World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
61
Citations
15394
World Ranking
2971
National Ranking
223

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Enzyme

Hans-Martin Jäck mostly deals with Molecular biology, B cell, Cell biology, B-cell receptor and Flow cytometry. As part of one scientific family, he deals mainly with the area of Molecular biology, narrowing it down to issues related to the T cell, and often CD40. The various areas that Hans-Martin Jäck examines in his B cell study include Cell culture, Naive B cell and Signal transduction.

His studies in Cell biology integrate themes in fields like Histone H2A and Intratubular germ cell neoplasia, Germ line development, Gonocyte, Germ cell. The concepts of his B-cell receptor study are interwoven with issues in Stromal cell, Cellular differentiation, Golgi apparatus, Receptor and Intracellular. His study in the field of Cell sorting also crosses realms of Chain.

His most cited work include:

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition) (345 citations)
  • Extensive immunoglobulin production sensitizes myeloma cells for proteasome inhibition. (320 citations)
  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (301 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Molecular biology, Cell biology, B cell, Antibody and Receptor. In his study, Somatic hypermutation is inextricably linked to Gene, which falls within the broad field of Molecular biology. Hans-Martin Jäck combines subjects such as Transcription factor, Immune system, Immunology, microRNA and B-cell receptor with his study of Cell biology.

Hans-Martin Jäck has included themes like breakpoint cluster region and Stromal cell in his B-cell receptor study. Hans-Martin Jäck works mostly in the field of B cell, limiting it down to topics relating to Naive B cell and, in certain cases, B-1 cell, as a part of the same area of interest. His research integrates issues of Antigen and Virology in his study of Antibody.

He most often published in these fields:

  • Molecular biology (43.38%)
  • Cell biology (32.35%)
  • B cell (24.26%)

What were the highlights of his more recent work (between 2017-2021)?

  • Antibody (20.59%)
  • Virology (10.29%)
  • Cell biology (32.35%)

In recent papers he was focusing on the following fields of study:

Hans-Martin Jäck mainly focuses on Antibody, Virology, Cell biology, Severe acute respiratory syndrome coronavirus 2 and Receptor. His Antibody research incorporates elements of Disease and Bone marrow. His Cell biology study incorporates themes from Plasma cell, Immune system and B cell.

His Plasma cell study integrates concerns from other disciplines, such as Humoral immunity and Transcriptome. His research in B cell is mostly concerned with B-cell receptor. His Receptor research includes themes of Plasma cell differentiation and Transcription factor.

Between 2017 and 2021, his most popular works were:

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition) (345 citations)
  • SARS-CoV-2 variants B.1.351 and P.1 escape from neutralizing antibodies. (42 citations)
  • SARS-CoV-2 variants B.1.351 and B.1.1.248: Escape from therapeutic antibodies and antibodies induced by infection and vaccination (33 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Enzyme

His primary areas of study are Antibody, Vaccination, Blockade, Virology and Recombinant DNA. Plasma cell and Autoimmune disease are subfields of Antibody in which his conducts study. His Cell culture research extends to the thematically linked field of Vaccination.

His biological study spans a wide range of topics, including Neutralization and Neutralizing antibody.

Best Publications

  • The Omicron variant is highly resistant against antibody-mediated neutralization: Implications for control of the COVID-19 pandemic

    Unknown

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies

    Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Mübeccel Akdis

  • SARS-CoV-2 variants B.1.351 and P.1 escape from neutralizing antibodies.

    Markus Hoffmann;Markus Hoffmann;Prerna Arora;Prerna Arora;Rüdiger Groß;Alina Seidel

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

    Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Andreas Acs

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)

    Unknown

  • Extensive immunoglobulin production sensitizes myeloma cells for proteasome inhibition.

    Silke Meister;Ulrich Schubert;Kirsten Neubert;Kai Herrmann

  • Serum microRNAs as powerful cancer biomarkers.

    Jürgen Wittmann;Hans-Martin Jäck

  • hUPF2 Silencing Identifies Physiologic Substrates of Mammalian Nonsense-Mediated mRNA Decay

    Jürgen Wittmann;Elly M. Hol;Hans-Martin Jäck

  • CD30 is a signal-transducing molecule that defines a subset of human activated CD45RO+ T cells.

