J D Capra

Research.com Recognitions

• 1993 - AAI Distinguished Service Award, American Association of Immunologists For service as AAI Program Committee Chair
• 1991 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Best Publications

• Rapid cloning of high-affinity human monoclonal antibodies against influenza virus

  Jens Wrammert;Kenneth Smith;Joe Miller;William A. Langley

  1268
  Citations

• Human CD14 mediates recognition and phagocytosis of apoptotic cells

  Andrew Devitt;Andrew Devitt;Odette D. Moffatt;Odette D. Moffatt;Chandra Raykundalia;J. Donald Capra

  868
  Citations

• Analysis of somatic mutation in five B cell subsets of human tonsil.

  V. Pascual;Yong-Jun Liu;A. Magalski;O. De Bouteiller

  786
  Citations

• Rapid generation of fully human monoclonal antibodies specific to a vaccinating antigen

  Kenneth Smith;Lori Garman;Jens Wrammert;Nai-Ying Zheng

  572
  Citations

• Analysis of HLA-DQ genotypes and susceptibility in insulin-dependent diabetes mellitus

  J M Baisch;T Weeks;R Giles;M Hoover

  464
  Citations

• Initial characterization of monoclonal antibodies against human monocytes

  V. Ugolini;G. Nunez;R. G. Smith;P. Stastny

  381
  Citations

• Neisseria gonorrhoeae and neisseria meningitidis: extracellular enzyme cleaves human immunoglobulin A.

  Plaut Ag;Gilbert Jv;Artenstein Ms;Capra Jd

  369
  Citations

• Studies on the clonal origin of multiple myeloma. Use of individually specific (idiotype) antibodies to trace the oncogenic event to its earliest point of expression in B-cell differentiation.

  H. Kubagawa;Larry Vogler;J.D. Capra;M.E. Conrad

  335
  Citations

• Somatic Hypermutation Introduces Insertions and Deletions into Immunoglobulin V Genes

  Patrick C. Wilson;Odette de Bouteiller;Yong-Jun Liu;Kathleen Potter

  334
  Citations

• Antigenic specificities related to the cold agglutinin activity of gamma M globulins.

  Ralph C. Williams;Henry G. Kunkel;J. Donald Capra

  307
  Citations

• VH restriction among human cold agglutinins. The VH4-21 gene segment is required to encode anti-I and anti-i specificities.

  V Pascual;K Victor;M Spellerberg;T J Hamblin

  290
  Citations

• Nucleotide sequence analysis of the V regions of two IgM cold agglutinins. Evidence that the VH4-21 gene segment is responsible for the major cross-reactive idiotype.

  V Pascual;K Victor;D Lelsz;M B Spellerberg

  284
  Citations

• The smaller human VH gene families display remarkably little polymorphism.

  Inaki Sanz;P. Kelly;C. Williams;S. Scholl

  280
  Citations

• Nucleotide sequences of eight human natural autoantibody VH regions reveals apparent restricted use of VH families.

  I Sanz;P Casali;J W Thomas;A L Notkins

  269
  Citations

• A new human immunoglobulin VH family preferentially rearranged in immature B-cell tumours.

  C. G. Humphries;A. Shen;W. A. Kuziel;J. D. Capra

  247
  Citations

• The complete nucleotide sequences of the heavy chain variable regions of six monospecific rheumatoid factors derived from Epstein-Barr virus-transformed B cells isolated from the synovial tissue of patients with rheumatoid arthritis. Further evidence that some autoantibodies are unmutated copies of germ line genes.

  V. Pascual;I. Randen;K. Thompson;Mouldi Sioud

  238
  Citations

• High-level production of a functional immunoglobulin heterodimer in a baculovirus expression system.

  C A Hasemann;J D Capra

  221
  Citations

• Human immunoglobulin heavy-chain minilocus recombination in transgenic mice: gene-segment use in mu and gamma transcripts.

  N Tuaillon;L D Taylor;N Lonberg;P W Tucker

  208
  Citations

• SIMILARITIES IN THE LIGHT CHAINS OF ANTI-γ-GLOBULINS SHOWING CROSS-IDIOTYPIC SPECIFICITIES

  H. G. Kunkel;R. J. Winchester;F. G. Joslin;J. D. Capra

  200
  Citations

• Induction of Somatic Mutation in a Human B Cell Line In Vitro

  Stéphane Denépoux;Diane Razanajaona;Dominique Blanchard;Geneviève Meffre

  199
  Citations

• Receptor Revision of Immunoglobulin Heavy Chain Variable Region Genes in Normal Human B Lymphocytes

  Patrick C. Wilson;Patrick C. Wilson;Kenneth Wilson;Yong-Jun Liu;Jacques Banchereau

  194
  Citations

• VH4-21, a human VH gene segment overrepresented in the autoimmune repertoire.

  V Pascual;J D Capra

  189
  Citations

• VH sequence of a human anti-Sm autoantibody. Evidence that autoantibodies can be unmutated copies of germline genes.

  I Sanz;H Dang;M Takei;N Talal

  185
  Citations

• Clonally related IgM rheumatoid factors undergo affinity maturation in the rheumatoid synovial tissue.

  I Randen;D Brown;K M Thompson;N Hughes-Jones

  183
  Citations

• Peptide recognition, T cell receptor usage and HLA restriction elements of human heat-shock protein (hsp) 60 and mycobacterial 65-kDa hsp-reactive T cell clones from rheumatoid synovial fluid

  Alison J. Quayle;Kay Black Wilson;Shu Guang Li;Jens Kjeldsen-Kragh

  174
  Citations

• A human Ro/SS-A autoantigen is the homologue of calreticulin and is highly homologous with onchocercal RAL-1 antigen and an aplysia "memory molecule".

  D P McCauliffe;E Zappi;T S Lieu;M Michalak

  165
  Citations

• Structural analysis of a human I-A homologue using a monoclonal antibody that recognizes an MB3-like specificity.

  R C Giles;G Nunez;C K Hurley;A Nunez-Roldan;A Nunez-Roldan

  161
  Citations

• Rheumatoid factors isolated from patients with autoimmune disorders are derived from germline genes distinct from those encoding the Wa, Po, and Bla cross-reactive idiotypes.

  K. D. Victor;I. Randen;K. Thompson;O. Forre

  144
  Citations

• The human HLA-DR antigens are encoded by multiple beta-chain loci.

  C K Hurley;G Nunez;R Winchester;O J Finn

  116
  Citations

• Nucleotide sequence analysis of rheumatoid factors and polyreactive antibodies derived from patients with rheumatoid arthritis reveals diverse use of VH and VL gene segments and extensive variability in CDR-3.

  V Pascual;K Victor;I Randen;K Thompson

  113
  Citations