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Chemistry

D-Index
63
Citations
11360
World Ranking
8617
National Ranking
2464

Overview

David S. Cafiso is affiliated with the University of Virginia in the United States. Their publication record focuses primarily on Biochemistry, Genetics and Molecular Biology, with a total of 36 publications. Within this broad field, they have contributed significantly to subfields such as Molecular Biology, Cell Biology, Biophysics, Plant Science, and Infectious Diseases.

The main research topics covered by Cafiso include cellular transport and secretion, lipid membrane structure and behavior, electron spin resonance studies, porphyrin metabolism and disorders, ion channel regulation and function, viral infections and outbreaks research, and interferon and immune responses. These areas highlight a multidisciplinary approach to understanding biological membranes and protein interactions.

Key recent papers published by Cafiso include:

  • Ebola virus glycoprotein interacts with cholesterol to enhance membrane fusion and cell entry, 2021, Nature Structural & Molecular Biology
  • Conserved arginine residues in synaptotagmin 1 regulate fusion pore expansion through membrane contact, 2021, Nature Communications
  • Structural intermediates observed only in intact Escherichia coli indicate a mechanism for TonB-dependent transport, 2021, eLife
  • Evidence for the Supramolecular Organization of a Bacterial Outer-Membrane Protein from In Vivo Pulse Electron Paramagnetic Resonance Spectroscopy, 2020, Journal of the American Chemical Society
  • Unlocking Biradical Character in Diborepins, 2024, Journal of the American Chemical Society

Repeated collaborations are noted with several coauthors including Lukas K. Tamm, Volker Kiessling, David A. Nyenhuis, Binyong Liang, and Thushani D. Nilaweera. These collaborations reflect ongoing research partnerships within molecular and biophysical studies.

Cafiso's publications are frequently found in venues such as Biophysical Journal, Journal of the American Chemical Society, bioRxiv (Cold Spring Harbor Laboratory), Nature Structural & Molecular Biology, and Nature Communications. The Biophysical Journal is the most frequent venue, hosting 12 of their publications.

Best Publications

  • Identifying conformational changes with site-directed spin labeling.

    Wayne L. Hubbell;David S. Cafiso;Christian Altenbach

  • Membrane structure and fusion-triggering conformational change of the fusion domain from influenza hemagglutinin.

    Xing Han;John H. Bushweller;David S. Cafiso;Lukas K. Tamm

  • Recent advances and applications of site-directed spin labeling

    Gail E Fanucci;David S Cafiso

  • Electrostatic sequestration of PIP2 on phospholipid membranes by basic/aromatic regions of proteins.

    Alok Gambhir;Gyöngyi Hangyás-Mihályné;Irina Zaitseva;David S. Cafiso

  • Alamethicin: A Peptide Model for Voltage Gating and Protein-Membrane Interactions

    D S Cafiso

  • Internal electrostatic potentials in bilayers: measuring and controlling dipole potentials in lipid vesicles

    J.C. Franklin;D.S. Cafiso

  • NMR Solution Structure of the Integral Membrane Enzyme DsbB: Functional Insights into DsbB-Catalyzed Disulfide Bond Formation

    Yunpeng Zhou;Tomasz Cierpicki;Ricardo H. Flores Jimenez;Stephen M. Lukasik

  • The Role of Proline and Glycine in Determining the Backbone Flexibility of a Channel-Forming Peptide

    Jaison Jacob;Herve Duclohier;David S. Cafiso

  • Membrane orientation and position of the C2 domain from cPLA2 by site-directed spin labeling.

    April A Frazier;Mark A Wisner;Nathan J Malmberg;Kenneth G Victor

  • Position of Synaptotagmin I at the Membrane Interface: Cooperative Interactions of Tandem C2 Domains†

    Dawn Z. Herrick;Stephenie Sterbling;Katie A. Rasch;and Anne Hinderliter

  • Dynamic structure of lipid-bound synaptobrevin suggests a nucleation-propagation mechanism for trans-SNARE complex formation

    Jeffrey F. Ellena;Binyong Liang;Maciej Wiktor;Alexander Stein

  • Synaptotagmin-1 binds to PIP2-containing membrane but not to SNAREs at physiological ionic strength.

    Yongsoo Park;Jong Bae Seo;Alicia Fraind;Angel Pérez-Lara

  • Membrane orientation of the N-terminal segment of alamethicin determined by solid-state 15N NMR.

    C.L. North;M. Barranger-Mathys;D.S. Cafiso

  • Membrane-bound orientation and position of the synaptotagmin I C2A domain by site-directed spin labeling.

    April A. Frazier;Christina R. Roller;Jessica J. Havelka;and Anne Hinderliter

  • Substrate-induced exposure of an energy-coupling motif of a membrane transporter.

    Helen J. Merianos;Nathalie Cadieux;Cindy H. Lin;Robert J. Kadner

  • Solution structure of the ESCRT-I complex by small-angle X-ray scattering, EPR, and FRET spectroscopy

    Evzen Boura;Bartosz Różycki;Dawn Z. Herrick;Hoi Sung Chung

  • Myristoylated alanine-rich C kinase substrate (MARCKS) sequesters spin-labeled phosphatidylinositol 4,5-bisphosphate in lipid bilayers

    Michelle E. Rauch;Colin G. Ferguson;Glenn D. Prestwich;David S. Cafiso

  • EPR Determination of Membrane Potentials

    David S. Cafiso;Wayne L. Hubbell

  • Additional component required for activity and reconstitution of light-activated vertebrate photoreceptor GTPase

    T Shinozawa;S Uchida;E Martin;D Cafiso

  • Electrostatics of phosphoinositide bilayer membranes. Theoretical and experimental results.

    M. Langner;D. Cafiso;S. Marcelja;S. McLaughlin

Frequent Co-Authors

Wayne L. Hubbell
Wayne L. Hubbell University of California, Los Angeles
Reinhard Jahn
Reinhard Jahn Max Planck Society
John H. Bushweller
John H. Bushweller University of Virginia
Robert J. Kadner
Robert J. Kadner University of Virginia
Thomas F. Prisner
Thomas F. Prisner Goethe University Frankfurt
Judith M. White
Judith M. White University of Virginia
Stuart McLaughlin
Stuart McLaughlin Stony Brook University
Kai Tittmann
Kai Tittmann University of Göttingen
Jon Beckwith
Jon Beckwith Harvard University
Nir Ben-Tal
Nir Ben-Tal Tel Aviv University

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