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Jean-Noël Octave

D-Index & Metrics

Biology and Biochemistry

D-Index
48
Citations
8318
World Ranking
18393
National Ranking
304

Jean-Noël Octave publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Jean-Noël Octave sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 229 publications — 61st percentile

61% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Jean-Noël Octave D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Jean-Noël Octave sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 48 D-Index — 7th percentile

7% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Jean-Noël Octave is affiliated with the Université Catholique de Louvain in Belgium. Their research focuses primarily on neuroscience and medicine, with specific expertise in physiology, cellular and molecular neuroscience, molecular biology, neurology, and psychiatry and mental health.

The scientist has contributed to research in several main topics, including:

  • Alzheimer's disease research and treatments
  • Neuroscience and Neuropharmacology Research
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Peroxisome Proliferator-Activated Receptors
  • Dementia and Cognitive Impairment Research
  • Tryptophan and brain disorders
  • Cholesterol and Lipid Metabolism

Jean-Noël Octave has published work in multiple scientific journals. Notable publication venues include:

  • Acta Neuropathologica Communications
  • JCI Insight
  • Cells
  • eNeuro
  • Scientific Reports

Their recent papers demonstrate an engagement with neurodegenerative diseases and molecular mechanisms associated with them. These works include:

  • "CSF1R inhibition rescues tau pathology and neurodegeneration in an A/T/N model with combined AD pathologies, while preserving plaque associated microglia" (2021), Acta Neuropathologica Communications
  • "Alzheimer's Disease, a Lipid Story: Involvement of Peroxisome Proliferator-Activated Receptor α" (2020), Cells
  • "Amyloid Precursor Protein (APP) Controls the Expression of the Transcriptional Activator Neuronal PAS Domain Protein 4 (NPAS4) and Synaptic GABA Release" (2020), eNeuro
  • "Regulation of PPARα by APP in Alzheimer disease affects the pharmacological modulation of synaptic activity" (2021), JCI Insight
  • "Overexpression of wild-type human amyloid precursor protein alters GABAergic transmission" (2021), Scientific Reports

Frequent collaborators in their research include Nathalie Pierrot, Philippe Gailly, Anna Kreis, Roberta Gualdani, and Francisco Sáez-Orellana.

Best Publications

  • Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology.

    J Chapuis;F Hansmannel;M Gistelinck;A Mounier

  • Aggregated Tau activates NLRP3-ASC inflammasome exacerbating exogenously seeded and non-exogenously seeded Tau pathology in vivo.

    Ilie-Cosmin Stancu;Niels Cremers;Hannah Vanrusselt;Julien Couturier

  • Inhibitors of amyloid toxicity based on beta-sheet packing of Abeta40 and Abeta42.

    Takeshi Sato;Pascal Kienlen-Campard;Mahiuddin Ahmed;Wei Liu

  • A novel mRNA of the A4 amyloid precursor gene coding for a possibly secreted protein

    F. de Sauvage;Jean-Noël Octave

  • Transgenic expression of the shortest human tau affects its compartmentalization and its phosphorylation as in the pretangle stage of Alzheimer's disease.

    Jean-Pierre Brion;Gunter Tremp;Jean-Noël Octave

  • Intracellular amyloid-beta 1-42, but not extracellular soluble amyloid-beta peptides, induces neuronal apoptosis.

    Pascal Kienlen-Campard;Sarah Miolet;Bernadette Tasiaux;Jean-Noël Octave

  • Amyloidogenic Processing but Not Amyloid Precursor Protein (APP) Intracellular C-terminal Domain Production Requires a Precisely Oriented APP Dimer Assembled by Transmembrane GXXXG Motifs

    Pascal Kienlen-Campard;Bernadette Tasiaux;Joanne Van Hees;Mingli Li

  • Iron uptake and utilization by mammalian cells. I: Cellular uptake of transferrin and iron

    Jean-Noël Octave;Yves-Jacques Schneider;André Trouet;Robert R. Crichton

  • Heterotypic seeding of Tau fibrillization by pre-aggregated Abeta provides potent seeds for prion-like seeding and propagation of Tau-pathology in vivo

    Bruno Barbosa de Vasconcelos;Ilie-Cosmin Stancu;Arjan Buist;Matthew Bird

  • Intraneuronal amyloid-beta1-42 production triggered by sustained increase of cytosolic calcium concentration induces neuronal death.

    Nathalie Pierrot;Philippe Ghisdal;Anne-Sophie Caumont;Jean-Noël Octave

  • Distribution of the phosphorylated microtubule-associated protein tau in developing cortical neurons.

    Jean Pierre Brion;Jean Noël Octave;A M Couck

  • Lack of tau proteins rescues neuronal cell death and decreases amyloidogenic processing of APP in APP/PS1 mice.

    Karelle Leroy;Kunie Ando;Vincent Laporte;Robert Dedecker

  • Neurofibrillary tangles and tau phosphorylation.

    Jean-Pierre Brion;Brian H. Anderton;Michéle Authelet;Rejith Dayanandan

  • Templated misfolding of Tau by prion-like seeding along neuronal connections impairs neuronal network function and associated behavioral outcomes in Tau transgenic mice.

    Ilie-Cosmin Stancu;Bruno Barbosa de Vasconcelos;Laurence Ris;Peng Wang

  • Molecular identification of aspartate N-acetyltransferase and its mutation in hypoacetylaspartia

    Elsa Wiame;Donatienne Tyteca;Nathalie Pierrot;François Collard

  • Transferrin uptake by cultured rat embryo fibroblasts. The influence of temperature and incubation time, subcellular distribution and short-term kinetic studies.

    Jean-Noël Octave;Yves-Jacques Schneider;Robert Crichton;André Trouet

  • Calcium-mediated transient phosphorylation of tau and amyloid precursor protein followed by intraneuronal amyloid-beta accumulation.

    Nathalie Pierrot;Susana Ferrao Santos;Christine Feyt;Marina Morel

  • A helix-to-coil transition at the ε-cut site in the transmembrane dimer of the amyloid precursor protein is required for proteolysis

    Takeshi Sato;Tzu-chun Tang;Gabriella Reubins;Jeffrey Z. Fei

  • Transforming growth factor beta as a neuronoglial signal during peripheral nervous system response to injury.

    B. Rogister;P. Delrée;P. Leprince;D. Martin

  • Nucleotide sequence of cDNA coding for rat liver pI 6.1 esterase (ES-10), a carboxylesterase located in the lumen of the endoplasmic reticulum.

    Mariette Robbi;Henri Beaufay;Jean-Noël Octave

Frequent Co-Authors

André Trouet
André Trouet Université Catholique de Louvain
Yves-Jacques Schneider
Yves-Jacques Schneider Université Catholique de Louvain
Robert R. Crichton
Robert R. Crichton Université Catholique de Louvain
Stefan N. Constantinescu
Stefan N. Constantinescu Ludwig Cancer Research
Pierre J. Courtoy
Pierre J. Courtoy Université Catholique de Louvain
Steven O. Smith
Steven O. Smith Stony Brook University
Jean-Christophe Renauld
Jean-Christophe Renauld Université Catholique de Louvain
Diederik Moechars
Diederik Moechars Janssen (Belgium)
Bart De Strooper
Bart De Strooper KU Leuven
Joëlle Quetin-Leclercq
Joëlle Quetin-Leclercq Université Catholique de Louvain

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