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Medicine

D-Index
133
Citations
79812
World Ranking
2198
National Ranking
1242

Overview

James C. Grotta is affiliated with The University of Texas Health Science Center at Houston in the United States. Their research primarily focuses on medicine, with specific expertise in epidemiology, neurology, internal medicine, rehabilitation, and pulmonary and respiratory medicine.

The scientific contributions of James C. Grotta include extensive work on acute ischemic stroke management, venous thromboembolism diagnosis and management, stroke rehabilitation and recovery, traumatic brain injury and neurovascular disturbances, cerebrovascular and carotid artery diseases, intracerebral and subarachnoid hemorrhage research, and intracranial aneurysms treatment and complications.

James C. Grotta has contributed to multiple recent papers, including:

  • Prospective, Multicenter, Controlled Trial of Mobile Stroke Units (2021) published in New England Journal of Medicine
  • Trial of Endovascular Thrombectomy for Large Ischemic Strokes (2023) published in New England Journal of Medicine
  • Standardized Nomenclature for Modified Rankin Scale Global Disability Outcomes: Consensus Recommendations From Stroke Therapy Academic Industry Roundtable XI (2021) published in Stroke
  • Top Priorities for Cerebroprotective Studies-A Paradigm Shift: Report From STAIR XI (2021) published in Stroke
  • Early Infarct Growth Rate Correlation With Endovascular Thrombectomy Clinical Outcomes (2020) published in Stroke

Frequent co-authors collaborating with James C. Grotta include:

  • Amrou Sarraj
  • Deep Pujara
  • Clark Sitton
  • Spiros Blackburn
  • Ameer E Hassan

James C. Grotta's work has been published extensively in several prominent venues, including:

  • Stroke
  • Stroke Vascular and Interventional Neurology
  • Neurology
  • Annals of Neurology
  • JAMA Neurology

Their research covers a broad spectrum of subfields, notably 159 publications in epidemiology, 105 in neurology, 59 in internal medicine, 54 in rehabilitation, and 42 in pulmonary and respiratory medicine. This multidisciplinary approach supports their focused topics in cerebrovascular diseases and stroke management.

Best Publications

  • Tissue plasminogen activator for acute ischemic stroke. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group.

    JC Grotta;M Kothari;Kma Welch

  • Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials

    Werner Hacke;Geoffrey Donnan;Cesare Fieschi;Markku Kaste

  • Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials

    Jonathan Emberson;Kennedy R Lees;Patrick Lyden;Lisa Blackwell

  • Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials.

    Kennedy R Lees;Erich Bluhmki;Rüdiger von Kummer;Thomas G Brott

  • Improved reliability of the NIH Stroke Scale using video training. NINDS TPA Stroke Study Group.

    Patrick Lyden;T. Brott;B. Tilley;K. M A Welch

  • Ultrasound-enhanced systemic thrombolysis for acute ischemic stroke.

    Andrei V. Alexandrov;Andrei V. Alexandrov;Carlos A. Molina;James C. Grotta;Zsolt Garami

  • Guidelines for the Management of Spontaneous Intracerebral Hemorrhage A Statement for Healthcare Professionals From a Special Writing Group of the Stroke Council, American Heart Association

    Joseph P. Broderick;Harold P. Adams;William Barsan;William Feinberg

  • Carotid Endarterectomy and Prevention of Cerebral Ischemia in Symptomatic Carotid Stenosis

    M R Mayberg;S E Wilson;F Yatsu;D G Weiss

  • Combined Intravenous and Intra-Arterial r-TPA Versus Intra-Arterial Therapy of Acute Ischemic Stroke Emergency Management of Stroke (EMS) Bridging Trial

    Christopher A. Lewandowski;Michael Frankel;Thomas A. Tomsick;Joseph Broderick

  • NXY-059 for the Treatment of Acute Ischemic Stroke

    Ashfaq Shuaib;Kennedy R. Lees;Patrick Lyden;James Grotta

  • NXY-059 for acute ischemic stroke

    Kennedy R. Lees;Justin A. Zivin;Tim Ashwood;Antonio Davalos

  • Scientific Rationale for the Inclusion and Exclusion Criteria for Intravenous Alteplase in Acute Ischemic Stroke: A Statement for Healthcare Professionals From the American Heart Association/American Stroke Association

    Bart M. Demaerschalk;Dawn O. Kleindorfer;Opeolu M. Adeoye;Andrew M. Demchuk

  • Arterial reocclusion in stroke patients treated with intravenous tissue plasminogen activator.

    Andrei V. Alexandrov;James C. Grotta

  • Mutations in Smooth Muscle Alpha-Actin (ACTA2) Cause Coronary Artery Disease, Stroke, and Moyamoya Disease, Along with Thoracic Aortic Disease

    Dong Chuan Guo;Christina L. Papke;Van Tran-Fadulu;Ellen S. Regalado

  • Rebleeding leads to poor outcome in ultra-early craniotomy for intracerebral hemorrhage

    Lewis B. Morgenstern;A. M. Demchuk;D. H. Kim;R. F. Frankowski

  • Reperfusion injury: demonstration of brain damage produced by reperfusion after transient focal ischemia in rats.

    Jaroslaw Aronowski;Roger Strong;James C. Grotta

  • Serum Glucose Level and Diabetes Predict Tissue Plasminogen Activator–Related Intracerebral Hemorrhage in Acute Ischemic Stroke

    Andrew M. Demchuk;Lewis B. Morgenstern;Derk W. Krieger;T. Linda Chi

  • Intravenous Thrombolysis Plus Hypothermia for Acute Treatment of Ischemic Stroke (ICTuS-L): Final Results

    Thomas M. Hemmen;Rema Raman;Kama Z. Guluma;Brett C. Meyer

  • Lack of Clinical Significance of Early Ischemic Changes on Computed Tomography in Acute Stroke

    Suresh C. Patel;Steven R. Levine;Barbara C. Tilley;James C. Grotta

  • Intravenous Tissue Plasminogen Activator for Acute Ischemic Stroke Feasibility, Safety, and Efficacy in the First Year of Clinical Practice

    David Chiu;Derk Krieger;Carlos Villar-Cordova;Scott E. Kasner

Frequent Co-Authors

Sean I Savitz
Sean I Savitz The University of Texas Health Science Center at Houston
Andrei V. Alexandrov
Andrei V. Alexandrov University of Tennessee Health Science Center
Patrick D. Lyden
Patrick D. Lyden University of Southern California
Andrew M. Demchuk
Andrew M. Demchuk University of Calgary
Lewis B. Morgenstern
Lewis B. Morgenstern University of Michigan–Ann Arbor
Gregory W. Albers
Gregory W. Albers Stanford University
Werner Hacke
Werner Hacke Heidelberg University
Kennedy R. Lees
Kennedy R. Lees University of Glasgow
David S. Liebeskind
David S. Liebeskind University of California, Los Angeles
Jeffrey L Saver
Jeffrey L Saver University of California, Los Angeles

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