D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 40 Citations 5,774 129 World Ranking 16619 National Ranking 280

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • Biochemistry

His main research concerns Biochemistry, Molecular biology, Intracellular, Extracellular and Transferrin. His study in Ferritin, Endocytosis, DNA, Endocytic cycle and Cell fractionation falls within the category of Biochemistry. André Trouet has researched Molecular biology in several fields, including Nucleotidase, Cytoplasm, Antibody and 5'-nucleotidase.

The Intracellular study which covers Membrane that intersects with Horseradish peroxidase, Immunoglobulin G, Cell and Biophysics. Extracellular is often connected to Daunorubicin in his work. André Trouet combines subjects such as Endocytic vesicle and Iron uptake with his study of Transferrin.

His most cited work include:

  • Commentary. Lysosomotropic agents. (1554 citations)
  • A covalent linkage between daunorubicin and proteins that is stable in serum and reversible by lysosomal hydrolases, as required for a lysosomotropic drug-carrier conjugate: in vitro and in vivo studies. (281 citations)
  • Chemotherapy through lysosomes with a DNA-daunorubicin complex. (248 citations)

What are the main themes of his work throughout his whole career to date?

André Trouet focuses on Biochemistry, Pharmacology, Daunorubicin, Cell biology and Endocytosis. André Trouet regularly links together related areas like Molecular biology in his Biochemistry studies. His work deals with themes such as Antibody and Intracellular, which intersect with Molecular biology.

His studies deal with areas such as Chemotherapy and Toxicity as well as Pharmacology. His Daunorubicin study also includes

  • Doxorubicin which intersects with area such as Prodrug and Chromatography,
  • DNA together with Drug. As a part of the same scientific study, André Trouet usually deals with the Endocytosis, concentrating on Membrane and frequently concerns with Biophysics.

He most often published in these fields:

  • Biochemistry (38.40%)
  • Pharmacology (18.00%)
  • Daunorubicin (17.60%)

What were the highlights of his more recent work (between 1994-2017)?

  • Biochemistry (38.40%)
  • Prodrug (6.40%)
  • Pharmacology (18.00%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Biochemistry, Prodrug, Pharmacology, Stereochemistry and Internal medicine. His Biochemistry study combines topics in areas such as Cell culture and Intestinal mucosa. His Prodrug research incorporates elements of Cleavage, Tetrapeptide and Doxorubicin.

His study in Pharmacology is interdisciplinary in nature, drawing from both Immunology, Toxicity and In vivo. André Trouet works mostly in the field of Stereochemistry, limiting it down to topics relating to Active site and, in certain cases, Molecular biology, as a part of the same area of interest. His Internal medicine research focuses on Endocrinology and how it connects with Cancer cell, Cell type and Cell.

Between 1994 and 2017, his most popular works were:

  • Transferrin uptake by cultured rat embryo fibroblasts. The influence of temperature and incubation time, subcellular distribution and short-term kinetic studies. (122 citations)
  • Extracellularly tumor-activated prodrugs for the selective chemotherapy of cancer: application to doxorubicin and preliminary in vitro and in vivo studies. (82 citations)
  • Interaction of ochratoxin A with human intestinal Caco-2 cells: possible implication of a multidrug resistance-associated protein (MRP2). (81 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Biochemistry

The scientist’s investigation covers issues in Prodrug, Biochemistry, Pharmacology, Toxicity and Doxorubicin. His work carried out in the field of Prodrug brings together such families of science as Ligand, Active site, Molecular biology, Stereochemistry and Intracellular. His research on Biochemistry frequently connects to adjacent areas such as Intestinal mucosa.

His Pharmacology research is multidisciplinary, incorporating elements of Adjuvant, Oligopeptide, Reduced toxicity and Tumor cells. His Doxorubicin research includes themes of Endocrinology and In vivo. André Trouet has included themes like Extracellular matrix, Cell biology and Cell type in his Internal medicine study.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

A covalent linkage between daunorubicin and proteins that is stable in serum and reversible by lysosomal hydrolases, as required for a lysosomotropic drug-carrier conjugate: in vitro and in vivo studies.

Andre Trouet;Michele Masquelier;Roger Baurain;Danielle Deprez-de Campeneere.
Proceedings of the National Academy of Sciences of the United States of America (1982)

433 Citations

Chemotherapy through lysosomes with a DNA-daunorubicin complex.

André Trouet;Danielè Deprez-De Campeneere;Christian De Duve.
Nature (1972)

374 Citations

Nanocapsules: A new type of lysosomotropic carrier

P. Couvreur;P. Tulkenst;M. Roland;A. Trouet.
FEBS Letters (1977)

237 Citations

The uptake and intracellular accumulation of aminoglycoside antibiotics in lysosomes of cultured rat fibroblasts.

Paul Tulkens;AndrÉ Trouet.
Biochemical Pharmacology (1978)

206 Citations

Evidence for a continual exchange of 5′-nucleotidase between the cell surface and cytoplasmic membranes in cultured rat fibroblasts

Christopher C. Widnell;Yves-Jacques Schneider;Bernadette Pierre;Pierre Baudhuin.
Cell (1982)

181 Citations

Iron uptake and utilization by mammalian cells. I: Cellular uptake of transferrin and iron

Jean-Noël Octave;Yves-Jacques Schneider;André Trouet;Robert R. Crichton.
Trends in Biochemical Sciences (1983)

179 Citations

ANALYTICAL FRACTIONATION OF HOMOGENATES FROM CULTURED RAT EMBRYO FIBROBLASTS

Paul Tulkens;Henry Beaufay;André Trouet.
Journal of Cell Biology (1974)

177 Citations

Fate of plasma membrane during endocytosis. II. Evidence for recycling (shuttle) of plasma membrane constituents

Y J Schneider;P Tulkens;C de Duve;A Trouet.
Journal of Cell Biology (1979)

163 Citations

Process for preparing lipid microparticles

Trouet Andre;Leclef Brigitte;Cerfontaine Patrick;Nicolas Jean-Marie.
(1990)

145 Citations

Transferrin uptake by cultured rat embryo fibroblasts. The influence of temperature and incubation time, subcellular distribution and short-term kinetic studies.

Jean-Noël Octave;Yves-Jacques Schneider;Robert Crichton;André Trouet.
FEBS Journal (2005)

141 Citations

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