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Marie-Paule Mingeot-Leclercq

Marie-Paule Mingeot-Leclercq

D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
11050
World Ranking
13895
National Ranking
249

Overview

Marie-Paule Mingeot-Leclercq is affiliated with the Université Catholique de Louvain in Belgium. Their research spans multiple fields, primarily within Biochemistry, Genetics and Molecular Biology, with notable contributions also in Medicine.

The scientist's work covers diverse subfields such as Molecular Biology, Molecular Medicine, Plant Science, Microbiology, and Organic Chemistry. Their research topics include:

  • Antibiotic Resistance in Bacteria
  • Lipid Membrane Structure and Behavior
  • Bacterial biofilms and quorum sensing
  • Phenothiazines and Benzothiazines Synthesis and Activities
  • Bacterial Infections and Vaccines
  • Legionella and Acanthamoeba research
  • Plant Pathogenic Bacteria Studies

Recent publications illustrate the breadth of their research interests. Examples include:

  • Membrane Vesicle Production as a Bacterial Defense Against Stress, 2020, Frontiers in Microbiology
  • On the use of antibiotics to control plant pathogenic bacteria: a genetic and genomic perspective, 2023, Frontiers in Microbiology
  • Label-Free Imaging of Cholesterol Assemblies Reveals Hidden Nanomechanics of Breast Cancer Cells, 2020, Advanced Science
  • Surfactant Protein B Promotes Cytosolic SiRNA Delivery by Adopting a Virus-like Mechanism of Action, 2021, ACS Nano
  • Surface cholesterol-enriched domains specifically promote invasion of breast cancer cell lines by controlling invadopodia and extracellular matrix degradation, 2022, Cellular and Molecular Life Sciences

The scientist frequently publishes in venues such as ChemMedChem, Frontiers in Microbiology, International Journal of Molecular Sciences, Microbiology Spectrum, and Frontiers in Physiology. These journals reflect a wide engagement with both biochemical and microbiological disciplines.

Collaborations contribute a significant aspect to their research profile. Frequent co-authors include Negar Mozaheb, Jean-Luc Décout, Sandrine L. Verstraeten, Donatienne Tyteca, and Patrick Van Deŕ Smissen. Such collaborations indicate interdisciplinary teamwork bridging microbiology, molecular biology, and chemistry.

Best Publications

  • Aminoglycosides: Activity and Resistance

    Marie-Paule Mingeot-Leclercq;Youri Glupczynski;Paul M. Tulkens

  • Pharmacodynamic Evaluation of the Intracellular Activities of Antibiotics against Staphylococcus aureus in a Model of THP-1 Macrophages

    Maritza Barcia-Macay;Cristina Seral;Marie-Paule Mingeot-Leclercq;Paul M. Tulkens

  • The amphiphilic nature of saponins and their effects on artificial and biological membranes and potential consequences for red blood and cancer cells

    Joseph H. Lorent;Joëlle Quetin-Leclercq;Marie-Paule Mingeot-Leclercq

  • Comparative Stability Studies of Antipseudomonal β-Lactams for Potential Administration through Portable Elastomeric Pumps (Home Therapy for Cystic Fibrosis Patients) and Motor-Operated Syringes (Intensive Care Units)

    Eric Viaene;Hugues Chanteux;Hélène Servais;Marie-Paule Mingeot-Leclercq

  • Atomic force microscopy of supported lipid bilayers.

    Marie -Paule Mingeot-Leclercq;Magali Deleu;Robert Brasseur;Yves F Dufrene

  • Intracellular pharmacodynamics of antibiotics

    Stéphane Carryn;Hugues Chanteux;Cristina Seral;Marie-Paule Mingeot-Leclercq

  • Renal cell apoptosis induced by nephrotoxic drugs: cellular and molecular mechanisms and potential approaches to modulation

    Hélène Servais;Alberto Ortiz;Olivier Devuyst;Sophie Denamur

  • Direct Observation of Staphylococcus aureus Cell Wall Digestion by Lysostaphin

    Grégory Francius;Oscar Domenech;Marie Paule Mingeot-Leclercq;Yves F. Dufrêne

  • Comparative Intracellular (THP-1 Macrophage) and Extracellular Activities of β-Lactams, Azithromycin, Gentamicin, and Fluoroquinolones against Listeria monocytogenes at Clinically Relevant Concentrations

    Stéphane Carryn;Françoise Van Bambeke;Marie-Paule Mingeot-Leclercq;Paul M. Tulkens

  • Apoptosis in renal proximal tubules of rats treated with low doses of aminoglycosides.

