to high-level administrative roles in hospitals and clinics.

If you're interested in advanced nursing leadership but need a flexible path, you might consider dnp online no clinicals programs. These allow students to earn a Doctor of Nursing Practice without required in-person clinical hours—ideal for working professionals aiming for executive or academic roles.

For those who see themselves in research, policy, or higher management, a phd in healthcare management can provide deep analytical and strategic skills for the healthcare sector. Alternatively, if pharmacy is your direction, an online pharmd offers accredited pharmaceutical training for those wanting licensed pharmacist careers.

Each degree pathway connects closely with the foundational knowledge from studying Biology and Biochemistry, preparing graduates for leadership in modern healthcare and scientific industries.

Best Scientists Citing Martin J. Hessner

Trending Scientists

Recently Published Articles