World's Best Scientists 2026 revealed!
Jeffrey R. Gulcher

Jeffrey R. Gulcher

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Biology and Biochemistry
Iceland
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
102
Citations
60731
World Ranking
1334
National Ranking
2

Medicine

D-Index
103
Citations
60972
World Ranking
7180
National Ranking
6

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Iceland Leader Award
  • 2025 - Research.com Biology and Biochemistry in Iceland Leader Award
  • 2023 - Research.com Biology and Biochemistry in Iceland Leader Award
  • 2022 - Research.com Biology and Biochemistry in Iceland Leader Award

Overview

Jeffrey R. Gulcher is affiliated with deCODE Genetics in Iceland. Their research spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a particular focus on Molecular Biology, Genetics, and Infectious Diseases. Additional areas of study include Pulmonary and Respiratory Medicine and Artificial Intelligence.

The scientist's main research topics encompass COVID-19 clinical research studies, SARS-CoV-2 and COVID-19 research, aortic aneurysm repair treatments, aortic disease and treatment approaches, connective tissue disorders research, phagocytosis and immune regulation, and PI3K/AKT/mTOR signaling in cancer.

Frequent collaborators include Thomas W. Chittenden, Sharvari Gujja, Michael Simons, Jose Malagon-Lopez, and Daniel A. Lidar.

Jeffrey R. Gulcher has published in a variety of scientific venues. The most frequent publication venues are UNC Libraries and Genetics in Medicine Open, with additional works appearing in Cell Stem Cell, Science Translational Medicine, and Journal of Clinical Investigation.

Selected recent papers include:

  • Smooth Muscle Cell Reprogramming in Aortic Aneurysms, 2020, Cell Stem Cell
  • Identification of Driver Genes for Critical Forms of COVID-19 in a Deeply Phenotyped Young Patient Cohort, 2021, Science Translational Medicine
  • Chronic mTOR Activation Induces a Degradative Smooth Muscle Cell Phenotype, 2020, Journal of Clinical Investigation
  • Quantum Processor-Inspired Machine Learning in the Biomedical Sciences, 2021, Patterns
  • Proteogenomic Characterization of Primary Colorectal Cancer and Metastatic Progression Identifies Proteome-Based Subtypes and Signatures, 2024, Cell Reports

Best Publications

  • Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes.

    Struan F. A. Grant;Gudmar Thorleifsson;Inga Reynisdottir;Rafil Benediktsson

  • Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

    Heribert Schunkert;Inke R. König;Sekar Kathiresan;Muredach P. Reilly

  • Neuregulin 1 and Susceptibility to Schizophrenia

    Hreinn Stefansson;Engilbert Sigurdsson;Valgerdur Steinthorsdottir;Soley Bjornsdottir

  • Large recurrent microdeletions associated with schizophrenia

    Hreinn Stefansson;Dan Rujescu;Sven Cichon;Olli P. H. Pietilainen

  • A high-resolution recombination map of the human genome

    Augustine Kong;Daniel F. Gudbjartsson;Jesus Sainz;Gudrun M. Jonsdottir

  • Common variants conferring risk of schizophrenia

    Hreinn Stefansson;Hreinn Stefansson;Roel A. Ophoff;Roel A. Ophoff;Roel A. Ophoff;Stacy Steinberg;Stacy Steinberg;Ole A. Andreassen

  • A common variant on chromosome 9p21 affects the risk of myocardial infarction

    Anna Helgadottir;Gudmar Thorleifsson;Andrei Manolescu;Solveig Gretarsdottir

  • A variant associated with nicotine dependence, lung cancer and peripheral arterial disease.

    Thorgeir E Thorgeirsson;Frank Geller;Patrick Sulem;Thorunn Rafnar

  • Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity

    Gudmar Thorleifsson;G Bragi Walters;Daniel F Gudbjartsson;Valgerdur Steinthorsdottir

  • Genetics of gene expression and its effect on disease

    Valur Emilsson;Gudmar Thorleifsson;Bin Zhang;Amy S. Leonardson

  • A variant in CDKAL1 influences insulin response and risk of type 2 diabetes.

    Valgerdur Steinthorsdottir;Gudmar Thorleifsson;Inga Reynisdottir;Rafn Benediktsson

  • The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke

    Anna Helgadottir;Andrei Manolescu;Gudmar Thorleifsson;Solveig Gretarsdottir

  • Variants conferring risk of atrial fibrillation on chromosome 4q25

    Daniel F Gudbjartsson;David O Arnar;Anna Helgadottir;Solveig Gretarsdottir

  • Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24.

    Julius Gudmundsson;Patrick Sulem;Andrei Manolescu;Laufey T Amundadottir

  • A common variant associated with prostate cancer in European and African populations

    Laufey T. Amundadottir;Patrick Sulem;Julius Gudmundsson;Agnar Helgason

  • A common inversion under selection in Europeans

    Hreinn Stefansson;Agnar Helgason;Gudmar Thorleifsson;Valgerdur Steinthorsdottir

  • Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor-positive breast cancer.

    Simon N Stacey;Andrei Manolescu;Patrick Sulem;Thorunn Rafnar

  • Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction.

    Daniel F Gudbjartsson;Unnur S Bjornsdottir;Unnur S Bjornsdottir;Eva Halapi;Anna Helgadottir

  • Genetic determinants of hair, eye and skin pigmentation in Europeans.

    Patrick Sulem;Daniel F Gudbjartsson;Simon N Stacey;Agnar Helgason

  • Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes

    Julius Gudmundsson;Patrick Sulem;Valgerdur Steinthorsdottir;Jon T. Bergthorsson

Frequent Co-Authors

Kari Stefansson
Kari Stefansson deCODE Genetics (Iceland)
Augustine Kong
Augustine Kong University of Oxford
Unnur Thorsteinsdottir
Unnur Thorsteinsdottir deCODE Genetics (Iceland)
Daniel F. Gudbjartsson
Daniel F. Gudbjartsson deCODE Genetics (Iceland)
Gudmar Thorleifsson
Gudmar Thorleifsson deCODE Genetics (Iceland)
Hreinn Stefansson
Hreinn Stefansson deCODE Genetics (Iceland)
Michael L. Frigge
Michael L. Frigge deCODE Genetics (Iceland)
Patrick Sulem
Patrick Sulem deCODE Genetics (Iceland)
Agnar Helgason
Agnar Helgason University of Iceland
Hakon Hakonarson
Hakon Hakonarson Children's Hospital of Philadelphia

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