Jean-Noël Octave

Overview

Best Publications

• Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology.

  J Chapuis;F Hansmannel;M Gistelinck;A Mounier

  470
  Citations

• Aggregated Tau activates NLRP3-ASC inflammasome exacerbating exogenously seeded and non-exogenously seeded Tau pathology in vivo.

  Ilie-Cosmin Stancu;Niels Cremers;Hannah Vanrusselt;Julien Couturier

  411
  Citations

• Inhibitors of amyloid toxicity based on beta-sheet packing of Abeta40 and Abeta42.

  Takeshi Sato;Pascal Kienlen-Campard;Mahiuddin Ahmed;Wei Liu

  273
  Citations

• A novel mRNA of the A4 amyloid precursor gene coding for a possibly secreted protein

  F. de Sauvage;Jean-Noël Octave

  272
  Citations

• Transgenic expression of the shortest human tau affects its compartmentalization and its phosphorylation as in the pretangle stage of Alzheimer's disease.

  Jean-Pierre Brion;Gunter Tremp;Jean-Noël Octave

  248
  Citations

• Intracellular amyloid-beta 1-42, but not extracellular soluble amyloid-beta peptides, induces neuronal apoptosis.

  Pascal Kienlen-Campard;Sarah Miolet;Bernadette Tasiaux;Jean-Noël Octave

  233
  Citations

• Amyloidogenic Processing but Not Amyloid Precursor Protein (APP) Intracellular C-terminal Domain Production Requires a Precisely Oriented APP Dimer Assembled by Transmembrane GXXXG Motifs

  Pascal Kienlen-Campard;Bernadette Tasiaux;Joanne Van Hees;Mingli Li

  201
  Citations

• Iron uptake and utilization by mammalian cells. I: Cellular uptake of transferrin and iron

  Jean-Noël Octave;Yves-Jacques Schneider;André Trouet;Robert R. Crichton

  191
  Citations

• Heterotypic seeding of Tau fibrillization by pre-aggregated Abeta provides potent seeds for prion-like seeding and propagation of Tau-pathology in vivo

  Bruno Barbosa de Vasconcelos;Ilie-Cosmin Stancu;Arjan Buist;Matthew Bird

  187
  Citations

• Intraneuronal amyloid-beta1-42 production triggered by sustained increase of cytosolic calcium concentration induces neuronal death.

  Nathalie Pierrot;Philippe Ghisdal;Anne-Sophie Caumont;Jean-Noël Octave

  174
  Citations

• Distribution of the phosphorylated microtubule-associated protein tau in developing cortical neurons.

  Jean Pierre Brion;Jean Noël Octave;A M Couck

  167
  Citations

• Lack of tau proteins rescues neuronal cell death and decreases amyloidogenic processing of APP in APP/PS1 mice.

  Karelle Leroy;Kunie Ando;Vincent Laporte;Robert Dedecker

  160
  Citations

• Neurofibrillary tangles and tau phosphorylation.

  Jean-Pierre Brion;Brian H. Anderton;Michéle Authelet;Rejith Dayanandan

  156
  Citations

• Templated misfolding of Tau by prion-like seeding along neuronal connections impairs neuronal network function and associated behavioral outcomes in Tau transgenic mice.

  Ilie-Cosmin Stancu;Bruno Barbosa de Vasconcelos;Laurence Ris;Peng Wang

  154
  Citations

• Molecular identification of aspartate N-acetyltransferase and its mutation in hypoacetylaspartia

  Elsa Wiame;Donatienne Tyteca;Nathalie Pierrot;François Collard

  153
  Citations

• Transferrin uptake by cultured rat embryo fibroblasts. The influence of temperature and incubation time, subcellular distribution and short-term kinetic studies.

  Jean-Noël Octave;Yves-Jacques Schneider;Robert Crichton;André Trouet

  150
  Citations

• Calcium-mediated transient phosphorylation of tau and amyloid precursor protein followed by intraneuronal amyloid-beta accumulation.

  Nathalie Pierrot;Susana Ferrao Santos;Christine Feyt;Marina Morel

  148
  Citations

• A helix-to-coil transition at the ε-cut site in the transmembrane dimer of the amyloid precursor protein is required for proteolysis

  Takeshi Sato;Tzu-chun Tang;Gabriella Reubins;Jeffrey Z. Fei

  139
  Citations

• Transforming growth factor beta as a neuronoglial signal during peripheral nervous system response to injury.

  B. Rogister;P. Delrée;P. Leprince;D. Martin

  136
  Citations

• Nucleotide sequence of cDNA coding for rat liver pI 6.1 esterase (ES-10), a carboxylesterase located in the lumen of the endoplasmic reticulum.

  Mariette Robbi;Henri Beaufay;Jean-Noël Octave

  135
  Citations