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Biology and Biochemistry

D-Index
97
Citations
67544
World Ranking
1712
National Ranking
954

Overview

Joseph S. Beckman is affiliated with Oregon State University in the United States. Their research spans several interconnected fields, primarily focusing on Medicine, Biochemistry, Genetics and Molecular Biology, and Chemistry. The subfields of their work include Molecular Biology, Neurology, Spectroscopy, Radiology, Nuclear Medicine and Imaging, and Genetics.

The scientist's publication record features multiple recent papers emphasizing advanced methods in protein characterization and neurodegenerative disease mechanisms. Notable papers include:

  • Comparative Structural Analysis of 20S Proteasome Ortholog Protein Complexes by Native Mass Spectrometry, 2020, ACS Central Science
  • Top-Down Characterization of Denatured Proteins and Native Protein Complexes Using Electron Capture Dissociation Implemented within a Modified Ion Mobility-Mass Spectrometer, 2020, Analytical Chemistry
  • Improved Protein and PTM Characterization with a Practical Electron-Based Fragmentation on Q-TOF Instruments, 2021, Journal of the American Society for Mass Spectrometry
  • Genetic Incorporation of Two Mutually Orthogonal Bioorthogonal Amino Acids That Enable Efficient Protein Dual-Labeling in Cells, 2021, ACS Chemical Biology
  • Microglial ferroptotic stress causes non-cell autonomous neuronal death, 2024, Molecular Neurodegeneration

The venues where Joseph S. Beckman frequently publishes include bioRxiv (Cold Spring Harbor Laboratory), the Journal of the American Society for Mass Spectrometry, ACS Central Science, Analytical Chemistry, and ACS Chemical Biology.

The scientist collaborates regularly with several researchers, including Blaine R. Roberts, Rachel Franklin, Peter J. Crouch, Ryan A. Mehl, and Jeffrey R. Liddell.

Joseph S. Beckman's research topics reflect a focus on the molecular mechanisms underlying neurodegenerative and muscular disorders. The main topics covered are:

  • Amyotrophic Lateral Sclerosis Research
  • Mass Spectrometry Techniques and Applications
  • Advanced Proteomics Techniques and Applications
  • Ubiquitin and proteasome pathways
  • Monoclonal and Polyclonal Antibodies Research
  • Parkinson's Disease Mechanisms and Treatments
  • Neurogenetic and Muscular Disorders Research

Best Publications

  • Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.

    Joseph S. Beckman;Tanya W. Beckman;Jun Chen;Patricia A. Marshall

  • Peroxynitrite oxidation of sulfhydryls. The cytotoxic potential of superoxide and nitric oxide.

    R Radi;J S Beckman;K M Bush;B A Freeman

  • Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase

    Harry Ischiropoulos;Ling Zhu;Jun Chen;Michael Tsai

  • Widespread Peroxynitrite-Mediated Damage in Alzheimer’s Disease

    Mark A. Smith;Peggy L. Richey Harris;Lawrence M. Sayre;Joseph S. Beckman

  • Peroxynitrite formation from macrophage-derived nitric oxide

    Harry Ischiropoulos;Ling Zhu;Joseph S. Beckman

  • Oxidative Damage and Tyrosine Nitration from Peroxynitrite

    Joseph S. Beckman

  • ALS, SOD and peroxynitrite

    Joseph S. Beckman;Michael Carson;Craig D. Smith;Willem H. Koppenol

  • Oxidative stress and nitration in neurodegeneration: cause, effect, or association?

    Harry Ischiropoulos;Joseph S. Beckman

  • Pathological implications of nitric oxide, superoxide and peroxynitrite formation

    Joseph S. Beckman;John P. Crow

  • Kinetics of superoxide dismutase- and iron-catalyzed nitration of phenolics by peroxynitrite.

    Joseph S. Beckman;Harry Ischiropoulos;Ling Zhu;Mark van der Woerd

  • Nitration and inactivation of manganese superoxide dismutase in chronic rejection of human renal allografts

    L. A. MacMillan-Crow;John P. Crow;Jeffrey D. Kerby;Joseph S. Beckman

  • Selective fluorescent imaging of superoxide in vivo using ethidium-based probes

    Kristine M. Robinson;Michael S. Janes;Mariana Pehar;Jeffrey S. Monette

  • Induction of Nitric Oxide -- Dependent Apoptosis in Motor Neurons by Zinc-Deficient Superoxide Dismutase

    Alvaro G. Estévez;John P. Crow;Jacinda B. Sampson;Christopher Reiter

  • Quantitation of nitrotyrosine levels in lung sections of patients and animals with acute lung injury.

    I. Y. Haddad;G. Pataki;Ping Hu;C. Galliani

  • Decreased Zinc Affinity of Amyotrophic Lateral Sclerosis-Associated Superoxide Dismutase Mutants Leads to Enhanced Catalysis of Tyrosine Nitration by Peroxynitrite

    John P. Crow;Jacinda B. Sampson;Yingxin Zhuang;John A. Thompson

  • Polyethylene glycol-conjugated superoxide dismutase and catalase reduce ischemic brain injury

    Tsung H. Liu;Joseph S. Beckman;Bruce A. Freeman;Edward L. Hogan

  • Superoxide Reacts with Nitric Oxide to Nitrate Tyrosine at Physiological pH via Peroxynitrite

    Christopher D. Reiter;Ru-Jeng Teng;Joseph S. Beckman

  • Superoxide Dismutase and Catalase Conjugated to Polyethylene Glycol Increases Endothelial Enzyme Activity and Oxidant Resistance

    J S Beckman;R L Minor;C W White;J E Repine

  • Peroxynitrite-induced luminol chemiluminescence

    R Radi;T P Cosgrove;J S Beckman;B A Freeman

  • Role of inducible nitric oxide synthase expression and peroxynitrite formation in guinea pig ileitis

    Mark J.S. Miller;Jane H. Thompson;Xiao-Jing Zhang;Halina Sadowska-Krowicka

Frequent Co-Authors

Rafael Radi
Rafael Radi University of the Republic
Harry Ischiropoulos
Harry Ischiropoulos Children's Hospital of Philadelphia
Ivan C. Moura
Ivan C. Moura Inserm : Institut national de la santé et de la recherche médicale
Anthony R. White
Anthony R. White QIMR Berghofer Medical Research Institute
Olivier Hermine
Olivier Hermine Necker-Enfants Malades Hospital
Sadis Matalon
Sadis Matalon University of Alabama at Birmingham
Max L. Deinzer
Max L. Deinzer Oregon State University
Ashley I. Bush
Ashley I. Bush Florey Institute of Neuroscience and Mental Health
Tory M. Hagen
Tory M. Hagen Oregon State University

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