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Biology and Biochemistry

D-Index
40
Citations
8382
World Ranking
19580
National Ranking
7978

Overview

David C. Pallas is a researcher affiliated with Emory University in the United States with expertise primarily in the field of Medicine. Their work spans several specialized subfields, including Oncology, Hepatology, Surgery, Pulmonary and Respiratory Medicine, and Epidemiology.

Their recent scholarly contributions include publications in multiple peer-reviewed journals. Notable papers authored or co-authored by them are:

  • Heterogeneity in adverse events related to atezolizumab-bevacizumab for hepatocellular carcinoma reported in real-world studies, 2024, published in JHEP Reports
  • Left Atrial Compression by an Intramural Hematoma: A Rare Case of Obstructive Shock, 2024, published in Cureus
  • Molecular Diagnosis and Identification of a Novel Pathogenic Variant in Autosomal Dominant Polycystic Kidney Disease (ADPKD): A Case in Full Bloom, 2025, published in Cureus

The researcher collaborates frequently with other scientists including Claudia Campani, Sabrina Sidali, Όλγα Γιουλεμέ, Lorraine Blaise, and Véronique Grando. Their collective work encompasses topics related to cancer research as well as cardiovascular and renal conditions.

Common venues for their publications include the journals Cureus and JHEP Reports, reflecting a focus on clinical and translational medicine.

David C. Pallas's research interests cover a range of main topics such as:

  • Hepatocellular Carcinoma Treatment and Prognosis
  • Colorectal Cancer Treatments and Studies
  • Cancer Immunotherapy and Biomarkers
  • Cardiac Structural Anomalies and Repair
  • Aortic Disease and Treatment Approaches
  • Infective Endocarditis Diagnosis and Management

The scientific output leans toward investigation and analysis of complex disease processes including both oncologic and cardiovascular conditions. Their multidisciplinary approach integrates clinical case studies with molecular diagnostic techniques.

Best Publications

  • Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A.

    David C. Pallas;Lilian K. Shahrik;Bruce L. Martin;Stephen Jaspers

  • Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity

    David R. Kaplan;Malcolm Whitman;Brian Schaffhausen;David C. Pallas

  • Identification of cellular proteins that can interact specifically with the T/ElA-binding region of the retinoblastoma gene product

    William G. Kaelin;David C. Pallas;James A. DeCaprio;Frederic J. Kaye

  • Identification of specific PP2A complexes involved in human cell transformation

    Wen Chen;Richard Possemato;Richard Possemato;K.Thirza Campbell;Courtney A Plattner

  • Striatin assembles a membrane signaling complex necessary for rapid, nongenomic activation of endothelial NO synthase by estrogen receptor α

    Qing Lu;David C. Pallas;Howard K. Surks;Wendy E. Baur

  • Interaction of the protein kinase Raf-1 with 14-3-3 proteins

    Haian Fu;Kai Xia;D. C. Pallas;Can Cui

  • Analysis of the Adenovirus E1B-55K-Anchored Proteome Reveals Its Link to Ubiquitination Machinery

    Josephine N. Harada;Anna Shevchenko;Andrej Shevchenko;David C. Pallas

  • FMRP Phosphorylation Reveals an Immediate-Early Signaling Pathway Triggered by Group I mGluR and Mediated by PP2A

    Usha Narayanan;Vijayalaxmi Nalavadi;Mika Nakamoto;David C. Pallas

  • Phosphatidylinositol metabolism and polyoma-mediated transformation.

    David R. Kaplan;Malcolm Whitman;Brian Schaffhausen;Leda Raptis

  • A Protein Phosphatase Methylesterase (PME-1) Is One of Several Novel Proteins Stably Associating with Two Inactive Mutants of Protein Phosphatase 2A

    Egon Ogris;Egon Ogris;Xianxing Du;Kasey C. Nelson;Kasey C. Nelson;Elsa K. Mak

  • STRIPAK complexes: structure, biological function, and involvement in human diseases.

    Juyeon Hwang;David C. Pallas

  • WD40 Repeat Proteins Striatin and S/G2 Nuclear Autoantigen Are Members of a Novel Family of Calmodulin-binding Proteins That Associate with Protein Phosphatase 2A

    Carlos S. Moreno;Susan Park;Kasey Nelson;Danita Ashby

  • Polyoma middle tumor antigen interacts with SHC protein via the NPTY (Asn-Pro-Thr-Tyr) motif in middle tumor antigen

    Kathryn S. Campbell;Egon Ogris;Brenda Burke;Wen Su

  • Association of polyomavirus middle tumor antigen with 14-3-3 proteins

    D. C. Pallas;Haian Fu;L. C. Haehnel;W. Weller

  • Methylation of the Protein Phosphatase 2A Catalytic Subunit Is Essential for Association of Bα Regulatory Subunit But Not SG2NA, Striatin, or Polyomavirus Middle Tumor Antigen

    Xing Xian Yu;Xianxing Du;Carlos S. Moreno;Richard E. Green

  • Protein phosphatase 2A subunit assembly: the catalytic subunit carboxy terminus is important for binding cellular B subunit but not polyomavirus middle tumor antigen

    Egon Ogris;Daryl M Gibson;David C Pallas;David C Pallas

  • Carboxymethylation of the PP2A catalytic subunit in Saccharomyces cerevisiae is required for efficient interaction with the B-type subunits Cdc55p and Rts1p.

    Huijun Wei;Danita G. Ashby;Carlos S. Moreno;Egon Ogris

  • A mammalian homolog of yeast MOB1 is both a member and a putative substrate of striatin family-protein phosphatase 2A complexes.

    Carlos S. Moreno;William S. Lane;David C. Pallas

  • Polyomavirus small t antigen: overproduction in bacteria, purification, and utilization for monoclonal and polyclonal antibody production.

    D C Pallas;C Schley;M Mahoney;E Harlow

  • Protein phosphatase 2a (PP2A) binds within the oligomerization domain of striatin and regulates the phosphorylation and activation of the mammalian Ste20-Like kinase Mst3

    Johnthan Gordon;Juyeon Hwang;Karma J Carrier;Candace A Jones

Frequent Co-Authors

Thomas M. Roberts
Thomas M. Roberts Harvard University
Brian Schaffhausen
Brian Schaffhausen Tufts University
Carlos S. Moreno
Carlos S. Moreno Emory University
David L. Kaplan
David L. Kaplan Tufts University
William S. Lane
William S. Lane Harvard University
William C. Hahn
William C. Hahn Dana-Farber Cancer Institute
Richard H. Karas
Richard H. Karas Tufts University
Anthony J. Koleske
Anthony J. Koleske Yale University
Alfred H. Merrill
Alfred H. Merrill Georgia Institute of Technology
Robert J Collier
Robert J Collier University of Arizona

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