World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
91
Citations
32605
World Ranking
644
National Ranking
298

Medicine

D-Index
91
Citations
32589
World Ranking
11699
National Ranking
6002

Research.com Recognitions

  • 2010 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Malcolm A. Martin is affiliated with the National Institutes of Health in the United States. Their research primarily focuses on immunology and microbiology, with significant contributions in medicine. Within these broader fields, their work spans subfields including immunology, virology, infectious diseases, epidemiology, and molecular biology.

The central themes of their research involve HIV research and treatment, immune cell function and interaction, T-cell and B-cell immunology, as well as HIV/AIDS drug development and treatment. Additionally, they have contributed to studies on herpesvirus infections and treatments, cytomegalovirus and herpesvirus research, and monoclonal and polyclonal antibodies research.

Malcolm A. Martin has published extensively, with notable papers including:

  • Sequential immunization of macaques elicits heterologous neutralizing antibodies targeting the V3-glycan patch of HIV-1 Env (2021, Science Translational Medicine)
  • Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer (2022, Nature Communications)
  • CD4 binding site immunogens elicit heterologous anti-HIV-1 neutralizing antibodies in transgenic and wild-type animals (2023, Science Immunology)
  • A broadly neutralizing macaque monoclonal antibody against the HIV-1 V3-Glycan patch (2020, eLife)
  • Induction of durable remission by dual immunotherapy in SHIV-infected ART-suppressed macaques (2024, Science)

Their work has appeared frequently in publication venues such as bioRxiv (Cold Spring Harbor Laboratory), with six publications, alongside single contributions to Science Translational Medicine, Science Immunology, Nature Communications, and Science.

Frequent collaborators include Michel C. Nussenzweig, Harry B. Gristick, Yoshiaki Nishimura, Pamela J. Björkman, and Anthony P. West.

Recognition of their scientific contributions includes the distinction of Fellow of the American Association for the Advancement of Science (AAAS), awarded in 2010.

Best Publications

  • Detection of AIDS virus in macrophages in brain tissue from AIDS patients with encephalopathy.

    Scott Koenig;Howard E. Gendelman;Jan M. Orenstein;Mauro Carlo Dal Canto

  • Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection.

    Joseph J. Mattapallil;Daniel C. Douek;Brenna Hill;Yoshiaki Nishimura

  • Human immunodeficiency virus type 1 Vpu protein induces rapid degradation of CD4.

    R L Willey;F Maldarelli;M A Martin;K Strebel

  • Alternative splicing of human immunodeficiency virus type 1 mRNA modulates viral protein expression, replication, and infectivity.

    Damian F. J. Purcell;Malcolm A. Martin

  • Neutralizing antibody directed against the HIV-1 envelope glycoprotein can completely block HIV-1/SIV chimeric virus infections of macaque monkeys.

    Riri Shibata;Tatsuhiko Igarashi;Nancy Haigwood;Alicia Buckler-White

  • The HIV 'A' (sor) gene product is essential for virus infectivity.

    Klaus Strebel;Daryl Daugherty;Kathleen Clouse;David Cohen

  • The human immunodeficiency virus type 1-specific protein vpu is required for efficient virus maturation and release.

    T Klimkait;K Strebel;M D Hoggan;M A Martin

  • p6Gag is required for particle production from full-length human immunodeficiency virus type 1 molecular clones expressing protease.

    Mingjun Huang;J. M. Orenstein;M. A. Martin;E. O. Freed

  • A novel gene of HIV-1, vpu, and its 16-kilodalton product.

    Klaus Strebel;Thomas Klimkait;Malcolm A. Martin

  • Quantitation of human immunodeficiency virus type 1 infection kinetics.

