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Genetics

D-Index
47
Citations
33026
World Ranking
4073
National Ranking
18

Overview

Denise Harold is affiliated with Dublin City University in Ireland and has contributed to the field of Biochemistry, Genetics and Molecular Biology with a total of 18 publications. Their research spans several specialized subfields including Genetics, Molecular Biology, Clinical Biochemistry, Immunology, and Pollution.

The main topics covered by Denise Harold's work include:

  • Mitochondrial Function and Pathology
  • Metabolism and Genetic Disorders
  • Genomics and Rare Diseases
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Genomic Variations and Chromosomal Abnormalities
  • Genetic Associations and Epidemiology
  • Tryptophan and Brain Disorders

Their recent papers reflect a focus on both environmental studies and clinical genetics. Notable publications include:

  • A review of pharmaceutical occurrence and pathways in the aquatic environment in the context of a changing climate and the COVID-19 pandemic, 2021, Analytical Methods
  • Monitoring of emerging contaminants of concern in the aquatic environment: a review of studies showing the application of effect-based measures, 2021, Analytical Methods
  • Rare Copy Number Variants Are Associated With Poorer Cognition in Schizophrenia, 2020, Biological Psychiatry
  • Mito-SiPE is a sequence-independent and PCR-free mtDNA enrichment method for accurate ultra-deep mitochondrial sequencing, 2022, Communications Biology
  • Identifying schizophrenia patients who carry pathogenic genetic copy number variants using standard clinical assessment: retrospective cohort study, 2020, The British Journal of Psychiatry

The scientist has frequently published in venues such as Analytical Methods and bioRxiv (Cold Spring Harbor Laboratory), as well as UNC Libraries, Biological Psychiatry, and Communications Biology.

Their work has been conducted in collaboration with several frequent co-authors, including Anne Parle-McDermott, Derek W. Morris, Aiden Corvin, David J. Bernard, and Faith Pangilinan.

Best Publications

  • Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

    Jean-Charles Lambert;Jean-Charles Lambert;Jean-Charles Lambert;Carla A Ibrahim-Verbaas;Denise Harold;Adam C Naj

  • Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

    Denise Harold;Richard Abraham;Paul Hollingworth;Rebecca Sims

  • Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease (Nature Genetics (2009) 41 (1088-1093))

    D Harold;R Abraham;P Hollingworth;R Sims

  • Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.

    Paul Hollingworth;Denise Harold;Rebecca Sims;Amy Gerrish

  • Analysis of shared heritability in common disorders of the brain

    Verneri Anttila;Verneri Anttila;Brendan Bulik-Sullivan;Brendan Bulik-Sullivan;Hilary K. Finucane;Raymond K. Walters;Raymond K. Walters

  • Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

    Antonio F. Pardiñas;Peter Holmans;Andrew J. Pocklington;Valentina Escott-Price

  • Genome-wide analysis of genetic loci associated with Alzheimer disease.

    Sudha Seshadri;Annette L. Fitzpatrick;M Arfan Ikram;Anita L. DeStefano

  • Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.

    Valentina Escott-Price;Céline Bellenguez;Li-San Wang;Seung-Hoan Choi

  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

    Rebecca Sims;Sven J. Van Der Lee;Adam C. Naj;Céline Bellenguez;Céline Bellenguez

  • Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease.

    Lesley Jones;Peter A. Holmans;Marian L. Hamshere;Denise Harold

  • Identification of Genetic Factors that Modify Clinical Onset of Huntington’s Disease

    Jong-Min Lee;Vanessa C. Wheeler;Michael J. Chao;Jean Paul G. Vonsattel

  • Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology.

    J Chapuis;F Hansmannel;M Gistelinck;A Mounier

  • Strong evidence that KIAA0319 on chromosome 6p is a susceptibility gene for developmental dyslexia

    Natalie Cope;Denise Harold;Gary Hill;Valentina Moskvina

  • Common polygenic variation enhances risk prediction for Alzheimer's disease.

    Valentina Escott-Price;Rebecca Sims;Christian Bannister;Denise Harold

  • GWAS of Cerebrospinal Fluid Tau Levels Identifies Risk Variants for Alzheimer’s Disease

    Carlos Cruchaga;John S.K. Kauwe;Oscar Harari;Sheng Chih Jin

  • A novel Alzheimer disease locus located near the gene encoding tau protein

    G. Jun;C. A. Ibrahim-Verbaas;M. Vronskaya;J-C Lambert;J-C Lambert;J-C Lambert

  • Remapping the insulin gene/IDDM2 locus in type 1 diabetes.

    Bryan J. Barratt;Felicity Payne;Chris E. Lowe;Robert Hermann

  • Estimation and partitioning of polygenic variation captured by common SNPs for Alzheimer's disease, multiple sclerosis and endometriosis

    S. Hong Lee;S. Hong Lee;Denise Harold;Dale R. Nyholt;Michael E. Goddard

  • Further evidence that the KIAA0319 gene confers susceptibility to developmental dyslexia.

    D Harold;S Paracchini;T Scerri;M Dennis;M Dennis

  • Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimertextquotesingles disease

    Denise Harold;Richard Abraham;Paul Hollingworth;Rebecca Sims

Frequent Co-Authors

Julie Williams
Julie Williams Cardiff University
Michael John Owen
Michael John Owen Cardiff University
Michael Conlon O'Donovan
Michael Conlon O'Donovan Cardiff University
Michael Gill
Michael Gill Trinity College Dublin
Simon Lovestone
Simon Lovestone University of Oxford
Peter Holmans
Peter Holmans Cardiff University
Alison Goate
Alison Goate Icahn School of Medicine at Mount Sinai
Céline Bellenguez
Céline Bellenguez Institut Pasteur
John Hardy
John Hardy University College London

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