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Medicine

D-Index
122
Citations
52256
World Ranking
3492
National Ranking
1921

Research.com Recognitions

  • 2014 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2011 - Member of the National Academy of Medicine (NAM)

Overview

Jay S. Loeffler is affiliated with Harvard University in the United States and has contributed extensively to the field of medicine, with a focus on oncology and related disciplines. Their research spans a variety of topics and subfields, emphasizing genetics, pulmonary and respiratory medicine, epidemiology, endocrinology, diabetes and metabolism, and oncology.

Their main research topics include:

  • Glioma Diagnosis and Treatment
  • Meningioma and Schwannoma Management
  • Brain Metastases and Treatment
  • Pituitary Gland Disorders and Treatments
  • Radiation Therapy and Dosimetry
  • Advanced Radiotherapy Techniques
  • Pancreatic and Hepatic Oncology Research

Jay S. Loeffler has published in several prominent venues, with frequent contributions to:

  • International Journal of Radiation Oncology*Biology*Physics (12 publications)
  • Neuro-Oncology (3 publications)
  • Journal of the National Comprehensive Cancer Network (2 publications)
  • Nature Genetics (1 publication)
  • Nature Reviews Physics (1 publication)

Some of their recent papers include:

  • Central Nervous System Cancers, Version 3.2020, NCCN Clinical Practice Guidelines in Oncology (2020) - Journal of the National Comprehensive Cancer Network
  • Single-nucleus and spatial transcriptome profiling of pancreatic cancer identifies multicellular dynamics associated with neoadjuvant treatment (2022) - Nature Genetics
  • Physics and biomedical challenges of cancer therapy with accelerated heavy ions (2021) - Nature Reviews Physics
  • Phase 2 study of pembrolizumab in patients with recurrent and residual high-grade meningiomas (2022) - Nature Communications
  • Primary dural lymphomas: Clinical presentation, management, and outcome (2020) - Cancer

Frequent collaborators in their research include Helen A. Shih, Kevin Oh, Paul H. Chapman, William T. Curry, and Andrzej Niemierko.

Jay S. Loeffler's work is situated primarily within medicine, addressing critical challenges in cancer diagnosis, treatment, and therapy optimization, especially in the central nervous system and associated disorders.

In recognition of their contributions, Jay S. Loeffler was named a Fellow of the American Association for the Advancement of Science (AAAS) in 2014 and was elected a Member of the National Academy of Medicine (NAM) in 2011.

Best Publications

  • AZD2171, a Pan-VEGF Receptor Tyrosine Kinase Inhibitor, Normalizes Tumor Vasculature and Alleviates Edema in Glioblastoma Patients

    Tracy T. Batchelor;A. Gregory Sorensen;A. Gregory Sorensen;Emmanuelle di Tomaso;Wei Ting Zhang;Wei Ting Zhang

  • Single dose radiosurgical treatment of recurrent previously irradiated primary brain tumors and brain metastases: final report of RTOG protocol 90-05.

    Edward Shaw;Charles Scott;Luis Souhami;Robert Dinapoli

  • Angiogenesis in brain tumours

    Rakesh K. Jain;Emmanuelle di Tomaso;Dan G. Duda;Jay S. Loeffler

  • Lessons from phase III clinical trials on anti-VEGF therapy for cancer

    Rakesh K Jain;Dan G Duda;Jeffrey W Clark;Jay S Loeffler

  • Relative biological effectiveness (RBE) values for proton beam therapy.

    Harald Paganetti;Andrzej Niemierko;Marek Ancukiewicz;Leo E Gerweck

  • Charged particles in radiation oncology

    Marco Durante;Jay S. Loeffler

  • Insulin-like Growth Factor Receptor I Mediates Resistance to Anti-Epidermal Growth Factor Receptor Therapy in Primary Human Glioblastoma Cells through Continued Activation of Phosphoinositide 3-Kinase Signaling

    Arnab Chakravarti;Jay S Loeffler;Nicholas J Dyson

  • Stereotactic Radiosurgery for the Definitive, Noninvasive Treatment of Brain Metastases

    Eben Alexander;Thomas M. Moriarty;Roger B. Davis;Patrick Y. Wen

  • Cellular-Telephone Use and Brain Tumors

    Peter D. Inskip;Robert E. Tarone;Elizabeth E. Hatch;Timothy C. Wilcosky

  • Magnetic resonance image—directed stereotactic neurosurgery: use of image fusion with computerized tomography to enhance spatial accuracy

    E. Alexander;H. M. Kooy;M. Van Herk;M. Schwartz

  • A multiinstitutional outcome and prognostic factor analysis of radiosurgery for resectable single brain metastasis

    Richard M. Auchter;John P. Lamond;Eben Alexander;John M. Buatti

  • Biomarkers of response and resistance to antiangiogenic therapy.

    Rakesh K. Jain;Dan G. Duda;Christopher G. Willett;Dushyant V. Sahani

  • The role of stereotactic radiosurgery in the management of patients with newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline

    Mark E. Linskey;David W. Andrews;Anthony L. Asher;Stuart H. Burri

  • Phase II Trial of the Antiangiogenic Agent Thalidomide in Patients With Recurrent High-Grade Gliomas

    Howard A. Fine;William D. Figg;Kurt Jaeckle;Patrick Y. Wen

  • Tolerance of cranial nerves of the cavernous sinus to radiosurgery

    Roy B Tishler;Jay S Loeffler;L.Dade Lunsford;Christopher Duma

  • Phase II Study of Cediranib, an Oral Pan–Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor, in Patients With Recurrent Glioblastoma

    Tracy T. Batchelor;Dan G. Duda;Emmanuelle di Tomaso;Marek Ancukiewicz

  • The biology of brain metastases—translation to new therapies

    April F. Eichler;Euiheon Chung;David P. Kodack;Jay S. Loeffler

  • Quantitatively Determined Survivin Expression Levels Are of Prognostic Value in Human Gliomas

    Arnab Chakravarti;Elizabeth Noll;Peter McL. Black;Daniel F. Finkelstein

  • Primary CNS Lymphoma

    Tracy Batchelor;Jay S. Loeffler

  • Management of brain metastases.

    P Y Wen;J S Loeffler

Frequent Co-Authors

Eben Alexander
Eben Alexander Brigham and Women's Hospital
Peter McL. Black
Peter McL. Black University of British Columbia
Nancy J. Tarbell
Nancy J. Tarbell Harvard University
Patrick Y. Wen
Patrick Y. Wen Harvard University
Tracy T. Batchelor
Tracy T. Batchelor Brigham and Women's Hospital
Fred G. Barker
Fred G. Barker Harvard University
Howard A. Fine
Howard A. Fine Cornell University
Herman D. Suit
Herman D. Suit Harvard University
Douglas Kondziolka
Douglas Kondziolka New York University
Rakesh K. Jain
Rakesh K. Jain Harvard University

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