World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
46
Citations
6816
World Ranking
6763
National Ranking
526

Overview

James B. Uney is affiliated with the University of Bristol in the United Kingdom. Their research spans multiple disciplines, primarily focused in Medicine, Biochemistry, Genetics and Molecular Biology, and Neuroscience. The scientist has contributed notably to subfields such as Cellular and Molecular Neuroscience, Molecular Biology, Physiology, Epidemiology, and Genetics.

Their work covers several key topics, including:

  • Alzheimer's disease research and treatments
  • Nuclear Receptors and Signaling
  • Autophagy in Disease and Therapy
  • Neuroscience and Neuropharmacology Research
  • Genetics and Neurodevelopmental Disorders
  • Memory and Neural Mechanisms
  • Mitochondrial Function and Pathology

James B. Uney has published in various scientific journals with multiple papers appearing in the Journal of Biological Chemistry. Other frequent publication venues include Learning & Memory, Scientific Reports, Brain Pathology, and Frontiers in Molecular Neuroscience.

Notable recent papers include:

  • "A dual druggable genome-wide siRNA and compound library screening approach identifies modulators of parkin recruitment to mitochondria", 2020, Journal of Biological Chemistry
  • "CREB transcription in the medial prefrontal cortex regulates the formation of long-term associative recognition memory", 2020, Learning & Memory
  • "AZD5438 a GSK-3a/b and CDK inhibitor is antiapoptotic modulates mitochondrial activity and protects human neurons from mitochondrial toxins", 2023, Scientific Reports
  • "Abnormal scaffold attachment factor 1 expression and localization in spinocerebellar ataxias and Huntington's chorea", 2020, Brain Pathology
  • "The miRNA transcriptome of cerebrospinal fluid in preterm infants reveals the signaling pathways that promote reactive gliosis following cerebral hemorrhage", 2023, Frontiers in Molecular Neuroscience

The scientist frequently collaborates with colleagues such as Helen L. Scott, Gongyu Shi, Liang-Fong Wong, Nicola Buckner, and Nicholas D. Allen, indicating a strong network focused on diverse biomedical research topics.

Best Publications

  • Surface Expression of AMPA Receptors in Hippocampal Neurons Is Regulated by an NSF-Dependent Mechanism

    Jacques Noel;G.Scott Ralph;Lisa Pickard;Jackie Williams

  • Gene transfer of the JNK interacting protein-1 protects dopaminergic neurons in the MPTP model of Parkinson's disease

    Xu Gang Xia;Thomas Harding;Michael Weller;Alison Bieneman

  • Removal of AMPA receptors (AMPARs) from synapses is preceded by transient endocytosis of extrasynaptic AMPARs.

    Michael C. Ashby;Sarah A. De La Rue;G. Scott Ralph;James Uney

  • Axotomy-Induced miR-21 Promotes Axon Growth in Adult Dorsal Root Ganglion Neurons

    Iain T. Strickland;Louise Richards;Fiona E. Holmes;David Wynick

  • Expression of miR-1, miR-133a, miR-133b and miR-206 increases during development of human skeletal muscle.

    Andrie Koutsoulidou;Nikolaos P Mastroyiannopoulos;Denis Furling;James B Uney

  • RNA interference and the use of small interfering RNA to study gene function in mammalian systems

    I Bantounas;LA Phylactou;James B Uney

  • Expression of long-term depression underlies visual recognition memory

    Sarah Griffiths;Helen Scott;Colin Glover;Colin Glover;Alison Bienemann

  • Adenoviral-mediated, high-level, cell-specific transgene expression: a SYN1-WPRE cassette mediates increased transgene expression with no loss of neuron specificity.

    Colin P.J. Glover;Alison S. Bienemann;Darren J. Heywood;A.Siobhan Cosgrave

  • Switching transgene expression in the brain using an adenoviral tetracycline-regulatable system.

    Thomas C. Harding;Brad J. Geddes;David Murphy;David Knight

  • Human mesenchymal stem cells abrogate experimental allergic encephalomyelitis after intraperitoneal injection, and with sparse CNS infiltration.

    David Gordon;Gordana Pavlovska;Colin P. Glover;James B. Uney

  • Inhibition of JNK by Overexpression of the JNK Binding Domain of JIP-1 Prevents Apoptosis in Sympathetic Neurons

    Thomas C. Harding;Luzheng Xue;Ali Bienemann;Darren Haywood

  • Loss of MicroRNA-7 Regulation Leads to α-Synuclein Accumulation and Dopaminergic Neuronal Loss In Vivo.

    Kirsty J McMillan;Tracey K Murray;Nora Bengoa-Vergniory;Oscar Cordero-Llana

  • Hsp40 Molecules That Target to the Ubiquitin-proteasome System Decrease Inclusion Formation in Models of Polyglutamine Disease

    J L Howarth;S Kelly;M P Keasey;C P J Glover

  • Separate elements of episodic memory subserved by distinct hippocampal-prefrontal connections

    Gareth R I Barker;Paul J Banks;Hannah Scott;G Scott Ralph

  • MicroRNA‐132 regulates recognition memory and synaptic plasticity in the perirhinal cortex

    Helen L Scott;Francesco Tamagnini;Francesco Tamagnini;Katherine E Narduzzo;Joanna L Howarth

  • Human mesenchymal stem cells infiltrate the spinal cord, reduce demyelination, and localize to white matter lesions in experimental autoimmune encephalomyelitis.

    David Gordon;Gordana Pavlovska;James B. Uney;David C. Wraith

  • Tissue inhibitor of metalloproteinase 1 inhibits excitotoxic cell death in neurons.

    Hiang Khoon Tan;Darren Heywood;G.Scott Ralph;Alison Bienemann

  • Prolyl oligopeptidase binds to GAP-43 and functions without its peptidase activity.

    E Di Daniel;CP Glover;CP Glover;E Grot;MK Chan

  • Differential Internalization of Mammalian and Non-mammalian Gonadotropin-releasing Hormone Receptors: UNCOUPLING OF DYNAMIN-DEPENDENT INTERNALIZATION FROM MITOGEN-ACTIVATED PROTEIN KINASE SIGNALING *

    James N. Hislop;Helen M. Everest;Andrea Flynn;Tom Harding

  • Long-term gene therapy in the CNS: Reversal of hypothalamic diabetes insipidus in the Brattleboro rat by using an adenovirus expressing arginine vasopressin

    Brad J. Geddes;Tom C. Harding;Stafford L. Lightman;James B. Uney

  • cAMP Responsive Element-Binding Protein Phosphorylation Is Necessary for Perirhinal Long-Term Potentiation and Recognition Memory

    E. Clea Warburton;Colin P. J. Glover;Peter V. Massey;Humin Wan

Frequent Co-Authors

Jeremy M. Henley
Jeremy M. Henley University of Bristol
Graham L. Collingridge
Graham L. Collingridge Lunenfeld-Tanenbaum Research Institute
Elek Molnar
Elek Molnar University of Bristol
Zafar I. Bashir
Zafar I. Bashir University of Bristol
Malcolm W. Brown
Malcolm W. Brown University of Bristol
Michael J. O'Neill
Michael J. O'Neill Eli Lilly (United States)
Richard Wade-Martins
Richard Wade-Martins University of Oxford
Sergey Kasparov
Sergey Kasparov University of Bristol
Beverly L. Davidson
Beverly L. Davidson Children's Hospital of Philadelphia
Frederik Claeyssens
Frederik Claeyssens University of Sheffield

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