World's Best Scientists 2026 revealed!

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Immunology

D-Index
75
Citations
22701
World Ranking
1972
National Ranking
17

Research.com Recognitions

  • 2019 - Fellow, The World Academy of Sciences

Overview

Hualan Chen is affiliated with the Harbin Veterinary Research Institute in China, focusing on research at the intersection of veterinary science and infectious diseases. Their work spans multiple specialties within medicine and agricultural and biological sciences, with a predominant emphasis on influenza virus research and animal disease management.

The scientist has contributed extensively to fields including epidemiology, agronomy and crop science, infectious diseases, immunology, and molecular biology. These areas reflect a multidisciplinary approach combining disease tracking, immune response investigation, and broader biological impacts.

Key topics in Chen's research include:

  • Influenza Virus Research Studies
  • Animal Disease Management and Epidemiology
  • Viral Gastroenteritis Research and Epidemiology
  • Respiratory Viral Infections Research
  • Interferon and Immune Responses
  • Animal Virus Infections Studies
  • Immune Response and Inflammation

Chen's recent publications demonstrate a focus on influenza and coronavirus infections, addressing both viral characterization and host interactions. Important papers include:

  • "Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS-coronavirus 2" (2020, Science)
  • "Alarming situation of emerging H5 and H7 avian influenza and effective control strategies" (2022, Emerging Microbes & Infections)
  • "Global dissemination of H5N1 influenza viruses bearing the clade 2.3.4.4b HA gene and biologic analysis of the ones detected in China" (2022, Emerging Microbes & Infections)
  • "The PB1 protein of influenza A virus inhibits the innate immune response by targeting MAVS for NBR1-mediated selective autophagic degradation" (2021, PLoS Pathogens)
  • "Novel H5N6 reassortants bearing the clade 2.3.4.4b HA gene of H5N8 virus have been detected in poultry and caused multiple human infections in China" (2022, Emerging Microbes & Infections)

The venues where Chen frequently publishes illustrate the scientist's research dissemination platforms, including:

  • Emerging Microbes & Infections
  • PLoS Pathogens
  • Viruses
  • Science China Life Sciences
  • Journal of Virology

Several frequent coauthors collaborate with Chen, reflecting recurring research partnerships:

  • Jianzhong Shi
  • Guohua Deng
  • Xianying Zeng
  • Chengjun Li
  • Guobin Tian

Chen has also received recognition as a Fellow of The World Academy of Sciences, awarded in 2019. This distinction aligns with their extensive contributions in the study of viral diseases impacting both humans and animals.

Best Publications

  • Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS-coronavirus 2.

    Jianzhong Shi;Zhiyuan Wen;Gongxun Zhong;Huanliang Yang

  • Molecular Basis of Replication of Duck H5N1 Influenza Viruses in a Mammalian Mouse Model

    Zejun Li;Hualan Chen;Peirong Jiao;Guohua Deng

  • Role of domestic ducks in the propagation and biological evolution of highly pathogenic H5N1 influenza viruses in Asia

    D. J. Hulse-Post;K. M. Sturm-Ramirez;J. Humberd;P. Seiler

  • Are Ducks Contributing to the Endemicity of Highly Pathogenic H5N1 Influenza Virus in Asia

    K. M. Sturm-Ramirez;D. J. Hulse-Post;E. A. Govorkova;J. Humberd

  • A Single-Amino-Acid Substitution in the NS1 Protein Changes the Pathogenicity of H5N1 Avian Influenza Viruses in Mice

    Peirong Jiao;Guobin Tian;Yanbing Li;Guohua Deng

  • H7N9 Influenza Viruses Are Transmissible in Ferrets by Respiratory Droplet

    Qianyi Zhang;Qianyi Zhang;Jianzhong Shi;Guohua Deng;Jing Guo

  • Evolution of H9N2 influenza viruses from domestic poultry in Mainland China

    Chengjun Li;Kangzhen Yu;Guobin Tian;Dandan Yu

  • Identification of amino acids in HA and PB2 critical for the transmission of H5N1 avian influenza viruses in a mammalian host.

    Yuwei Gao;Ying Zhang;Kyoko Shinya;Guohua Deng

  • Properties and dissemination of H5N1 viruses isolated during an influenza outbreak in migratory waterfowl in western China

    Hualan Chen;Yanbing Li;Zejun Li;Jianzhong Shi

  • Honeysuckle-encoded atypical microRNA2911 directly targets influenza A viruses

    Zhen Zhou;Xihan Li;Jinxiong Liu;Lei Dong

  • Role for migratory wild birds in the global spread of avian influenza H5N8

    S.J. Lycett;R. Bodewes;Anne Pohlmann

  • Lack of transmission of H5N1 avian–human reassortant influenza viruses in a ferret model

    Taronna R. Maines;Li-Mei Chen;Yumiko Matsuoka;Hualan Chen

  • The duck genome and transcriptome provide insight into an avian influenza virus reservoir species

    Yinhua Huang;Yinhua Huang;Yingrui Li;David W Burt;Hualan Chen

  • The NS1 Gene Contributes to the Virulence of H5N1 Avian Influenza Viruses

    Zejun Li;Yongping Jiang;Peirong Jiao;Aiqin Wang

  • Evaluation of a Genetically Modified Reassortant H5N1 Influenza A Virus Vaccine Candidate Generated by Plasmid-Based Reverse Genetics

    Kanta Subbarao;Hualan Chen;David Swayne;Louise Mingay

  • Newcastle Disease Virus-Based Live Attenuated Vaccine Completely Protects Chickens and Mice from Lethal Challenge of Homologous and Heterologous H5N1 Avian Influenza Viruses

    Jinying Ge;Guohua Deng;Zhiyuan Wen;Guobing Tian

  • Review of influenza A virus in swine worldwide: a call for increased surveillance and research.

    A. Vincent;L. Awada;I. Brown;H. Chen

  • Protective efficacy in chickens, geese and ducks of an H5N1-inactivated vaccine developed by reverse genetics.

    Guobin Tian;Suhua Zhang;Yanbing Li;Zhigao Bu

  • Two amino acid residues in the matrix protein M1 contribute to the virulence difference of H5N1 avian influenza viruses in mice.

    Shufang Fan;Guohua Deng;Jiasheng Song;Guobin Tian

  • H5N1 influenza viruses: outbreaks and biological properties

    Gabriele Neumann;Hualan Chen;George F Gao;Yuelong Shu

Frequent Co-Authors

Zhigao Bu
Zhigao Bu Harbin Veterinary Research Institute
Yoshihiro Kawaoka
Yoshihiro Kawaoka University of Tokyo
Chengjun Li
Chengjun Li Harbin Veterinary Research Institute
Yasuo Suzuki
Yasuo Suzuki Chubu University
Nancy J. Cox
Nancy J. Cox Vanderbilt University Medical Center
Yi Guan
Yi Guan University of Hong Kong
Kanta Subbarao
Kanta Subbarao University of Melbourne
David E. Swayne
David E. Swayne United States Department of Agriculture
Jacqueline M. Katz
Jacqueline M. Katz Emory University
Richard J. Webby
Richard J. Webby St. Jude Children's Research Hospital

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