Pierre M. Laduron spends much of his time researching Receptor, Pharmacology, Endocrinology, Internal medicine and Serotonin. His Receptor research is multidisciplinary, incorporating perspectives in Dopamine and Binding site. His Pharmacology research includes themes of Neuroleptic Drugs, Antagonist, Spiperone and Ligand binding assay.
His Dopaminergic and Vagus nerve study in the realm of Endocrinology interacts with subjects such as Levocabastine. His studies in Internal medicine integrate themes in fields like Differential centrifugation and Antihistamine. Specifically, his work in Serotonin is concerned with the study of Ketanserin.
Receptor, Internal medicine, Endocrinology, Biochemistry and Pharmacology are his primary areas of study. His biological study spans a wide range of topics, including Neuroscience and Binding site. His research on Internal medicine often connects related topics like Cell biology.
His work in the fields of Digitonin, Differential centrifugation and Solubilization overlaps with other areas such as Subcellular localization. His Pharmacology study combines topics from a wide range of disciplines, such as Haloperidol, Pimozide and Antagonist. His studies examine the connections between Spiperone and genetics, as well as such issues in Ketanserin, with regards to Ligand.
Pierre M. Laduron focuses on Neuroscience, Pharmacology, Axoplasmic transport, Psychiatry and Sleep in non-human animals. His study in Neuroscience is interdisciplinary in nature, drawing from both Schizophrenia, Presynaptic receptors, Autoreceptor and Potassium channel. The concepts of his Pharmacology study are interwoven with issues in Electrophysiology, Incidence, Neuroleptic Drugs and Receptor, Dopamine receptor.
His Receptor study incorporates themes from Stimulation and Anatomy. His Axoplasmic transport research includes elements of Rat brain, Homeostasis, Tissue distribution, Axon and Sciatic nerve. His work on Depression is typically connected to Production and Process as part of general Psychiatry study, connecting several disciplines of science.
Pierre M. Laduron mainly investigates Pharmacology, Receptor, Electrophysiology, Basal ganglia disease and Parasympatholytics. His Pharmacology study integrates concerns from other disciplines, such as Cerebral cortex, Stimulation, Neuroscience and Biological activity. His research on Receptor frequently links to adjacent areas such as Anatomy.
His biological study spans a wide range of topics, including Potency, Stereochemistry and Central nervous system. A majority of his Basal ganglia disease research is a blend of other scientific areas, such as Dexetimide and Incidence.
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[3H]Ketanserin (R 41 468), a selective 3H-ligand for serotonin2 receptor binding sites. Binding properties, brain distribution, and functional role.
J E Leysen;C J Niemegeers;J M Van Nueten;P M Laduron.
Molecular Pharmacology (1982)
Receptor binding profile of R 41 468, A novel antagonist at 5-HT2 receptors
J.E. Leysen;F. Awouters;L. Kennis;P.M. Laduron.
Life Sciences (1981)
Serotonergic component of neuroleptic receptors
Josée E. Leysen;Carlos J. E. Niemegeers;Jan P. Tollenaere;Pierre M. Laduron.
Nature (1978)
Spiperone: a ligand of choice for neuroleptic receptors. 1. Kinetics and characteristics of in vitro binding.
Josée E. Leysen;W. Gommeren;Pierre M. Laduron.
Biochemical Pharmacology (1978)
Receptor-binding properties in vitro and in vivo of ritanserin: A very potent and long acting serotonin-S2 antagonist.
J. E. Leysen;W. Gommeren;P. Van Gompel;J. Wynants.
Molecular Pharmacology (1985)
Pharmacological properties of a potent and selective nonpeptide substance P antagonist.
Claude Garret;Anne Carruette;Veronique Fardin;Saliha Moussaoui.
Proceedings of the National Academy of Sciences of the United States of America (1991)
Domperidone, a specific in vitro dopamine antagonist, devoid of in vivo central dopaminergic activity.
Pierre M. Laduron;Josée E. Leysen.
Biochemical Pharmacology (1979)
Spiperone: A ligand of choice for neuroleptic receptors: 2. Regional distribution and in vivo displacement of neuroleptic drugs
Pierre M. Laduron;P.F.M. Janssen;Josée E. Leysen.
Biochemical Pharmacology (1978)
Evidence for a displaceable non-specific [3H]neurotensin binding site in rat brain.
A. Schotte;J. E. Leysen;P. M. Laduron.
Naunyn-schmiedebergs Archives of Pharmacology (1986)
Axonal transport of opiate receptors in capsaicin-sensitive neurones
Pierre M. Laduron.
Brain Research (1984)
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