    T M Ellis;P E Simms;D J Slivnick;H M Jäck

  • Omicron sublineage BQ.1.1 resistance to monoclonal antibodies

    Unknown

  • Circular DNA is a product of the immunoglobulin class switch rearrangement

    von Schwedler U;Jäck Hm;Wabl M

  • IgA plasma cells in vascular tissue of patients with Kawasaki syndrome.

    Anne H. Rowley;Carrie A. Eckerley;Hans Martin Jäck;Stanford T. Shulman

  • Inhibition of JAK3 and STAT6 Tyrosine Phosphorylation by the Immunosuppressive Drug Leflunomide Leads to a Block in IgG1 Production

    Karyn Siemasko;Anita S-F. Chong;Hans-Martin Jäck;Haihua Gong

  • Cloning and characterization of HUPF1, a human homolog of the Saccharomyces cerevisiae nonsense mRNA-reducing UPF1 protein.

    Steven E. Applequist;Manuel Selg;Chander Raman;Hans-Martin Jäck

  • SARS-CoV-2 variant B.1.617 is resistant to bamlanivimab and evades antibodies induced by infection and vaccination.

    Markus Hoffmann;Markus Hoffmann;Heike Hofmann-Winkler;Nadine Krüger;Amy Kempf;Amy Kempf

  • Comparable neutralisation evasion of SARS-CoV-2 omicron subvariants BA.1, BA.2, and BA.3

    Unknown

  • Stages of Germinal Center Transit Are Defined by B Cell Transcription Factor Coexpression and Relative Abundance

    Giorgio Cattoretti;Rita Shaknovich;Paula M. Smith;Hans-Martin Jäck

  • Expression of BLIMP1/PRMT5 and concurrent histone H2A/H4 arginine 3 dimethylation in fetal germ cells, CIS/IGCNU and germ cell tumors

    Dawid Eckert;Katharina Biermann;Daniel Nettersheim;Ad J M Gillis

  • Interaction of Murine Precursor B Cell Receptor with Stroma Cells Is Controlled by the Unique Tail of λ5 and Stroma Cell-Associated Heparan Sulfate

    Harald Bradl;Jürgen Wittmann;Doreen Milius;Christian Vettermann

  • Surrogate light chain-dependent selection of Ig heavy chain V regions.

    U Keyna;G B Beck-Engeser;J Jongstra;S E Applequist

  • CD30 defines a subset of activated human T cells that produce IFN-gamma and IL-5 and exhibit enhanced B cell helper activity.

    M Alzona;H M Jäck;R I Fisher;T M Ellis

  • BCL6 is critical for the development of a diverse primary B cell repertoire

    Cihangir Duy;J. Jessica Yu;Rahul Nahar;Srividya Swaminathan

  • Pre-B cell receptor-mediated cell cycle arrest in Philadelphia chromosome-positive acute lymphoblastic leukemia requires IKAROS function

    Daniel Trageser;Ilaria Iacobucci;Rahul Nahar;Cihangir Duy;Cihangir Duy

  • Induction of pre-B cell proliferation after de novo synthesis of the pre-B cell receptor.

    Jochen Hess;Annick Werner;Thomas Wirth;Fritz Melchers

Frequent Co-Authors

Matthias Wabl
Matthias Wabl University of California, San Francisco
Stefan Pöhlmann
Stefan Pöhlmann German Primate Center
Andreas Radbruch
Andreas Radbruch German Rheumatism Research Centre
Thomas H. Winkler
Thomas H. Winkler University of Erlangen-Nuremberg
Michael R. Bösl
Michael R. Bösl University of Würzburg
Michael Karas
Michael Karas Goethe University Frankfurt
Jenny Mjösberg
Jenny Mjösberg Karolinska Institute
Martin Herrmann
Martin Herrmann University of Erlangen-Nuremberg
Chander Raman
Chander Raman University of Alabama at Birmingham
Klaus Überla
Klaus Überla University of Erlangen-Nuremberg

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