D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 48 Citations 11,218 117 World Ranking 13972 National Ranking 239

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Biochemistry
  • Internal medicine

Pierre M. Laduron spends much of his time researching Receptor, Pharmacology, Endocrinology, Internal medicine and Serotonin. His Receptor research is multidisciplinary, incorporating perspectives in Dopamine and Binding site. His Pharmacology research includes themes of Neuroleptic Drugs, Antagonist, Spiperone and Ligand binding assay.

His Dopaminergic and Vagus nerve study in the realm of Endocrinology interacts with subjects such as Levocabastine. His studies in Internal medicine integrate themes in fields like Differential centrifugation and Antihistamine. Specifically, his work in Serotonin is concerned with the study of Ketanserin.

His most cited work include:

  • [3H]Ketanserin (R 41 468), a selective 3H-ligand for serotonin2 receptor binding sites. Binding properties, brain distribution, and functional role. (1021 citations)
  • Receptor binding profile of R 41 468, A novel antagonist at 5-HT2 receptors (774 citations)
  • Serotonergic component of neuroleptic receptors (602 citations)

What are the main themes of his work throughout his whole career to date?

Receptor, Internal medicine, Endocrinology, Biochemistry and Pharmacology are his primary areas of study. His biological study spans a wide range of topics, including Neuroscience and Binding site. His research on Internal medicine often connects related topics like Cell biology.

His work in the fields of Digitonin, Differential centrifugation and Solubilization overlaps with other areas such as Subcellular localization. His Pharmacology study combines topics from a wide range of disciplines, such as Haloperidol, Pimozide and Antagonist. His studies examine the connections between Spiperone and genetics, as well as such issues in Ketanserin, with regards to Ligand.

He most often published in these fields:

  • Receptor (37.50%)
  • Internal medicine (35.16%)
  • Endocrinology (35.16%)

What were the highlights of his more recent work (between 1987-2011)?

  • Neuroscience (17.19%)
  • Pharmacology (23.44%)
  • Axoplasmic transport (11.72%)

In recent papers he was focusing on the following fields of study:

Pierre M. Laduron focuses on Neuroscience, Pharmacology, Axoplasmic transport, Psychiatry and Sleep in non-human animals. His study in Neuroscience is interdisciplinary in nature, drawing from both Schizophrenia, Presynaptic receptors, Autoreceptor and Potassium channel. The concepts of his Pharmacology study are interwoven with issues in Electrophysiology, Incidence, Neuroleptic Drugs and Receptor, Dopamine receptor.

His Receptor study incorporates themes from Stimulation and Anatomy. His Axoplasmic transport research includes elements of Rat brain, Homeostasis, Tissue distribution, Axon and Sciatic nerve. His work on Depression is typically connected to Production and Process as part of general Psychiatry study, connecting several disciplines of science.

Between 1987 and 2011, his most popular works were:

  • Pharmacological properties of a potent and selective nonpeptide substance P antagonist. (389 citations)
  • Different subcellular localization of neurotensin-receptor and neurotensin-acceptor sites in the rat brain dopaminergic system. (64 citations)
  • Is the low incidence of extrapyramidal side-effects of antipsychotics associated with antimuscarinic properties? (38 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Biochemistry
  • Internal medicine

Pierre M. Laduron mainly investigates Pharmacology, Receptor, Electrophysiology, Basal ganglia disease and Parasympatholytics. His Pharmacology study integrates concerns from other disciplines, such as Cerebral cortex, Stimulation, Neuroscience and Biological activity. His research on Receptor frequently links to adjacent areas such as Anatomy.

His biological study spans a wide range of topics, including Potency, Stereochemistry and Central nervous system. A majority of his Basal ganglia disease research is a blend of other scientific areas, such as Dexetimide and Incidence.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

[3H]Ketanserin (R 41 468), a selective 3H-ligand for serotonin2 receptor binding sites. Binding properties, brain distribution, and functional role.

J E Leysen;C J Niemegeers;J M Van Nueten;P M Laduron.
Molecular Pharmacology (1982)

1401 Citations

Receptor binding profile of R 41 468, A novel antagonist at 5-HT2 receptors

J.E. Leysen;F. Awouters;L. Kennis;P.M. Laduron.
Life Sciences (1981)

1218 Citations

Serotonergic component of neuroleptic receptors

Josée E. Leysen;Carlos J. E. Niemegeers;Jan P. Tollenaere;Pierre M. Laduron.
Nature (1978)

952 Citations

Spiperone: a ligand of choice for neuroleptic receptors. 1. Kinetics and characteristics of in vitro binding.

Josée E. Leysen;W. Gommeren;Pierre M. Laduron.
Biochemical Pharmacology (1978)

784 Citations

Receptor-binding properties in vitro and in vivo of ritanserin: A very potent and long acting serotonin-S2 antagonist.

J. E. Leysen;W. Gommeren;P. Van Gompel;J. Wynants.
Molecular Pharmacology (1985)

644 Citations

Pharmacological properties of a potent and selective nonpeptide substance P antagonist.

Claude Garret;Anne Carruette;Veronique Fardin;Saliha Moussaoui.
Proceedings of the National Academy of Sciences of the United States of America (1991)

599 Citations

Domperidone, a specific in vitro dopamine antagonist, devoid of in vivo central dopaminergic activity.

Pierre M. Laduron;Josée E. Leysen.
Biochemical Pharmacology (1979)

559 Citations

Spiperone: A ligand of choice for neuroleptic receptors: 2. Regional distribution and in vivo displacement of neuroleptic drugs

Pierre M. Laduron;P.F.M. Janssen;Josée E. Leysen.
Biochemical Pharmacology (1978)

250 Citations

Evidence for a displaceable non-specific [3H]neurotensin binding site in rat brain.

A. Schotte;J. E. Leysen;P. M. Laduron.
Naunyn-schmiedebergs Archives of Pharmacology (1986)

216 Citations

Axonal transport of opiate receptors in capsaicin-sensitive neurones

Pierre M. Laduron.
Brain Research (1984)

203 Citations

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