    Mohammed El Mouedden;Guy Laurent;Marie-Paule Mingeot-Leclercq;Henryk S. Taper

  • The bacterial envelope as a target for novel anti-MRSA antibiotics.

    Françoise Van Bambeke;Marie-Paule Mingeot-Leclercq;Marc J. Struelens;Paul M. Tulkens

  • Gentamicin-induced apoptosis in LLC-PK1 cells : Involvement of lysosomes and mitochondria

    Hélène Servais;Patrick Van Der Smissen;Gaëtan Thirion;Gauthier Van Der Essen

  • Cellular uptake of Antennapedia Penetratin peptides is a two-step process in which phase transfer precedes a tryptophan-dependent translocation.

    Geneviève Dom;Chloë Shaw-Jackson;Christelle Matis;Olivier Bouffioux

  • Bacterial lipid membranes as promising targets to fight antimicrobial resistance, molecular foundations and illustration through the renewal of aminoglycoside antibiotics and emergence of amphiphilic aminoglycosides

    Marie-Paule Mingeot-Leclercq;Jean-Luc Décout

  • Effects of surfactin on membrane models displaying lipid phase separation.

    Magali Deleu;Joseph Lorent;Laurence Lins;Robert Brasseur

  • Evaluation of the extracellular and intracellular activities (human THP-1 macrophages) of telavancin versus vancomycin against methicillin-susceptible, methicillin-resistant, vancomycin-intermediate and vancomycin-resistant Staphylococcus aureus

    Maritza Barcia-Macay;Sandrine Lemaire;Marie-Paule Mingeot-Leclercq;Paul M Tulkens

  • Gentamicin-Induced Apoptosis in Renal Cell Lines and Embryonic Rat Fibroblasts

    Mohammed El Mouedden;Guy Laurent;Marie-Paule Mingeot-Leclercq;Paul M. Tulkens

  • Combined effect of pH and concentration on the activities of gentamicin and oxacillin against Staphylococcus aureus in pharmacodynamic models of extracellular and intracellular infections.

    Pierre Baudoux;Nathalie Bles;Sandrine Lemaire;Marie-Paule Mingeot-Leclercq

  • Comparison of the Antibiotic Activities of Daptomycin, Vancomycin, and the Investigational Fluoroquinolone Delafloxacin against Biofilms from Staphylococcus aureus Clinical Isolates

    Wafi Siala;Marie-Paule Mingeot-Leclercq;Paul M. Tulkens;Marie Hallin

  • Targeting the Type Three Secretion System in Pseudomonas aeruginosa

    Ahalieyah Anantharajah;Marie-Paule Mingeot-Leclercq;Françoise Van Bambeke

Frequent Co-Authors

Paul M. Tulkens
Paul M. Tulkens Université Catholique de Louvain
Françoise Van Bambeke
Françoise Van Bambeke Université Catholique de Louvain
Joëlle Quetin-Leclercq
Joëlle Quetin-Leclercq Université Catholique de Louvain
Robert Brasseur
Robert Brasseur Université Libre de Bruxelles
Yves F. Dufrêne
Yves F. Dufrêne Université Catholique de Louvain
Laurence Lins
Laurence Lins Gembloux Agro-Bio Tech
Pierre J. Courtoy
Pierre J. Courtoy Université Catholique de Louvain
Youri Glupczynski
Youri Glupczynski Université Catholique de Louvain
Véronique Préat
Véronique Préat Université Catholique de Louvain
Erik Goormaghtigh
Erik Goormaghtigh Université Libre de Bruxelles

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