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Pekka T. Männistö

Pekka T. Männistö

University of Helsinki
Finland

D-Index & Metrics

Chemistry

D-Index
55
Citations
11358
World Ranking
12081
National Ranking
70

Pekka T. Männistö publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Pekka T. Männistö sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 335 publications — 70th percentile

70% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

Pekka T. Männistö D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Pekka T. Männistö sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 55 D-Index — 33rd percentile

33% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Overview

Pekka T. Männistö is affiliated with the University of Helsinki in Finland. Their research primarily focuses on medicine, with particular attention to neurology and cognitive neuroscience as well as molecular biology. Their work involves the study of enzyme function and inhibition, neurological disorders and treatments, including Parkinson's Disease mechanisms and treatments, and autism spectrum disorder research.

Among the recent papers authored by Pekka T. Männistö are:

  • The Catechol O-Methyltransferase Inhibitor Entacapone in the Treatment of Parkinson's Disease: Personal Reflections on a First-in-Class Drug Development Programme 40 Years On (2024, Neurology and Therapy)
  • COMT gene locus: new functional variants (2020, UNC Libraries)
  • Epistasis between polymorphisms in COMT, ESR1, and GCH1 influences COMT enzyme activity and pain (2020, UNC Libraries)

Frequent coauthors include:

  • Shad B. Smith
  • William Maixner
  • Ilkka Reenilä
  • Luda Diatchenko
  • Tapani Keränen

Publication venues that commonly feature their work are:

  • UNC Libraries
  • Neurology and Therapy

The research scope of Pekka T. Männistö covers topics including:

  • Parkinson's Disease Mechanisms and Treatments
  • Neurological disorders and treatments
  • Autism Spectrum Disorder Research
  • Enzyme function and inhibition

Best Publications

  • Catechol-O-methyltransferase (COMT): biochemistry, molecular biology, pharmacology, and clinical efficacy of the new selective COMT inhibitors.

    Pekka T. Männistö;Seppo Kaakkola

  • Neurotransmitter regulation of anterior pituitary hormones.

    J Tuomisto;P Männistö

  • Pharmacologically Diverse Antidepressants Rapidly Activate Brain-Derived Neurotrophic Factor Receptor TrkB and Induce Phospholipase-Cγ Signaling Pathways in Mouse Brain

    Tomi Rantamäki;Panu Hendolin;Aino Kankaanpää;Jelena Mijatovic

  • Site-specific role of catechol-O-methyltransferase in dopamine overflow within prefrontal cortex and dorsal striatum.

    Leonid Yavich;Markus M. Forsberg;Maria Karayiorgou;Joseph A. Gogos

  • On the role of prolyl oligopeptidase in health and disease.

    J.A. García-Horsman;P.T. Männistö;P.T. Männistö;J.I. Venäläinen

  • Characteristics of catechol O-methyltransferase (COMT) and properties of selective COMT inhibitors

    P. T. Männistö;I. Ulmanen;K. Lundström;J. Taskinen

  • Brain catecholamine metabolism in catechol-O-methyltransferase (COMT)-deficient mice.

    Marko Huotari;Joseph A. Gogos;Maria Karayiorgou;Olli Koponen

  • Quantitative role of COMT in dopamine clearance in the prefrontal cortex of freely moving mice

    Mikko Käenmäki;Anne Emilia Tammimäki;Timo Tapio Myöhänen;Kaisa Pakarinen

  • Synthesis of some novel potent and selective catechol O-methyltransferase inhibitors.

    Reijo Backstrom;Erkki Honkanen;Aino Pippuri;Pekka Kairisalo

  • The multiple faces of quercetin in neuroprotection.

    Bernardino Ossola;Tiina M Kääriäinen;Pekka T Männistö

  • Amantadine protects dopamine neurons by a dual action: Reducing activation of microglia and inducing expression of GNDF in astroglia

    Bernardino Ossola;Nadia Schendzielorz;Shih-Heng Chen;Gary S. Bird

  • Catechol-O-methyltransferase gene polymorphism and chronic human pain: a systematic review and meta-analysis

    Anne Tammimäki;Pekka T. Männistö

  • Rationale for Selective COMT Inhibitors as Adjuncts in the Drug Treatment of Parkinson's Disease

    P. T. Männistö;S. Kaakkola

  • General properties and clinical possibilities of new selective inhibitors of catechol O-methyltransferase.

