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Biology and Biochemistry

D-Index
41
Citations
6432
World Ranking
19559
National Ranking
588

Overview

Anthony N. Hodder is affiliated with the Walter and Eliza Hall Institute of Medical Research in Australia. Their research primarily focuses on malaria, with significant contributions to the understanding of molecular mechanisms and drug discovery related to Plasmodium species, the parasites responsible for malaria.

Their main fields of study include Medicine and Biochemistry, Genetics and Molecular Biology. Within these domains, their work spans several subfields, such as Public Health, Environmental and Occupational Health, Molecular Biology, Computational Theory and Mathematics, Epidemiology, and Cell Biology.

Key topics covered by their research include:

  • Malaria Research and Control
  • Computational Drug Discovery Methods
  • Trypanosoma species research and implications
  • Mosquito-borne diseases and control
  • Invertebrate Immune Response Mechanisms
  • Antimicrobial Peptides and Activities
  • Traditional and Medicinal Uses of Annonaceae

Selected recent publications involving Anthony N. Hodder include:

  • "Basis for drug selectivity of plasmepsin IX and X inhibition in Plasmodium falciparum and vivax", 2022, published in Structure
  • "Substrate Peptidomimetic Inhibitors of P. falciparum Plasmepsin X with Potent Antimalarial Activity", 2022, published in ChemMedChem
  • "Flp/ FRT -mediated disruption of ptex150 and exp2 in Plasmodium falciparum sporozoites inhibits liver-stage development", 2024, published in Proceedings of the National Academy of Sciences
  • "Structure of the Plasmodium falciparum PfSERA5 pseudo-zymogen", 2020, published in Protein Science
  • "Competitive binding of actin and SH3 domains at proline-rich regions of Las17/WASP regulates actin polymerisation", 2025, published in Communications Biology

Frequent co-authors collaborating with Hodder include:

  • Alan F. Cowman
  • Anna Ngo
  • S.W. Scally
  • Tony Triglia
  • Paola Favuzza

Their work has been published in various venues, reflecting interdisciplinary reach:

  • Structure
  • Proceedings of the National Academy of Sciences
  • ChemMedChem
  • Communications Biology
  • Research Square

Best Publications

  • Specificity of the Protective Antibody Response to Apical Membrane Antigen 1

    Anthony N. Hodder;Pauline E. Crewther;Robin F. Anders

  • Apical membrane antigen 1 plays a central role in erythrocyte invasion by Plasmodium species

    Tony Triglia;Julie Healer;Sonia R. Caruana;Anthony N. Hodder;Anthony N. Hodder

  • An aspartyl protease directs malaria effector proteins to the host cell

    Justin A. Boddey;Anthony N. Hodder;Svenja Günther;Paul R. Gilson

  • THE DISULFIDE BOND STRUCTURE OF PLASMODIUM APICAL MEMBRANE ANTIGEN-1

    Anthony N. Hodder;Pauline E. Crewther;Mary L.S.M. Matthew;Gavin E. Reid

  • Distinct Protein Classes Including Novel Merozoite Surface Antigens in Raft-like Membranes of Plasmodium falciparum

    Paul R. Sanders;Paul R. Sanders;Paul R. Gilson;Greg T. Cantin;Doron C. Greenbaum

  • Identification and Prioritization of Merozoite Antigens as Targets of Protective Human Immunity to Plasmodium falciparum Malaria for Vaccine and Biomarker Development

    Jack Richards;Thangavelu U Arumugam;Linda Reiling;Julie Healer

  • Allelic polymorphisms in apical membrane antigen-1 are responsible for evasion of antibody-mediated inhibition in Plasmodium falciparum.

