Marcus Groettrup

Best Publications

• Efficient presentation of exogenous antigen by liver endothelial cells to CD8+ T cells results in antigen-specific T-cell tolerance.

  Andreas Limmer;Jutta Ohl;Christian Kurts;Hans-Gustaf Ljunggren

  880
  Citations

• Prostaglandin E2 is a key factor for CCR7 surface expression and migration of monocyte-derived dendritic cells.

  Elke Scandella;Ying Men;Silke Gillessen;Reinhold Förster

  660
  Citations

• Analysis and expression of a cloned pre-T cell receptor gene.

  C Saint-Ruf;K Ungewiss;M Groettrup;L Bruno

  543
  Citations

• A role for the proteasome regulator PA28α in antigen presentation

  Marcus Groettrup;Andrea Soza;Maren Eggers;Lothar Kuehn

  460
  Citations

• A novel disulfide-linked heterodimer on pre—T cells consists of the T cell receptor β chain and a 33 kd glycoprotein

  Marcus Groettrup;Katharina Ungewiss;Orly Azogui;Ronald Palacios

  439
  Citations

• Proteasomes in immune cells: more than peptide producers?

  Marcus Groettrup;Christopher J. Kirk;Michael Basler

  419
  Citations

• Coordinated Dual Cleavages Induced by the Proteasome Regulator PA28 Lead to Dominant MHC Ligands

  Tobias P. Dick;Thomas Ruppert;Marcus Groettrup;Peter M. Kloetzel

  372
  Citations

• TLR ligands and antigen need to be coencapsulated into the same biodegradable microsphere for the generation of potent cytotoxic T lymphocyte responses

  Eva Schlosser;Marc Mueller;Stefan Fischer;Sameh Basta

  354
  Citations

• An inhibitor of HIV-1 protease modulates proteasome activity, antigen presentation, and T cell responses.

  P André;M Groettrup;P Klenerman;R de Giuli

  350
  Citations

• CCL19/CCL21-triggered signal transduction and migration of dendritic cells requires prostaglandin E2

  Elke Scandella;Ying Men;Daniel F Legler;Silke Gillessen

  294
  Citations

• Peptide antigen production by the proteasome: complexity provides efficiency

  Marcus Groettrup;Andrea Soza;Ulrike Kuckelkorn;Peter-M. Kloetzel

  290
  Citations

• PLGA microspheres for improved antigen delivery to dendritic cells as cellular vaccines.

  Ying Waeckerle-Men;Marcus Groettrup

  270
  Citations

• The subunits MECL-1 and LMP2 are mutually required for incorporation into the 20S proteasome.

  Unknown

  249
  Citations

• Prostaglandin E2 Is Generally Required for Human Dendritic Cell Migration and Exerts Its Effect via EP2 and EP4 Receptors

  Daniel F. Legler;Petra Krause;Elke Scandella;Eva Singer

  248
  Citations

• Incorporation of major histocompatibility complex--encoded subunits LMP2 and LMP7 changes the quality of the 20S proteasome polypeptide processing products independent of interferon-gamma.

  Ulrike Kuckelkorn;Stefan Frentzel;Regine Kraft;Susanne Kostka

  242
  Citations

• Dendritic cells up-regulate immunoproteasomes and the proteasome regulator PA28 during maturation.

  Annalisa Macagno;Michel Gilliet;Federica Sallusto;Antonio Lanzavecchia

  241
  Citations

• How an Inhibitor of the HIV-I Protease Modulates Proteasome Activity

  Gunter Schmidtke;Hermann-Georg Holzhütter;Matthew Bogyo;Norman Kairies

  233
  Citations

• Immunoproteasomes Largely Replace Constitutive Proteasomes During an Antiviral and Antibacterial Immune Response in the Liver

  Selina Khan;Maries van den Broek;Katrin Schwarz;Rita de Giuli

  229
  Citations

• A Single Residue Exchange Within a Viral CTL Epitope Alters Proteasome-Mediated Degradation Resulting in Lack of Antigen Presentation

  Ferry Ossendorp;Maren Eggers;Anne Neisig;Thomas Ruppert

  225
  Citations

• Prostate stem cell antigen is a promising candidate for immunotherapy of advanced prostate cancer.

  Jens Dannull;Pierre-André Diener;Ladislav Prikler;Gregor Fürstenberger

  223
  Citations