Josée E. Leysen

Overview

Best Publications

• Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding

  A. Schotte;P. F. M. Janssen;W. Gommeren;W. H. M. L. Luyten

  1415
  Citations

• Receptor binding profile of R 41 468, A novel antagonist at 5-HT2 receptors

  J.E. Leysen;F. Awouters;L. Kennis;P.M. Laduron

  1232
  Citations

• Serotonergic component of neuroleptic receptors

  Josée E. Leysen;Carlos J. E. Niemegeers;Jan P. Tollenaere;Pierre M. Laduron

  955
  Citations

• Spiperone: a ligand of choice for neuroleptic receptors. 1. Kinetics and characteristics of in vitro binding.

  Josée E. Leysen;W. Gommeren;Pierre M. Laduron

  785
  Citations

• Domperidone, a specific in vitro dopamine antagonist, devoid of in vivo central dopaminergic activity.

  Pierre M. Laduron;Josée E. Leysen

  566
  Citations

• Interaction of antipsychotic drugs with neurotransmitter receptor sites in vitro and in vivo in relation to pharmacological and clinical effects: role of 5HT2 receptors

  Josée E. Leysen;Paul M. F. Janssen;Alain Schotte;Walter H. M. L. Luyten

  425
  Citations

• 5-HT2 receptors.

  J E Leysen

  336
  Citations

• 5-HT7 receptors: current knowledge and future prospects.

  Peter Vanhoenacker;Guy Haegeman;Josée E Leysen

  298
  Citations

• 5-HT2A and 5-HT2C receptors and their atypical regulation properties

  Dirk Van Oekelen;Walter H.M.L Luyten;Josée E Leysen

  293
  Citations

• [3H]sufentanil, a superior ligand for μ-opiate receptors: Binding properties and regional distribution in rat brain and spinal cord

  Josee E. Leysen;Walter Gommeren;Carlos J.E. Niemegeers

  253
  Citations

• Expression and regulation of interleukin-10 and interleukin-10 receptor in rat astroglial and microglial cells.

  Annemarie Ledeboer;John J. P. Brevé;Anne Wierinckx;Saskia Van Der Jagt

  250
  Citations

• Spiperone: A ligand of choice for neuroleptic receptors: 2. Regional distribution and in vivo displacement of neuroleptic drugs

  Pierre M. Laduron;P.F.M. Janssen;Josée E. Leysen

  244
  Citations

• Regional brain distribution of risperidone and its active metabolite 9-hydroxy-risperidone in the rat

  Ludy E. C. van Beijsterveldt;Rita J. F. Geerts;Josée E. Leysen;Anton A. H. P. Megens

  232
  Citations

• Genomic cloning, heterologous expression and pharmacological characterization of a human histamine H1 receptor

  M. D. De Backer;W. Gommeren;H. Moereels;G. Nobels

  225
  Citations

• Evidence for a displaceable non-specific [3H]neurotensin binding site in rat brain.

  A. Schotte;J. E. Leysen;P. M. Laduron

  221
  Citations

• The in vitro pharmacological profile of prucalopride, a novel enterokinetic compound.

  Michel R Briejer;Jean-Paul Bosmans;Paul Van Daele;Mirek Jurzak

  208
  Citations

• Functional role of 5-HT2 receptors in the regulation of sleep and wakefulness in the rat.

  Christine Dugovic;Albert Wauquier;Josee E. Leysen;Roger Marrannes

  193
  Citations

• Optimal Conditions for [3H]Apomorphine Binding and Anomalous Equilibrium Binding of [3H]Apomorphine and [3H]Spiperone to Rat Striatal Membranes: Involvement of Surface Phenomena Versus Multiple Binding Sites

  Josée E. Leysen;Walter Gommeren

  186
  Citations

• Nuclei and subnuclei gene expression profiling in mammalian brain.

  Pascal Bonaventure;Hongqing Guo;Bin Tian;Xuejun Liu

  179
  Citations

• A serotonergic component of neuroleptic receptors.

  Leysen Je;Laduron Pm

  23
  Citations