    Julie Healer;Vince Murphy;Anthony N. Hodder;Rosella Masciantonio

  • The malaria parasite Plasmodium falciparum has only one pyruvate dehydrogenase complex, which is located in the apicoplast

    Bernardo J. Foth;Luciana M. Stimmler;Emanuela Handman;Brendan S. Crabb

  • A Subset of Plasmodium falciparum SERA Genes Are Expressed and Appear to Play an Important Role in the Erythrocytic Cycle

    Susanne K. Miller;Robert T. Good;Damien R. Drew;Mauro Delorenzi

  • Inhibition of Plasmepsin V activity demonstrates its essential role in protein export, PfEMP1 display, and survival of malaria parasites.

    Brad E Sleebs;Sash Lopaticki;Danushka S. Marapana;Matthew T. O'Neill

  • Role of plasmepsin V in export of diverse protein families from the Plasmodium falciparum exportome.

    Justin A Boddey;Justin A Boddey;Teresa G Carvalho;Anthony N Hodder;Anthony N Hodder;Tobias J Sargeant

  • A human phase 1 vaccine clinical trial of the Plasmodium falciparum malaria vaccine candidate apical membrane antigen 1 in Montanide ISA720 adjuvant.

    Allan Saul;Greg Lawrence;Greg Lawrence;Anthony Allworth;Suzanne Elliott

  • Rapid and precise epitope mapping of monoclonal antibodies against Plasmodium falciparum AMA1 by combined phage display of fragments and random peptides.

    Andrew M. Coley;Naomi V. Campanale;Joanne L. Casey;Anthony N. Hodder

  • Structure of Domain III of the Blood-stage Malaria Vaccine Candidate, Plasmodium falciparum Apical Membrane Antigen 1 (AMA1)

    Margie Nair;Mark G. Hinds;Andrew M. Coley;Anthony N. Hodder

  • Enzymic, phylogenetic, and structural characterization of the unusual papain-like protease domain of Plasmodium falciparum SERA5.

    Anthony N. Hodder;Damien R. Drew;V. Chandana Epa;Mauro Delorenzi

  • Antigen delivery via two molecules on the CD8 dendritic cell subset induces humoral immunity in the absence of conventional "danger"

    Alexandra J. Corbett;Irina Caminschi;Brent S. McKenzie;Brent S. McKenzie;Jamie L. Brady

  • Plasmodium falciparum merozoite surface protein 2 is unstructured and forms amyloid-like fibrils

    Christopher G. Adda;Vince J. Murphy;Margaret Sunde;Lynne J. Waddington

  • Structural basis for plasmepsin V inhibition that blocks export of malaria proteins to human erythrocytes

    Anthony N Hodder;Brad E Sleebs;Peter E. Czabotar;Michelle Gazdik

  • Evidence for a Common Role for the Serine-Type Plasmodium falciparum Serine Repeat Antigen Proteases: Implications for Vaccine and Drug Design

    Joanne E. McCoubrie;Joanne E. McCoubrie;Susanne K. Miller;Susanne K. Miller;Tobias Sargeant;Tobias Sargeant;Robert T. Good

  • Identification of protein complexes in detergent-resistant membranes of Plasmodium falciparum schizonts

    Paul R. Sanders;Greg T. Cantin;Doron C. Greenbaum;Paul R. Gilson

Frequent Co-Authors

Alan F. Cowman
Alan F. Cowman Walter and Eliza Hall Institute of Medical Research
Robin F. Anders
Robin F. Anders La Trobe University
Brendan S. Crabb
Brendan S. Crabb Monash University
James G. Beeson
James G. Beeson Burnet Institute
Ivo Mueller
Ivo Mueller Walter and Eliza Hall Institute of Medical Research
Paul R. Gilson
Paul R. Gilson Burnet Institute
Brian J. Smith
Brian J. Smith QIMR Berghofer Medical Research Institute
Peter E. Czabotar
Peter E. Czabotar Walter and Eliza Hall Institute of Medical Research
Jack S. Richards
Jack S. Richards ZiP Diagnostics
Freya J. I. Fowkes
Freya J. I. Fowkes Burnet Institute

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