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David J. Robbins

David J. Robbins

D-Index & Metrics

Biology and Biochemistry

D-Index
60
Citations
16724
World Ranking
11773
National Ranking
5063

Overview

David J. Robbins is affiliated with Dartmouth College in the United States and works primarily in the field of Biochemistry, Genetics and Molecular Biology. Their research output comprises 64 publications in this area, with significant contributions to molecular biology and genetics.

The scientist's subfields of study include:

  • Molecular Biology
  • Genetics
  • Immunology
  • Ocean Engineering
  • Health, Toxicology and Mutagenesis

David J. Robbins has focused on topics such as:

  • Wnt/β-catenin signaling in development and cancer
  • Cancer-related gene regulation
  • Epigenetics and DNA Methylation
  • Hedgehog Signaling Pathway Studies
  • Protein purification and stability
  • Chromatin Remodeling and Cancer
  • Protein Degradation and Inhibitors

Their recent papers include:

  • "Nuclear Regulation of Wnt/β-Catenin Signaling: It's a Complex Situation," 2020, Genes
  • "Opioids Impair Intestinal Epithelial Repair in HIV-Infected Humanized Mice," 2020, Frontiers in Immunology
  • "The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling," 2021, Nature Communications
  • "Pharmacological Disruption of the Notch1 Transcriptional Complex Inhibits Tumor Growth by Selectively Targeting Cancer Stem Cells," 2021, Cancer Research
  • "Casein Kinase 1α as a Regulator of Wnt-Driven Cancer," 2020, International Journal of Molecular Sciences

Frequent co-authors collaborating with David J. Robbins are:

  • Daniel T. Wynn
  • Yashi Ahmed
  • Ethan Lee
  • Nagi G. Ayad
  • Chen Shen

The scholar has published multiple works in key venues, including:

  • Nature Communications
  • Neuro-Oncology
  • Cancer Research
  • Journal of Chromatography A
  • Genes

Best Publications

  • ERKs: A family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF

    Teri G. Boulton;Steven H. Nye;David J. Robbins;Nancy Y. Ip

  • Atomic structure of the MAP kinase ERK2 at 2.3 A resolution.

    Faming Zhang;Arne Strand;David Robbins;Melanie H. Cobb

  • The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the map kinase pathway and induces cell proliferation.

    Estelle Sontag;Sergei Fedorov;Craig Kamibayashi;David Robbins

  • Extracellular signal-regulated kinases: ERKs in progress

    Melanie H. Cobb;Teri G. Boulton;David J. Robbins

  • Regulation and properties of extracellular signal-regulated protein kinases 1 and 2 in vitro

    David J. Robbins;Erzhen Zhen;Hajime Owaki;Colleen A. Vanderbilt

  • A freely diffusible form of Sonic hedgehog mediates long-range signalling

    Xin Zeng;John A. Goetz;Liza M. Suber;William J. Scott

  • Hedgehog elicits signal transduction by means of a large complex containing the kinesin-related protein costal2.

    David J Robbins;Kent E Nybakken;Ryuji Kobayashi;John C Sisson

  • The Hedgehog Signal Transduction Network

    David J. Robbins;Dennis Liang Fei;Natalia A. Riobo

  • Evidence for a Ras-dependent extracellular signal-regulated protein kinase (ERK) cascade.

    David J. Robbins;Mangeng Cheng;Erzhen Zhen;Colleen A. Vanderbilt

  • G protein Gαi functions immediately downstream of Smoothened in Hedgehog signalling

    Stacey K. Ogden;Dennis Liang Fei;Neal S. Schilling;Yashi F. Ahmed

  • Shk1, a homolog of the Saccharomyces cerevisiae Ste20 and mammalian p65PAK protein kinases, is a component of a Ras/Cdc42 signaling module in the fission yeast Schizosaccharomyces pombe

    Stevan Marcus;Anthony Polverino;Anthony Polverino;Eric Chang;David Robbins

  • MEKK1 phosphorylates MEK1 and MEK2 but does not cause activation of mitogen-activated protein kinase.

    Shuichan Xu;David Robbins;David Robbins;Jeffrey A Frost;Alphonsus Dang

  • TGFβ2 mediates the effects of Hedgehog on hypertrophic differentiation and PTHrP expression

    Jesus Alvarez;Philip Sohn;Xin Zeng;Thomas Doetschman

  • Frequent requirement of hedgehog signaling in non-small cell lung carcinoma

    Z Yuan;J A Goetz;S Singh;S K Ogden

  • The mitogen-activated protein kinases, ERK1 and ERK2

    Melanie H. Cobb;Jessie E. Hepler;Mangeng Cheng;David Robbins

  • Characterization of a High-Molecular-Weight Notch Complex in the Nucleus of Notchic-Transformed RKE Cells and in a Human T-Cell Leukemia Cell Line

    Shawn Jeffries;David J. Robbins;Anthony J. Capobianco

  • Cloning of rat MEK kinase 1 cDNA reveals an endogenous membrane-associated 195-kDa protein with a large regulatory domain.

    Shuichan Xu;David J. Robbins;David J. Robbins;Lori B. Christerson;Jessie M. English

  • ERKs, extracellular signal-regulated MAP-2 kinases.

    Melanie H. Cobb;David J. Robbins;Teri G. Boulton

  • A Highly Conserved Amino-terminal Region of Sonic Hedgehog Is Required for the Formation of Its Freely Diffusible Multimeric Form

    John A. Goetz;Samer Singh;Liza M. Suber;F. Jon Kull

  • Identification of a functional interaction between the transmembrane protein Smoothened and the kinesin-related protein Costal2.

    Stacey K. Ogden;Manuel Ascano;Manuel Ascano;Melanie A. Stegman;Melanie A. Stegman;Liza M. Suber

Frequent Co-Authors

Melanie H. Cobb
Melanie H. Cobb The University of Texas Southwestern Medical Center
Carmen J. Marsit
Carmen J. Marsit Emory University
Margaret R. Karagas
Margaret R. Karagas Dartmouth College
Corey Cutler
Corey Cutler Harvard University
Elizabeth J. Goldsmith
Elizabeth J. Goldsmith The University of Texas Southwestern Medical Center
Michael Wigler
Michael Wigler Cold Spring Harbor Laboratory
J. Michael Bishop
J. Michael Bishop University of California, San Francisco
Cyril H. Benes
Cyril H. Benes Harvard University
Thomas H. Lee
Thomas H. Lee Harvard University
John W. Haycock
John W. Haycock Louisiana State University Health Sciences Center New Orleans

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