    Seppo Kaakkola;Ariel Gordin;Pekka T. Männistö

  • Chronic infusion of CDNF prevents 6-OHDA-induced deficits in a rat model of Parkinson's disease.

    Merja H. Voutilainen;Susanne Bäck;Johan Peränen;Päivi Lindholm

  • Pharmacologically active compounds, methods for the preparation thereof and compositions containing the same

    Reijo J. Backstrom;Kalevi E. Heinola;Erkki J. Honkanen;Seppo K. Kaakkola

  • 7-Nitroindazole, a nitric oxide synthase inhibitor, has anxiolytic-like properties in exploratory models of anxiety.

    Vallo Volke;Andres Soosaar;Sulev Kõks;Michel Bourin

  • New selective COMT inhibitors: useful adjuncts for Parkinson's disease?

    P.T. Männistö;S. Kaakkola

  • Inhibition of catechol-O-methyltransferase activity by two novel disubstituted catechols in the rat

    Erkki Nissinen;Inge-Britt Lindén;Eija Schultz;Seppo Kaakkola

  • Distribution of catechol-O-methyltransferase (COMT) proteins and enzymatic activities in wild-type and soluble COMT deficient mice

    Timo Tapio Myöhänen;Nadia Schendzielorz;Pekka Männistö

  • Evolutionary relationships of the prolyl oligopeptidase family enzymes.

    Jarkko I. Venäläinen;Risto O. Juvonen;Pekka T. Männistö

  • Activation of 5-HT2A receptors impairs response control of rats in a five-choice serial reaction time task

    Tiina Koskinen;Sirja Ruotsalainen;Tarja Puumala;Raimo Lappalainen

  • Different in vivo properties of three new inhibitors of catechol O-methyltransferase in the rat.

    Pekka T. Männistö;Päivi Tuomainen;Raimo K. Tuominen

  • A prolyl oligopeptidase inhibitor, KYP-2047, reduces α-synuclein protein levels and aggregates in cellular and animal models of Parkinson's disease.

    T T Myöhänen;T T Myöhänen;M J Hannula;R Van Elzen;Melanie Gérard

  • Comparative pharmacokinetics of metronidazole and tinidazole as influenced by administration route.

    J Mattila;P T Männistö;R Mäntylä;S Nykänen

  • Amantadine protects dopamine neurons by a dual action: Reducing activation of microglia and inducing expression of GNDF in astroglia

    Bernardino Ossola;Nadia Schendzielorz;Nadia Schendzielorz;Shih-Heng Chen;Gary S. Bird

Frequent Co-Authors

Eero Vasar
Eero Vasar University of Tartu
Jouko Tuomisto
Jouko Tuomisto Finnish Institute for Health and Welfare (THL)
Sulev Kõks
Sulev Kõks Perron Institute for Neurological and Translational Science
Mart Saarma
Mart Saarma University of Helsinki
Jaanus Harro
Jaanus Harro University of Tartu
Tomasz Róg
Tomasz Róg University of Helsinki
Mikko Karttunen
Mikko Karttunen University of Western Ontario
Markku Mäki
Markku Mäki Tampere University
Katri Kaukinen
Katri Kaukinen Tampere University
Tomi Järvinen
Tomi Järvinen University of Eastern Finland

External Links

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Best Scientists Citing Pekka T. Männistö

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Publications: 49

Philip Seeman

Philip Seeman

University of Toronto

Publications: 47

Eero Castrén

Eero Castrén

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Publications: 46

Daniel R. Weinberger

Daniel R. Weinberger

Johns Hopkins University

Publications: 44

Mart Saarma

Mart Saarma

University of Helsinki

Publications: 41

Jouko Tuomisto

Jouko Tuomisto

Finnish Institute for Health and Welfare (THL)

Publications: 34

Pertti Panula

Pertti Panula

University of Helsinki

Publications: 30

Eero Vasar

Eero Vasar

University of Tartu

Publications: 28

Ercole L. Cavalieri

Ercole L. Cavalieri

University of Nebraska Medical Center

Publications: 27

Luda Diatchenko

Luda Diatchenko

McGill University

Publications: 23

Jaanus Harro

Jaanus Harro

University of Tartu

Publications: 21

Trevor W. Robbins

Trevor W. Robbins

University of Cambridge

Publications: 21

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Mikko Airavaara

University of Helsinki

Publications: 21

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Anne-Marie Lambeir

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Publications: 21

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David Goldman

National Institutes of Health

Publications: 20

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University of Barcelona

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