    D. S. Dimitrov;R. L. Willey;H. Sato;Lung-Ji Chang

  • Administration of an Anti-CD8 Monoclonal Antibody Interferes with the Clearance of Chimeric Simian/Human Immunodeficiency Virus during Primary Infections of Rhesus Macaques

    T Matano;R Shibata;C Siemon;M Connors

  • Antibody-mediated immunotherapy of macaques chronically infected with SHIV suppresses viraemia

    Masashi Shingai;Yoshiaki Nishimura;Florian Klein;Hugo Mouquet

  • Biosynthesis, cleavage, and degradation of the human immunodeficiency virus 1 envelope glycoprotein gp160.

    Ronald L. Willey;Juan S. Bonifacino;Barbara J. Potts;Malcolm A. Martin

  • Multiple effects of mutations in human immunodeficiency virus type 1 integrase on viral replication.

    A Engelman;G Englund;J M Orenstein;M A Martin

  • Macrophage are the principal reservoir and sustain high virus loads in rhesus macaques after the depletion of CD4+ T cells by a highly pathogenic simian immunodeficiency virus/HIV type 1 chimera (SHIV): Implications for HIV-1 infections of humans

    Tatsuhiko Igarashi;Charles R. Brown;Yasuyuki Endo;Alicia Buckler-White

  • Biological and biochemical characterization of a cloned leu-3− cell surviving infection with the acquired immune deficiency syndrome retrovirus

    T. M. Folks;D. Powell;M. Lightfoote;S. Koenig

  • Trans-activation of the human immunodeficiency virus long terminal repeat sequence by DNA viruses.

    Howard E. Gendelman;William Phelps;Lionel Feigenbaum;Jeffrey M. Ostrove

  • Characterization of a continuous T-cell line susceptible to the cytopathic effects of the acquired immunodeficiency syndrome (AIDS)-associated retrovirus

    T. Folks;S. Benn;A. Rabson;T. Theodore

  • DOMAINS OF THE HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 MATRIX AND GP41 CYTOPLASMIC TAIL REQUIRED FOR ENVELOPE INCORPORATION INTO VIRIONS

    E O Freed;M A Martin

  • Virion incorporation of envelope glycoproteins with long but not short cytoplasmic tails is blocked by specific, single amino acid substitutions in the human immunodeficiency virus type 1 matrix.

    E O Freed;M A Martin

  • A rapid method for detecting and mapping homology between heterologous DNAs. Evaluation of polyomavirus genomes.

    P.M. Howley;M.A. Israel;M.F. Law;M.A. Martin

Frequent Co-Authors

Alicia Buckler-White
Alicia Buckler-White National Institutes of Health
Michel C. Nussenzweig
Michel C. Nussenzweig Rockefeller University
George Khoury
George Khoury National Institutes of Health
Peter M. Howley
Peter M. Howley Harvard Medical School
Wallace P. Rowe
Wallace P. Rowe National Institutes of Health
Michael S. Seaman
Michael S. Seaman Beth Israel Deaconess Medical Center
Klaus Strebel
Klaus Strebel National Institutes of Health
Anna Gazumyan
Anna Gazumyan Rockefeller University
Dimiter S. Dimitrov
Dimiter S. Dimitrov University of Pittsburgh
Pamela J. Bjorkman
Pamela J. Bjorkman California Institute of Technology

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For students interested in the broad field of microbiology, exploring related online degrees can open up diverse career options. One accessible pathway is through fast online medical billing and coding certification programs. These programs offer a quick route into healthcare administration, supporting clinical settings where microbiological data plays a crucial role.

Additionally, many universities now offer what medical degrees can I get online, making it easier to pursue careers related to infectious diseases, immunology, and public health without compromising flexibility.

For those interested in public health, there are accredited online MPH programs easy to get into that provide a strong foundation in epidemiology and disease control, both critical areas connected to microbiological research and practice.

Beyond traditional paths, roles such as a child life specialist allow professionals to support pediatric patients, including those impacted by microbial infections, by aiding their emotional well-being during treatment.

Best Scientists Citing Malcolm A. Martin

Trending Scientists

Recently Published Articles