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John R. McLaughlin

John R. McLaughlin

D-Index & Metrics

Medicine

D-Index
87
Citations
32222
World Ranking
13530
National Ranking
554

Overview

John R. McLaughlin is affiliated with the University of Toronto in Canada. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Within these fields, their subfields of focus include Public Health, Environmental and Occupational Health, Genetics, Health, Toxicology and Mutagenesis, Oncology, and Molecular Biology.

The scientist has contributed to research on several key topics, including:

  • Carcinogens and Genotoxicity Assessment
  • Colorectal Cancer Screening and Detection
  • Air Quality and Health Impacts
  • Autism Spectrum Disorder Research
  • Inflammatory Bowel Disease
  • Genetics and Neurodevelopmental Disorders
  • RNA Research and Splicing

Recent publications by John R. McLaughlin cover a range of biomedical and public health topics, published in different venues. Selected papers include:

  • Cell-Selective Adeno-Associated Virus-Mediated SCN1A Gene Regulation Therapy Rescues Mortality and Seizure Phenotypes in a Dravet Syndrome Mouse Model and Is Well Tolerated in Nonhuman Primates, 2022, Human Gene Therapy
  • Occupational exposure to nickel and hexavalent chromium and the risk of lung cancer in a pooled analysis of case-control studies (SYNERGY), 2022, International Journal of Cancer
  • Occupational Exposure to Polycyclic Aromatic Hydrocarbons and Lung Cancer Risk: Results from a Pooled Analysis of Case-Control Studies (SYNERGY), 2022, Cancer Epidemiology Biomarkers & Prevention
  • Long-term exposure to air pollution and mortality in a prospective cohort: The Ontario Health Study, 2021, Environment International
  • Identifying Children and Youth With Autism Spectrum Disorder in Electronic Medical Records: Examining Health System Utilization and Comorbidities, 2020, Autism Research

John R. McLaughlin frequently publishes in venues such as:

  • International Journal of Cancer
  • Autism Research
  • British Journal of Cancer
  • Human Gene Therapy
  • Cancer Epidemiology Biomarkers & Prevention

Their frequent coauthors include Paul A. Demers, Rayjean J. Hung, Sierra Cheng, M. Catherine Brown, and James T. Rutka. These collaborations have contributed to multiple publications, indicating ongoing research partnerships across related disciplines.

Best Publications

  • Strengthening the reporting of genetic association studies (STREGA): an extension of the STROBE statement

    Julian Little;Julian P.T. Higgins;John P.A. Ioannidis;John P.A. Ioannidis;David Moher

  • A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25

    Rayjean J. Hung;James D. Mckay;Valerie Gaborieau;Paolo Boffetta

  • Prevalence and Penetrance of Germline BRCA1 and BRCA2 Mutations in a Population Series of 649 Women with Ovarian Cancer

    Harvey A. Risch;John R. McLaughlin;David E.C. Cole;Barry Rosen

  • Common Genetic Variation In Cellular Transport Genes and Epithelial Ovarian Cancer (EOC) Risk

    Ganna Chornokur;Hui-Yi Lin;Jonathan P. Tyrer;Kate Lawrenson

  • Population BRCA1 and BRCA2 Mutation Frequencies and Cancer Penetrances: A Kin–Cohort Study in Ontario, Canada

    Harvey A. Risch;John R. McLaughlin;David E. C. Cole;Barry Rosen

  • Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24

    Brent W. Zanke;Celia M.T. Greenwood;Celia M.T. Greenwood;Jagadish Rangrej;Rafal Kustra;Rafal Kustra

  • Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes

    James D McKay;Rayjean J Hung;Younghun Han;Xuchen Zong

  • Lung cancer susceptibility locus at 5p15.33

    James D McKay;Rayjean J Hung;Rayjean J Hung;Valerie Gaborieau;Paolo Boffetta

  • Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

    Stig E. Bojesen;Stig E. Bojesen;Karen A. Pooley;Sharon E. Johnatty;Jonathan Beesley

  • A Genome-wide Association Study of Lung Cancer Identifies a Region of Chromosome 5p15 Associated with Risk for Adenocarcinoma.

    Maria Teresa Landi;Nilanjan Chatterjee;Kai Yu;Lynn R. Goldin

  • Frequencies of BRCA1 and BRCA2 mutations among 1,342 unselected patients with invasive ovarian cancer.

    Shiyu Zhang;Robert Royer;Song Li;John R. McLaughlin

  • Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

    Catherine M Phelan;Karoline B Kuchenbaecker;Karoline B Kuchenbaecker;Jonathan P Tyrer;Siddhartha P Kar

  • Non-Hodgkin’s Lymphoma and Specific Pesticide Exposures in Men: Cross-Canada Study of Pesticides and Health

    Helen H. McDuffie;Punam Pahwa;John R. McLaughlin;John J. Spinelli

  • GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer

    Paul D.P. Pharoah;Ya Yu Tsai;Susan J. Ramus;Catherine M. Phelan

  • Breast cancer mortality between 1950 and 1987 after exposure to fractionated moderate-dose-rate ionizing radiation in the Canadian fluoroscopy cohort study and a comparison with breast cancer mortality in the atomic bomb survivors study

    Geoffrey R. Howe;John McLaughlin

  • A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24

    Ellen L Goode;Georgia Chenevix-Trench;Honglin Song;Susan J Ramus

  • Previous Lung Diseases and Lung Cancer Risk: A Systematic Review and Meta-Analysis

    Darren R. Brenner;Darren R. Brenner;John R. McLaughlin;John R. McLaughlin;John R. McLaughlin;Rayjean J. Hung;Rayjean J. Hung

  • A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2.

    Honglin Song;Susan J. Ramus;Jonathan Tyrer;Kelly L. Bolton;Kelly L. Bolton

  • Non-Hodgkin’s Lymphoma and Specific Pesticide Exposures in Men

    Helen H. McDuffie;Punam Pahwa;John R. McLaughlin;John J. Spinelli

  • STrengthening the REporting of Genetic Association studies (STREGA)

    Julian Little;{Julian P. T} Higgins;{John P. A} Ioannidis;David Moher

Frequent Co-Authors

Steven A. Narod
Steven A. Narod University of Toronto
Jolanta Lissowska
Jolanta Lissowska Maria Sklodowska-Curie National Research Institute of Oncology
Graham G. Giles
Graham G. Giles University of Melbourne
Rayjean J. Hung
Rayjean J. Hung Lunenfeld-Tanenbaum Research Institute
Harvey A. Risch
Harvey A. Risch Yale University
John J. Spinelli
John J. Spinelli University of British Columbia
John K. Field
John K. Field University of Liverpool
Paolo Boffetta
Paolo Boffetta Stony Brook Medicine
Paul Brennan
Paul Brennan International Agency For Research On Cancer
Jenny Chang-Claude
Jenny Chang-Claude German Cancer Research Center

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