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Holger Luthman

Holger Luthman

D-Index & Metrics

Biology and Biochemistry

D-Index
51
Citations
9248
World Ranking
17180
National Ranking
271

Overview

Holger Luthman is affiliated with Lund University in Sweden and focuses research efforts primarily within the fields of Biochemistry, Genetics and Molecular Biology. Their work spans several subfields, notably Molecular Biology and Genetics.

The main research topics covered in their publications include:

  • Epigenetics and DNA Methylation
  • Genetic Syndromes and Imprinting
  • Cancer-related gene regulation

Luthman's recent published work includes the paper titled Epigenome-wide cross-tissue correlation of human bone and blood DNA methylation - can blood be used as a surrogate for bone? published in 2020 in the journal Epigenetics. This study addresses the relationship between DNA methylation patterns in bone and blood, investigating the potential for blood to serve as a proxy in epigenetic analyses of bone tissue.

Collaborations form a part of their research practice, with frequent co-authors including Parvaneh Ebrahimi, Fiona E. McGuigan, and Kristina Åkesson.

Luthman's work has been published in relevant venues focusing on epigenetic research, with the journal Epigenetics documented as a frequent publication outlet.

Best Publications

  • High efficiency polyoma DNA transfection of chloroquine treated cells

    Holger Luthman;Goran Magnusson

  • Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion

    Charlotte Ling;S Del Guerra;R Lupi;Tina Rönn

  • Mutational spectrum of the steroid 21-hydroxylase gene in Sweden: implications for genetic diagnosis and association with disease manifestation.

    A Wedell;A Thilén;E M Ritzén;B Stengler

  • MHC2TA is associated with differential MHC molecule expression and susceptibility to rheumatoid arthritis, multiple sclerosis and myocardial infarction

    Maria Swanberg;Olle Lidman;Leonid Padyukov;Per Eriksson

  • Genetic analysis of non-insulin dependent diabetes mellitus in the GK rat.

    Joakim Galli;Luo-Sheng Li;Anna Glaser;Claes-Göran Östenson

  • Overexpression of Alpha2A-Adrenergic Receptors Contributes to Type 2 Diabetes

    Anders H. Rosengren;Ramunas Jokubka;Damon Tojjar;Charlotte Granhall

  • Glucokinase mutations associated with non-insulin-dependent (type 2) diabetes mellitus have decreased enzymatic activity: implications for structure/function relationships.

    M. Gidh-Jain;J. Takeda;L. Z. Xu;A. J. Lange

  • Steroid 21-hydroxylase deficiency: two additional mutations in salt-wasting disease and rapid screening of disease-causing mutations

    Anna Wedell;Holger Luthman

  • Steroid 21-hydroxylase deficiency: three additional mutated alleles and establishment of phenotype-genotype relationships of common mutations.

    A Wedell;E M Ritzén;B Haglund-Stengler;H Luthman

  • Insulin-degrading enzyme identified as a candidate diabetes susceptibility gene in GK rats.

    Hossein Fakhrai-Rad;Andrej Nikoshkov;Ashraf Kamel;Maria Fernström

  • High diagnostic accuracy for idiopathic Addison’s disease with a sensitive radiobinding assay for autoantibodies against recombinant human 21-hydroxylase

    A Falorni;A Nikoshkov;S Laureti;E Grenbäck

  • Identification of rat susceptibility loci for adjuvant-oil-induced arthritis

    Johnny C. Lorentzen;Anna Glaser;Lena Jacobsson;Joakim Galli

  • Susceptibility loci for atopic dermatitis on chromosomes 3, 13, 15, 17 and 18 in a Swedish population

    M. Bradley;C. Söderhäll;H. Luthman;C.-F. Wahlgren

  • Multilevel regulation of low-density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression in normal and leukemic cells

    Sigurd Vitols;Svante Norgren;Gunnar Juliusson;Loukas Tatidis

  • Phenotypic characterization of the Trp64Arg polymorphism in the beta 3-adrenergic receptor gene in normal weight and obese subjects.

    Li Ls;Lönnqvist F;Luthman H;Arner P

  • Quantitative trait loci disposing for both experimental arthritis and encephalomyelitis in the DA rat; impact on severity of myelin oligodendrocyte glycoprotein‐induced experimental autoimmune encephalomyelitis and antibody isotype pattern

    Ingrid Dahlman;Johnny C. Lorentzen;Katrien L. de Graaf;Andreas Stefferl

  • 21-hydroxylase autoantibodies in adult patients with endocrine autoimmune diseases are highly specific for Addison's disease

    A Falorni;S Laureti;A Nikoshkov;M L Picchio

  • Non-contiguous segments of the polyoma genome required in cis for DNA replication.

    Holger Luthman;Maj-Greth Nilsson;Göran Magnusson

  • Increased renal arterial resistance predicts the course of renal function in type 2 diabetes with microalbuminuria.

    Romano Nosadini;Mario Velussi;Enrico Brocco;Cataldo Abaterusso

  • Mutational Spectrum of the Steroid 21-Hydroxylase Gene In Sweden: Implications for Genetic Diagnosis and Association With Disease Manifestation

    Anna Wedell;Astrid Thilén;E. Martin Ritzén;Barhro Stengler

Frequent Co-Authors

Ingrid Kockum
Ingrid Kockum Karolinska Institute
Anna Wedell
Anna Wedell Karolinska University Hospital
Leif Groop
Leif Groop Lund University
Valeriya Lyssenko
Valeriya Lyssenko University of Bergen
Suad Efendic
Suad Efendic Karolinska Institute
Åke Lernmark
Åke Lernmark Lund University
Ingrid Dahlman
Ingrid Dahlman Karolinska Institute
Catharina Larsson
Catharina Larsson Karolinska University Hospital
Flemming Pociot
Flemming Pociot Steno Diabetes Center
Magnus Nordenskjöld
Magnus Nordenskjöld Karolinska Institute

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